Results 31 to 40 of about 577,400 (301)
Global Evolution of Pathogenic Bacteria With Extensive Use of Fluoroquinolone Agents
Frontiers in Microbiology, 2020 It is well-established that the spread of many multidrug-resistant (MDR) bacteria is predominantly clonal. Interestingly the international clones/sequence types (STs) of most pathogens emerged and disseminated during the last three decades.
Miklos Fuzi +2 more
doaj +1 more source
Journal of Fungi, 2021 Powdery mildew is caused by Podosphaera xanthii, and is one of the most important diseases that attacks Spanish cucurbit crops. Fungicide application is the primary control tool; however, its effectiveness is hampered by the rapid development of ...
Alejandra Vielba-Fernández +5 more
doaj +1 more source
Quorum sensing regulates heteroresistance in Pseudomonas aeruginosa
Frontiers in Microbiology, 2022 The prevalence and genetic mechanism of antibiotic heteroresistance (HR) have attracted significant research attention recently. However, non-genetic mechanism of HR has not been adequately explored. The present study aimed to evaluate the role of quorum
Yang Lu +12 more
doaj +1 more source
The relative fitness of drug-resistant Mycobacterium tuberculosis: a modelling study of household transmission in Peru. [PDF]
, 2017 The relative fitness of drug-resistant versus susceptible bacteria in an environment dictates resistance prevalence. Estimates for the relative fitness of resistant Mycobacterium tuberculosis (Mtb) strains are highly heterogeneous and mostly derived from
Friedland, JS +5 more
core +7 more sources
Optimal phenotypic plasticity in a stochastic environment minimizes the cost/benefit ratio [PDF]
, 2012 This paper addresses the question of optimal phenotypic plasticity as a response to environmental fluctuations while optimizing the cost/benefit ratio, where the cost is energetic expense of plasticity, and benefit is fitness.
Coquillard, Patrick +2 more
core +5 more sources
Emergence of a High-Risk Klebsiella michiganensis Clone Disseminating Carbapenemase Genes
Frontiers in Microbiology, 2022 Klebsiella michiganensis is emerging as an important human pathogen of concern especially strains with plasmid-mediated carbapenemase genes. The IncX3-blaNDM-5 plasmid has been described as the primary vector for blaNDM-5 dissemination.
Isaac Prah +6 more
doaj +1 more source
The fitness costs of antibiotic resistance mutations [PDF]
Evolutionary Applications, 2014 AbstractAntibiotic resistance is increasing in pathogenic microbial populations and is thus a major threat to public health. The fate of a resistance mutation in pathogen populations is determined in part by its fitness. Mutations that suffer little or no fitness cost are more likely to persist in the absence of antibiotic treatment. In this review, we
Melnyk, Anita H +2 more
openaire +2 more sources
Mycobacterium tuberculosis: mechanisms and interactions between drug resistance mutations with fitness costs and the drug resistance phenotypes [PDF]
Infectious Diseases and Tropical Medicine, 2022 Multidrug-resistant and extensively drug-resistant Mycobacterium tuberculosis are no news and have contributed to the continued scourge of tuberculosis today. Acquisition of drug resistance by M.
R. Olamilekan Adesola +1 more
doaj +1 more source
Cost-Based Fitness in Conformance Checking
2011 Eleventh International Conference on Application of Concurrency to System Design, 2011 Experience in business process analysis shows that operational processes often do not conform to process models. Although classical conformance checking techniques can identify deviations of process executions from predefined models, they may produce inaccurate results due to strong assumptions.
Adriansyah, A. +2 more
openaire +2 more sources
Fitness Cost of Chromosomal Drug Resistance-Conferring Mutations [PDF]
Antimicrobial Agents and Chemotherapy, 2002 ABSTRACTTo study the cost of chromosomal drug resistance mutations to bacteria, we investigated the fitness cost of mutations that confer resistance to different classes of antibiotics affecting bacterial protein synthesis (aminocyclitols, 2-deoxystreptamines, macrolides).
Sander, Peter +6 more
openaire +2 more sources