Results 41 to 50 of about 577,400 (301)
One problem, too many solutions: How costly is honest signalling of need?
PLoS ONE, 2019 The "cost of begging" is a prominent prediction of costly signalling theory, suggesting that offspring begging has to be costly in order to be honest. Seminal signalling models predict that there is a unique equilibrium cost function for the offspring ...
Szabolcs Számadó +2 more
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Frontiers in Cellular and Infection Microbiology, 2022 Hypervirulent variants of Klebsiella pnuemoniae (hvKP), which causes life-threatening infections, is a global priority pathogen and frequently harbours virulence plasmids. The virulence plasmids have emerged as the predominant vehicles carrying the major
Lin-Ping Fan +13 more
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Engineering Reports, 2020 Bacterial regulatory small RNAs (sRNAs) have shown promise for gene knock‐down studies and metabolic engineering. However, some mRNAs might be difficult to target due to poor binding by the Hfq chaperone, individual synthetic sRNAs can have off‐target ...
Carolin Vogel +5 more
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Fitness cost of a mcr-1-carrying IncHI2 plasmid.
PLoS ONE, 2018 IncHI2 is a common type of large mcr-1-carrying plasmids that have been found worldwide. Large plasmids could impose metabolic burden for host bacterial strains, we therefore examine the stability and fitness cost of a mcr-1-carrying 265.5-kb IncHI2 ...
Ke Ma, Yu Feng, Zhiyong Zong
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Modelling and in vitro testing of the HIV-1 Nef fitness landscape. [PDF]
, 2019 An effective vaccine is urgently required to curb the HIV-1 epidemic. We have previously described an approach to model the fitness landscape of several HIV-1 proteins, and have validated the results against experimental and clinical data.
Barton, John P +9 more
core +2 more sources
mSphere, 2019 In the present study, we provide the results of a detailed genomic analysis and the growth characteristics of a colistin-resistant KPC-3-producing Klebsiella pneumoniae sequence type 512 (ST512) isolate (the colR-KPC3-KP isolate) with a mutated pmrB and ...
Cesira Giordano +7 more
doaj +1 more source
Pathogens, 2022 We describe drug-resistance mutation dynamics of the gag gene among individuals under antiretroviral virologic failure who underwent analytical treatment interruption (ATI).
James R. Hunter +7 more
doaj +1 more source
Antibiotics, 2021 The emergence and prevalence of the tet(X) gene and its variants in the environment and in clinical settings constitute a growing concern for public health worldwide.
Lijie Jiang +4 more
doaj +1 more source
Fitness Cost of Resistance: Impact on Management [PDF]
, 2015 Fungicides are important tools for the management of fungal diseases in many crops. But eventually, most fungicides fail because the treated pathogen population evolves resistance to the fungicide. This chapter focuses on how our knowledge of fitness costs associated with resistance informs strategies of fungicide deployment that help to avoid or delay
Alexey Mikaberidze, Bruce A. McDonald
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Fitness costs of resistance to insecticides in insects
Frontiers in Physiology, 2023 The chemical application is considered one of the most crucial methods for controlling insect pests, especially in intensive farming practices. Owing to the chemical application, insect pests are exposed to toxic chemical insecticides along with other stress factors in the environment. Insects require energy and resources for survival and adaptation to
Gul, Hina +6 more
openaire +4 more sources