Results 31 to 40 of about 126,813 (257)
One problem, too many solutions: How costly is honest signalling of need?
The "cost of begging" is a prominent prediction of costly signalling theory, suggesting that offspring begging has to be costly in order to be honest. Seminal signalling models predict that there is a unique equilibrium cost function for the offspring ...
Szabolcs Számadó +2 more
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Fitness costs of resistance to antimalarial drugs
It has been recently reported that the prevalence of mutations associated with chloroquine resistance declined during the dry season. Fitness costs of drug resistance were suggested to be responsible for reduced survival of mutant parasites, and only parasites surviving chronic infections were transmitted at the onset of the rainy season.
Felger Ingrid, Beck Hans-Peter
openaire +4 more sources
Fitness cost of a mcr-1-carrying IncHI2 plasmid.
IncHI2 is a common type of large mcr-1-carrying plasmids that have been found worldwide. Large plasmids could impose metabolic burden for host bacterial strains, we therefore examine the stability and fitness cost of a mcr-1-carrying 265.5-kb IncHI2 ...
Ke Ma, Yu Feng, Zhiyong Zong
doaj +1 more source
Fitness costs of CRISPR-Cas systems in bacteria
CRISPR-Cas systems provide bacteria with both specificity and adaptability in defence against invading genetic elements. From a theoretical perspective, CRISPR-Cas systems confer many benefits. However, they are observed at an unexpectedly low prevalence across the bacterial domain.
Michael Zaayman, Rachel M. Wheatley
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Reducing the cost of evaluating the committor by a fitting procedure [PDF]
Correct identification of reaction coordinates in complex systems is essential for understanding the mechanisms of their reaction dynamics. Existing methods for identifying reaction coordinates typically require knowledge of the committor—the probability of a given configuration to reach the product basin.
Wenjin Li, Ao Ma
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Fitness of Herbicide-Resistant Weeds: Current Knowledge and Implications for Management
Herbicide resistance is the ultimate evidence of the extraordinary capacity of weeds to evolve under stressful conditions. Despite the extraordinary plant fitness advantage endowed by herbicide resistance mutations in agroecosystems under herbicide ...
Martin M. Vila-Aiub
doaj +1 more source
Daptomycin-resistant (DAP-R) Staphylococcus aureus strains are well documented, but have not been reported in China. To elucidate the evolution adaptability and fitness cost of DAP-R S. aureus, three DAP susceptible strains, Pre3 (MRSA, ST239-t037), Pre5
Shuguang Li +5 more
doaj +1 more source
Metabolic Perturbations Caused by the Over-Expression of mcr-1 in Escherichia coli
Rapid dissemination of the plasmid-born polymyxin resistance gene mcr-1 poses a critical medical challenge. MCR-1 expression is tightly controlled and imposes a fitness cost on the bacteria.
Yi-Yun Liu +15 more
doaj +1 more source
The steep rise of infections caused by bacteria that are resistant to antimicrobial agents threatens global health. However, the association between antimicrobial use and the prevalence of resistance is not straightforward.
Amalia Bogri +3 more
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We set out to study the prevalence of the mcr-1 gene in carbapenemase-producing Klebsiella pneumoniae (CPKP) strains, and to determine whether its presence is associated with a fitness cost.
Yi-Hsiang Cheng +10 more
doaj +1 more source

