Results 211 to 220 of about 517,787 (283)

Fn14 signalling participates in pristane‐induced murine lupus through exacerbating oxidative stress

British Journal of Pharmacology, EarlyView.
Background and Purpose Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by oxidative stress and immune dysregulation. Fibroblast growth factor‐inducible 14 (Fn14) has been implicated in tissue injury, but its specific role in SLE pathogenesis remains unclear.
Zhu Yan, Rongfang Feng, Mai Luo, Yaqi Wang, Min Gao, Qin Chen, Yufei Zhang, Yale Liu, Yumin Xia   +8 more
wiley   +1 more source

Structural Modification and Development of <i>N</i>-(1,2,3,4-Tetrahydro-3-isoquinolinylmethyl)benzamide, BPR1M492, as a Potent and Rapid-Onset Opioid Analgesic with Reduced Withdrawal Symptoms. [PDF]

J Med Chem
Chang PW, Chang YC, Tien YW, Chang HF, Chen SR, Chen YP, Huang WC, Hsieh CC, Chang L, Zhuang H, Yeh TK, Tung CW, Yeh SH, Ueng SH.   +13 more
europepmc   +1 more source

High‐Gloss SVBRDF Capture Using Bounce Light

Computer Graphics Forum, EarlyView.
Abstract Reflectance capture aims at the visual reproduction of an object under varying illumination. Past works differ substantially in their experimental overhead, from single‐ or few‐image approaches, that employ significant (often learned) priors at the expense of biased reconstructions, to more accurate approaches that tend to be time‐consuming ...
Tomáš Iser, Andrei‐Timotei Ardelean, Tim Weyrich   +2 more
wiley   +1 more source

Visualization Guidelines for the Control Room: An Evaluation of Visual Alert Encoding with Domain Experts

Computer Graphics Forum, EarlyView.
Abstract Visualization is routinely used in control rooms to maintain situational awareness of complex sociotechnical systems. While control room design often incorporates human factors engineering to identify the information presented, it is not unusual for control room visual encodings to rely closely on operator experience and historical encodings ...
P. Baudains, A.I. Meso, G. Todeschini, R. Borgo   +3 more
wiley   +1 more source

Ultra-high dose rate electron FLASH beam irradiation using a modified clinical linear accelerator. [PDF]

PLoS One
Cho GS, Kim KT, Lee SS, Kim JH, Lee DH, Chang HS, Choi SH, Kim KB, Yang TK, An DH, Kim GB, Kang KU, Kang JK, Kim EJ, Paik EK, Kim MS, Jang WI, Yang KM.   +17 more
europepmc   +1 more source

Heat Stress Triggers Nuclear Invagination and Spatial Compartmentalization of Protein Metabolism

Cell Proliferation, EarlyView.
Cells adapt heat stress to shape a nuclear invagination region function as “protein metabolism hotspots”, where both protein production and degradation are enhanced. ABSTRACT Heat stress is a common challenge for cells, causing multiple types of cellular damage while triggering complex stress responses, including the highly conserved mechanism known as
Zhi‐Hao Zhang, Yuan‐Tao Qiu, Jing‐Yue Cao, Yi‐Feng Huang, Ye‐Lin Lan, Yu‐Li Zhao, Fu Wu, Chen‐Long Wang, Guo‐Run Tang, Jing‐Yun Ji, Zhang Zhang, Guan‐Zheng Luo   +11 more
wiley   +1 more source

Radiobiological and Clinical Advantages of Proton Therapy in Modern Cancer Treatment. [PDF]

Cancers (Basel)
Kalospyros SA, Gkikoudi A, Koutsostathis A, Adamopoulou A, Vasilopoulos SN, Rangos V, Stylianou-Markidou E, Pantalos I, Koumenis C, Georgakilas AG.   +9 more
europepmc   +1 more source

Mind the gap: Ongoing inequalities in glycaemic levels in young people living with Type 1 diabetes across England and Wales

Diabetic Medicine, EarlyView.
Inequalities in glycaemic outcomes for young people living with Type 1 Diabetes in England and Wales. Abstract Aims Inequalities in glycaemic levels in children and young people (CYP) living with Type 1 diabetes (T1D) across different ethnic and socio‐economic groups in England and Wales were first highlighted in 2016.
Victoria Homer, Cillian Brophy, Robert French, Amani Krayem, Saira Pons Perez, Justin T. Warner, Renuka P. Dias   +6 more
wiley   +1 more source

Fiber-Tip Surface-Micromachined Optical Ultrasound Transducer (SMOUT) Probe for Acoustic Detection Induced by Ultrahigh Dose Rate (UHDR) Electron Beam. [PDF]

IEEE Sens J
Fang C, Li B, Litzenberg DW, El Naqa I, Zhang W, Wang X, Zou J.   +6 more
europepmc   +1 more source

Clustering of technological attitudes and reasons for device (non‐)uptake among Dutch people with type 1 diabetes, family members and health professionals

Diabetic Medicine, EarlyView.
Abstract Background Pump and sensor technology contributes to glucose management and quality of life for people with type 1 diabetes (PWD). However, not everyone uses these technologies. This commonly relates to technological attitudes, experiences and expectations. Also, parents and partners (P/P) and healthcare providers (HCPs) may impactful decision‐
M. Horsselenberg, J. B. Prins, M. Boenink, H. J. Aanstoot, G. Nefs   +4 more
wiley   +1 more source