We previously reported that flagellin-expressing Pseudomonas aeruginosa (Pa) provokes NEU1 sialidase-mediated MUC1 ectodomain (MUC1-ED) desialylation and MUC1-ED shedding from murine lungs in vivo.
Avelino C. Verceles+11 more
doaj +1 more source
Characterization of structural and immunological properties of a fusion protein between flagellin from Salmonella and lumazine synthase from Brucella [PDF]
Aiming to combine the flexibility of Brucella lumazine synthase (BLS) to adapt different protein domains in a decameric structure and the capacity of BLS and flagellin to enhance the immunogenicity of peptides that are linked to their structure, we ...
Berguer, Paula Mercedes+11 more
core +2 more sources
Generation and selection of anti-flagellin monoclonal antibodies useful for serotyping Salmonella enterica [PDF]
In developing countries, bacterial acute gastroenteritis continues to be an important cause of morbidity and mortality among young children. Salmonellosis constitutes a major cause of infectious enteritis worldwide, most of them associated to the ...
Algorta, Gabriela+8 more
core +2 more sources
Plants have a sensitive perception system for the most conserved domain of bacterial flagellin.
The flagellum is an important virulence factor for bacteria pathogenic to animals and plants. Here we demonstrate that plants have a highly sensitive chemoperception system for eubacterial flagellins, specifically targeted to the most highly conserved ...
G. Felix+3 more
semanticscholar +1 more source
The phytopathogenic bacterium Ralstonia solanacearum requires motility for full virulence, and its flagellin is a candidate pathogen-associated molecular pattern that may elicit plant defenses. Boiled extracts from R.
Christine Pfund+6 more
doaj +1 more source
Glycosidase and glycan polymorphism control hydrolytic release of immunogenic flagellin peptides
Glycosylation goes back and forth Plants produce receptors that recognize fragments of microbial flagellin, thus monitoring for infection by bacteria. Buscaill et al.
Pierre Buscaill+10 more
semanticscholar +1 more source
Flagellin Encoded in Gene-Based Vector Vaccines Is a Route-Dependent Immune Adjuvant. [PDF]
Flagellin has been tested as a protein-based vaccine adjuvant, with the majority of studies focused on antibody responses. Here, we evaluated the adjuvant activity of flagellin for both cellular and humoral immune responses in BALB/c mice in the setting ...
Hamada F Rady+4 more
doaj +1 more source
FliI6-FliJ molecular motor assists with unfolding in the type III secretion export apparatus [PDF]
The role of rotational molecular motors of the ATP synthase class is integral to the metabolism of cells. Yet the function of FliI6-FliJ complex - homologous to the F1 ATPase motor - within the flagellar export apparatus remains unclear. We use a simple two-state model adapted from studies of linear molecular motors to identify key features of this ...
arxiv +1 more source
Halobacterial flagellins are sulfated glycoproteins.
The cell-surface glycoprotein of Halobacteria contains oligosaccharides of the type Glc4----1GlcA4----1GlcA4----1GlcA (where GlcA indicates glucuronic acid) with a sulfate group attached to each of the GlcA residues. We report here that in addition to this cell-surface glycoprotein, the halobacterial flagellar proteins (recently described by Alam, M ...
Wieland, F., Pauli, G., Sumper, Manfred
openaire +4 more sources
Rapid Preparation of Unsheathed Bacterial Flagella
The flagellum is required for bacterial swimming and swarming motility. In the biphasic Salmonella enterica serovar Typhimurium (S. Typhimurium), the flagellar filament is build up by two distinct monomeric subunits, flagellin FliC and FljB.
Soazig Le Guyon+2 more
doaj +1 more source