Results 121 to 130 of about 23,499 (227)

Expression, purification, and molecular characterization of plasmodium falciparum FK506-binding protein 35 (PfFKBP35)

, 2007
The immunosuppressive drug FK506 binds its targets FK506-binding protein (FKBP) family and modulates cellular processes. Recent studies demonstrated that FK506 shows anti-malaria effects.
Kang, Cong Bao, Yoon, Ho Sup, Chia, Joel, Tang, Kai, Yoon, Hye Rim   +4 more
core   +1 more source

The immunosuppressant FK506 inhibits amino acid import in Saccharomyces cerevisiae

, 1993
The immunosuppressants cyclosporin A, FK506, and rapamycin inhibit growth of unicellular eukaryotic microorganisms and also block activation of T lymphocytes from multicellular eukaryotes. In vitro, these compounds bind and inhibit two different types of
Hall, M. N., Movva, N. R., Koller, A., Schmidt, A., Kunz, J., Henriquez, R., Heitman, J.   +6 more
core  

Characterization of FK506 Biosynthetic Intermediates Involved in Post-PKS Elaboration

, 2016
The post-PKS modification steps of FK506 biosynthesis include C9-oxidation and 31-O-methylation, but the sequence of these reactions and the exact route have remained unclear.
Si-Kyu Lim (1346865), Myoung-Chong Song (1941856), Yeon Hee Ban (1941847), Pramod B. Shinde (1941844), Yeo Joon Yoon (1931188), Jae-yeon Hwang (1941850), Dong Hwan Kim (586776), Jae Kyung Sohng (1941853)   +7 more
core   +1 more source

FK506 and protein kinase C [PDF]

Nature, 1991
M, Tropschug, R, Hofmann
openaire   +2 more sources

Tacrolimus (FK506) Cerebral Blindness Following Translplantation

, 1995
Tacrolimus (FK506) is an immunosuppressant agent in use since 1984 to prevent graft rejection following transplantation. It is presumed similar to cyclosporine in its mode of action and its toxicity.
Todd C. Geis, MD; Nancy J. Newman, MD
core  

Combination of hydrotropic nicotinamide with nanoparticles for enhancing tacrolimus percutaneous delivery

International Journal of Nanomedicine, 2016
Wenhui Pan, Mengyao Qin, Guoguang Zhang, Yueming Long, Wenyi Ruan, Jingtong Pan, Zushuai Wu, Tao Wan, Chuanbin Wu, Yuehong Xu Department of Pharmaceutics, School of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou, People’s Republic of ...
Pan W, Qin M, Zhang G, Long Y, Ruan W, Pan J, Wu Z, Wan T, Wu C, Xu Y   +9 more
doaj  

Aneuploidy promotes transient stress adaptation and metabolic flexibility in the human fungal pathogen Aspergillus fumigatus. [PDF]

Curr Biol
Lehmann AE, Aguilar Ramírez E, Keller NP, Heitman J.   +3 more
europepmc   +1 more source

Enhanced ocular delivery of tacrolimus via cationic nanoliposomes: Mitigating inflammation and rebalancing Th17/Treg responses in dry eye disease. [PDF]

Mater Today Bio
Liu L, Chen D, Sheng S, Lin X, Zhao H, Liu C, Chen X, Ye Y, Xu W.   +8 more
europepmc   +1 more source

FK506: the promise and the paradox

Clinical and Experimental Immunology, 1991
openaire   +3 more sources

PEG-fusion of viable sciatic nerve isografts restores axonal structure and behavioral recovery after segmental-loss sciatic nerve injuries in Lewis rats. [PDF]

PLoS One
Yang CZ, Zhou L, Schafer AM, Olivarez AN, Periyasamy G, Gokhale V, Sood R, Garcia HA, Agarwal A, Alderete JF, Bittner GD.   +10 more
europepmc   +1 more source