Results 71 to 80 of about 36,346 (215)
Cell Transplantation, 2011 Previous rodent studies employing monotherapy or combined immunosuppressive regimens have demonstrated a variable degree of spinal xenograft survival in several spinal neurodegenerative models including spinal ischemia, trauma, or amyotrophic lateral ...
Michael P. Hefferan Ph.D. +5 more
doaj +1 more source
Heart failure in two male patients with late‐onset Fabry mutation (IVS4 + 919G > A)
ESC Heart Failure, Volume 12, Issue 2, Page 1508-1513, April 2025.
Xufei Yang +3 more
wiley +1 more source
The Importance of Liver‐Lung Communication in Pulmonary Vascular Diseases
Comprehensive Physiology, Volume 16, Issue 2, April 2026.Schematic depicting the key drivers of liver‐lung communication in pulmonary vascular diseases, including hepatic dysfunction, portosystemic shunting, and gut microbial dysbiosis, which together drive pulmonary vascular remodeling. ABSTRACT In normal health, the liver and lungs enjoy a close anatomic, physiologic, and functional relationship.
Navneet Singh +8 more
wiley +1 more source
Study on the Effect of Immunosuppressive Agent FK506 on Growth and Migration of Lung Cancer Cell
Chinese Journal of Lung Cancer, 2017 Background and objective FK506, also named tacrolimus, a new macrolide immunosuppressive agent, has been shown to possess anti-proliferation activities in some cancer cells.
Yongwen LI +7 more
doaj +1 more source
FK506 in solid organ transplantation [PDF]
, 1995 FK506 (Prograf) is a new immunosuppressive agent, recently approved for use in solid organ transplants. The first use of FK506 was for the indication of refractory liver allograft rejection.
Fung, JJ, Starzl, TE
core +1 more source
British Journal of Pharmacology, Volume 183, Issue 7, Page 1313-1340, April 2026.Abstract Chronic pain, marked by nociceptive sensitization and maladaptive neuroplasticity, affects 30% of the global population with escalating socioeconomic burdens. Epidemiological data show a 2‐3‐fold increase in neuropsychiatric co‐morbidities among individuals with chronic pain, where epigenetic dysregulation serves as a key mechanism linking ...
Kai Zhang +18 more
wiley +1 more source
Dermal Delivery of the High-Molecular-Weight Drug Tacrolimus by Means of Polyglycerol-Based Nanogels [PDF]
, 2019 Polyglycerol-based thermoresponsive nanogels (tNGs) have been shown to have excellent skin hydration properties and to be valuable delivery systems for sustained release of drugs into skin.
Blume-Peytavi, Ulrike +8 more
core +4 more sources
Advanced Science, Volume 13, Issue 16, 18 March 2026.A post‐stroke perivascular niche of microglia characterized by low expression of M2 markers and elevated glycolysis, oxidative phosphorylation (OXPHOS), and phagocytic activity is identified, which is termed stroke‐activated vascular‐associated microglia (stroke‐VAM).
Yanan Li +8 more
wiley +1 more source
PLoS ONE, 2013 We describe a procedure for the conjugative transfer of phage P1-derived Artificial Chromosome (PAC) library clones containing large natural product gene clusters (≥70 kilobases) to Streptomyces coelicolor strains that have been engineered for improved ...
Adam C Jones +5 more
doaj +1 more source
Effects of tacrolimus on autophagy protein LC3 in puromycin-damaged mouse podocytes
Journal of International Medical Research, 2020 Objective To investigate the mechanism through which tacrolimus, often used to treat refractory nephropathy, protects against puromycin-induced podocyte injury.
Xiao-qing Yang +6 more
doaj +1 more source