Results 31 to 40 of about 126,813 (257)

One problem, too many solutions: How costly is honest signalling of need?

open access: yesPLoS ONE, 2019
The "cost of begging" is a prominent prediction of costly signalling theory, suggesting that offspring begging has to be costly in order to be honest. Seminal signalling models predict that there is a unique equilibrium cost function for the offspring ...
Szabolcs Számadó   +2 more
doaj   +1 more source

Fitness costs of resistance to antimalarial drugs

open access: yesTrends in Parasitology, 2008
It has been recently reported that the prevalence of mutations associated with chloroquine resistance declined during the dry season. Fitness costs of drug resistance were suggested to be responsible for reduced survival of mutant parasites, and only parasites surviving chronic infections were transmitted at the onset of the rainy season.
Felger Ingrid, Beck Hans-Peter
openaire   +4 more sources

Fitness cost of a mcr-1-carrying IncHI2 plasmid.

open access: yesPLoS ONE, 2018
IncHI2 is a common type of large mcr-1-carrying plasmids that have been found worldwide. Large plasmids could impose metabolic burden for host bacterial strains, we therefore examine the stability and fitness cost of a mcr-1-carrying 265.5-kb IncHI2 ...
Ke Ma, Yu Feng, Zhiyong Zong
doaj   +1 more source

Fitness costs of CRISPR-Cas systems in bacteria

open access: yesMicrobiology, 2022
CRISPR-Cas systems provide bacteria with both specificity and adaptability in defence against invading genetic elements. From a theoretical perspective, CRISPR-Cas systems confer many benefits. However, they are observed at an unexpectedly low prevalence across the bacterial domain.
Michael Zaayman, Rachel M. Wheatley
openaire   +2 more sources

Reducing the cost of evaluating the committor by a fitting procedure [PDF]

open access: yesThe Journal of Chemical Physics, 2015
Correct identification of reaction coordinates in complex systems is essential for understanding the mechanisms of their reaction dynamics. Existing methods for identifying reaction coordinates typically require knowledge of the committor—the probability of a given configuration to reach the product basin.
Wenjin Li, Ao Ma
openaire   +2 more sources

Fitness of Herbicide-Resistant Weeds: Current Knowledge and Implications for Management

open access: yesPlants, 2019
Herbicide resistance is the ultimate evidence of the extraordinary capacity of weeds to evolve under stressful conditions. Despite the extraordinary plant fitness advantage endowed by herbicide resistance mutations in agroecosystems under herbicide ...
Martin M. Vila-Aiub
doaj   +1 more source

Fitness Cost of Daptomycin-Resistant Staphylococcus aureus Obtained from in Vitro Daptomycin Selection Pressure

open access: yesFrontiers in Microbiology, 2017
Daptomycin-resistant (DAP-R) Staphylococcus aureus strains are well documented, but have not been reported in China. To elucidate the evolution adaptability and fitness cost of DAP-R S. aureus, three DAP susceptible strains, Pre3 (MRSA, ST239-t037), Pre5
Shuguang Li   +5 more
doaj   +1 more source

Metabolic Perturbations Caused by the Over-Expression of mcr-1 in Escherichia coli

open access: yesFrontiers in Microbiology, 2020
Rapid dissemination of the plasmid-born polymyxin resistance gene mcr-1 poses a critical medical challenge. MCR-1 expression is tightly controlled and imposes a fitness cost on the bacteria.
Yi-Yun Liu   +15 more
doaj   +1 more source

Interplay between strain fitness and transmission frequency determines prevalence of antimicrobial resistance

open access: yesFrontiers in Ecology and Evolution, 2023
The steep rise of infections caused by bacteria that are resistant to antimicrobial agents threatens global health. However, the association between antimicrobial use and the prevalence of resistance is not straightforward.
Amalia Bogri   +3 more
doaj   +1 more source

Characterization of a mcr-1 and CRISPR-Cas System Co-harboring Plasmid in a Carbapenemase-Producing High-Risk ST11 Klebsiella pneumoniae Strain

open access: yesFrontiers in Microbiology, 2021
We set out to study the prevalence of the mcr-1 gene in carbapenemase-producing Klebsiella pneumoniae (CPKP) strains, and to determine whether its presence is associated with a fitness cost.
Yi-Hsiang Cheng   +10 more
doaj   +1 more source

Home - About - Disclaimer - Privacy