Results 91 to 100 of about 13,276,511 (306)

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Fixed-Time Synchronization Control for a Class of Master-Slave Systems Based on Homogeneous Method

, 2019
This brief investigates the fixed-time synchronization problem for a class of master-slave systems with second-order nonlinear dynamics via output feedback.
Guanghui Wen (18044428), Haibo Du (623698), Jinhu Lü (623401), Di Wu (23906)   +3 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Fixed sherwood duel optimization for time series imputation

IJAIN (International Journal of Advances in Intelligent Informatics)
Missing values remain a persistent challenge in time-series data, particularly within large-scale monitoring systems where reliable forecasting and evaluation are essential.
Agung Bella Putra Utama, Aji Prasetya Wibawa, Anik Nur Handayani, Andrew Nafalski   +3 more
doaj   +1 more source

The effects of delay-to-reinforcement, response requirement and schedule duration on performance under fixed-ratio schedules

, 2011
Experiment 1 examined the effects of delay-to-reinforcement on between-ratio pausing in multiple fixed-ratio 5 fixed-ratio 5 schedules. In one component the reinforcer was delivered immediately on completion of the ratio, and in the other there was a ...
Harris, Aimee Rebecca
core  

Fixed-time regulation of spacecraft orbit and attitude coordination with optimal actuation allocation using dual quaternion

, 2023
On-orbit service spacecraft with redundant actuators need to overcome orbital and attitude coupling when performing proximity maneuvers. In addition, transient/steady-state performance is required to fulfill the user-defined requirements.
B Xiao (9892946), A Montazeri (13667722), H Fei (13626250), L Sun (7715189), EM Yeatman (11539636), Z Wang (81545), Yanpei Huang (17385742)   +6 more
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

FEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga, Toshiki Takahashi, Akiko Kuma, Hiroyuki Kawahara   +3 more
wiley   +1 more source

Robust Fixed-Time 3D Trajectory Tracking Control for Underactuated AUVs Based on a Fixed-Time SSNN Disturbance Observer

IEEE Access
To address the problem of accurate tracking control for underactuated autonomous underwater vehicles (AUVs), a robust fixed-time control strategy is proposed to make AUVs converge to the desired reference trajectory in a fixed time.
Haitao Liu, Zhijian Feng, Xuehong Tian, Qingqun Mai   +3 more
doaj   +1 more source

Time-fixed geometry of 2nd order ordinary differential equations

, 2019
‎Let $y''=f(x,y,y')$ be a 2nd order ODE‎. ‎By Cartan equivalence‎ ‎method‎, ‎we will study the local equivalence problem under the‎ ‎transformations group of time-fixed coordinates‎. ‎We are going to‎ ‎solve this problem by an applicable method which has
Mehdi Nadjafikhah (6812084), Ahmad-Reza Forough (6814479)   +1 more
core   +1 more source