Results 201 to 210 of about 517,787 (283)

A Comparative Study of Directed Energy Deposition‐Arc and Casting: Enhancing Mechanical and Thermal Properties of Hot‐Work Tool Steels

steel research international, EarlyView.
The study investigates the influence of DED‐Arc/M versus casting on the microstructure and material properties of X40CrMoV5‐1 (AISI H13) hot‐work tool steel. DED‐Arc/M yields finer microstructures, superior mechanical strength, and ductility, but slightly reduced thermal conductivity.
Ulf Ziesing, Aaron Berger, Hendric Schaefer, Sebastian Weber, Jonathan Lentz   +4 more
wiley   +1 more source

Identification of Continuous Glucose Monitoring Self-Management Structured Education Programs for People with Type 1 Diabetes Mellitus: A Mixed Methodology Systematic Review. [PDF]

Diabetes Metab Syndr Obes
Pizirtzidou E, Karagkounis C, Bellali T, Katsiki N, Kazakos K, Muzurović E, Minasidou E.   +6 more
europepmc   +1 more source

immunoHuMiX: A personalizable gut‐on‐chip model for unraveling human microbiome–immune interactions

VIEW, EarlyView.
The study introduces a personalized gut model that brings together human immune cells and intestinal cells to better mimic how the body interacts with microbes. This system successfully maintained both human cells and a 17‐strain probiotic community, showing consistent immune responses across different donors.
Charlotte De Rudder, Kacy Greenhalgh, Joanna Baginska, Camille Martin‐Gallausiaux, Léa Grandmougin, Rémy Villette, Mara Lucchetti, Bérénice Hansen, Marek Ostaszewski, Viacheslav A. Petrov, Koji Atarashi, Lena Weidert, Audrey Frachet Bour, Dominik Ternes, Javier Ramiro‐Garcia, Antoine Malabirade, Takeshi Tanoue, Marc Mac Giolla Eain, Elisabeth Letellier, Matthew Barrett, Jérôme Lacombe, Frederic Zenhausern, Coralie Guérin, Markus Ollert, Carole Seguin‐Devaux, Kenya Honda, Paul Wilmes   +26 more
wiley   +1 more source

A high-precision image-guided platform for studying spinal cord toxicity under ultra-high dose rate electron irradiation. [PDF]

Phys Med Biol
Zhou B, Guo L, Tsai YC, van der Kogel A, Wong JW, Iordachita I, Jiang K, Lu W, Medin PM, Wang KK.   +9 more
europepmc   +1 more source

Effect of oxygen and nanoparticles on human skin and colon cells exposed to synchrotron‐based X‐ray FLASH beams

Journal of Synchrotron Radiation, EarlyView.
Most cancer patients will be treated by radiotherapy, and recent findings suggest that delivering radiation at `FLASH' ultra‐high dose rates reduces damage to healthy tissues while still damaging the tumour. This project experimentally validates the reduced healthy tissue damage of FLASH radiotherapy on cells using synchrotron‐based beams, which will ...
Moshi Geso, Matthew Cameron, Tom Ffrench, Helen Forrester, Rod Lynch, Masao Nakayama, William Patterson, Wan Nordiana Rahman, Duncan Butler, Terrence J. Piva   +9 more
wiley   +1 more source

Development and validation of a novel pulse optimization and beam control system for conventional and ultra high dose-per-pulse (FLASH) irradiation. [PDF]

Med Phys
Connell L, Esplen N, Lim R, Baikalov A, Coupey N, Nguyen C, Schüler E.   +6 more
europepmc   +1 more source

Comprehensive Quantification of Oligoasthenozoospermia Induced by Obesity, Reproductive Toxicants, and Their Combination in Rat Models

Andrology, EarlyView.
ABSTRACT Background Oligoasthenozoospermia is a leading cause of male infertility and has been increasingly associated with the global surge in obesity and exposure to reproductive toxicants. Despite extensive research on each factor individually, their combined pathological effects remain poorly understood.
Yunlong Yao, Xi Zhang, Lingru Li, Yunzhi Zhang, Shuo Huang, Yulin Zong, Mingrui Li, Fufangyu Zhao, Linghui Zhu, Tianxing Li, Wenlong Sun, Mingyan Shao, Yanfei Zheng   +12 more
wiley   +1 more source

The Functional Role and Molecular Characterization of the Therapeutic Target CLDN6 in Germ Cell Tumors

Andrology, EarlyView.
ABSTRACT Background The tight junction protein CLDN6 has been identified as a cancer‐associated cell surface marker that is rarely expressed in healthy tissues. In testicular germ cell tumors (GCT), CLDN6 is particularly detectable in seminomas, embryonal carcinomas, and choriocarcinomas.
Jule Zwick, Margaretha A. Skowron, Gereon Poschmann, Patrick Petzsch, Ann Kathrin Bergmann, Kai Stühler, Jochen Hecht, Daniel Nettersheim   +7 more
wiley   +1 more source

FLASH Radiotherapy in Lung Cancer: Translational Mechanisms, Preclinical Evidence, and Barriers. [PDF]

Cureus
Abraham M, Nashwan AJ.
europepmc   +1 more source

Identification and functional validation of a novel disease‐causing variant in the noncoding region of NYX

Acta Ophthalmologica, EarlyView.
Abstract Purpose Inherited retinal diseases (IRDs) are a clinically and genetically heterogeneous group of disorders, with ~30% of cases remaining genetically unsolved. Complete congenital stationary night blindness (cCSNB) is a subtype of IRD, usually associated with reduced visual acuity, nystagmus and high myopia.
Filip Spanic, Christelle Michiels, Julien Navarro, Aline Antonio, Christel Condroyer, Camille Andrieu, Billy Gipsy, Sylvie Berthémy‐Pellet, Mathilde Gallice, Isabelle Audo, Christina Zeitz   +10 more
wiley   +1 more source