Results 171 to 180 of about 4,417 (197)

Echinocandin tolerance and persistence <i>in vitro</i> are regulated by calcineurin signaling in <i>Candida glabrata</i>. [PDF]

mBio
Harrington AA, Nickels TJ, Cunningham KW.   +2 more
europepmc   +1 more source

Anidulafungin is a useful surrogate marker for predicting in vitro susceptibility to rezafungin among five Candida species using CLSI methods and interpretive criteria. [PDF]

J Clin Microbiol
Winkler ML, Deshpande L, Kimbrough JH, Karr M, Rhomberg P, Klauer AL, Castanheira M.   +6 more
europepmc   +1 more source

Identification, antifungal resistance, and genomic characterization of a single <i>Candida auris</i> isolate from urinary tract infection. [PDF]

Front Cell Infect Microbiol
Li J, Wang Z, Zheng R, Wang Y, Guo X, Li X, Zhang P.   +6 more
europepmc   +1 more source

Genome-Wide Analysis of Callose Synthase (CALS) Genes in Cabbage (<i>Brassica oleracea</i> var. <i>capitata</i> L.): Identification and Expression Profiling During <i>Hyaloperonospora parasitica</i> Infection. [PDF]

Int J Mol Sci
Li J, Wu Y, Yao X, Yang L, Zhuang M, Lv H, Wang Y, Ji J, Zhang Y.   +8 more
europepmc   +1 more source

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Echinocandin Resistance in Candida auris Occurs in the Murine Gastrointestinal Tract Due to FKS1 Mutations

Antimicrobial Agents and Chemotherapy, 2023
Candida auris is resistant to multiple antifungal agents. This study investigated its antifungal susceptibility and explored FKS1 mutations across the isolates from mice enterically colonized with wild-type C.
T. Hirayama, T. Miyazaki, Makoto Sumiyoshi, Y. Ito, N. Ashizawa, K. Takeda, N. Iwanaga, T. Takazono, Kazuko Yamamoto, K. Izumikawa, K. Yanagihara, K. Makimura, K. Tsukamoto, S. Kohno, H. Mukae   +14 more
semanticscholar   +3 more sources

Targeting Fks1 proteins for novel antifungal drug discovery.

Trends in Pharmacological Sciences
Fungal infections are a major threat to human health. The limited availability of antifungal drugs, the emergence of drug resistance, and a growing susceptible population highlight the critical need for novel antifungal agents.
Vinit Kumar, Juan Huang, Yawen Dong, Ge-fei Hao   +3 more
semanticscholar   +3 more sources

Analysis of fks1 and fks2 gene mutations in invasive Candida glabrata strains from Pakistan

Mycoses, 2022
The gradual increase in caspofungin usage in Pakistan raises a concern of emergence of echinocandin resistance in local Candida glabrata strains. We sequenced and determined mutations in fks1 and fks2 genes in invasive Candida glabrata strains from ...
S. Memon, N. Ghanchi, Urooj Zafar, J. Farooqi, S. Zaka, K. Jabeen   +5 more
semanticscholar   +3 more sources