Results 181 to 190 of about 698,242 (242)

Advancing Sustainable Development Through Resource Efficiency: Institutional Asymmetries and Firm Capabilities in European Agri‐Food SMEs

Sustainable Development, EarlyView.
ABSTRACT Resource efficiency has become a priority for the European agri‐food sector, yet adoption remains uneven across countries and firms. This study examines how European agri‐food small and medium‐sized enterprises (SMEs) adopt resource efficiency practices.
Luisa Marti, Consuelo Calafat, Nuria Chaparro‐Banegas, Norat Roig‐Tierno   +3 more
wiley   +1 more source

Global clinical landscape and multidisciplinary translational frontiers of FLASH radiotherapy: a systematic review and visualized bibliometric mapping based on WoSCC and PubMed (2014-2025). [PDF]

Front Med (Lausanne)
Di Y, Liu C, Wang Y, Cai B, Meng L.
europepmc   +1 more source

Context‐Dependent Radioenhancement by Platinum Nanoparticles Under Conventional and Ultra‐High Dose‐Rate “FLASH” Radiotherapy

Small, EarlyView.
Overview of the experimental workflow and main findings of the study investigating Pt‐NPs‐mediated radioenhancement under conventional 134 dose‐rate (CONV) and ultrahigh dose‐rate (UHDR) 9 MeV electron irradiation. Pt‐NP distribution and uptake were characterized in 4T1 spheroids and syngeneic tumor models.
Cathyanne Schott, Foutina Feghali, Marine Gerbé de Thoré, Amina Joudat, Lydia Meziani, Aashini Rajpal, Winchygn Liu, Tudor Manoliu, Farah Savina, Sandrine Lacombe, Eric Deutsch, Julie Colnot, Charlotte Robert, Erika Porcel, Pauline Maury   +14 more
wiley   +1 more source

3D Nanoprinted Structures Promote Robust Integration of Brain Organoids into Topography‐Guided Neuronal Networks

Small, EarlyView.
Dedicated cultivation platforms facilitate the implementation of brain organoids in guided neuronal networks. Fabrication is enabled by two‐photon polymerization‐based 3D nanoprinting (3DN) and allows for cultivation in standard 12‐well plates. Fine features, namely slopes, funnels, rods, steps, and walls, facilitate and promote organoid positioning ...
Malte Siegmund, Tobias Müller, Emma Wollesen, Kim Krieg, Jack Muse, Jan Hahn, Maya Luongo, Wolfgang J. Parak, Ole Pless, Robert Zierold, Robert H. Blick   +10 more
wiley   +1 more source

Precise delineation of radiation targets for thoracic tumors in the immunotherapy era: From immune mechanisms to clinical practice. [PDF]

Precis Radiat Oncol
Chen X, Yi M, Deng Y, Shen Q.
europepmc   +1 more source

A Cytoplasmic pH Sensor Redefines Gating in Bacterial Urea Channels and Acid Resistance

Small, EarlyView.
Bacterial survival in acidic environments requires pH‐gated urea channels. Utilizing complementary approaches, we identify a conserved cytoplasmic glutamic acid residue as a pH sensor in UreI channels. Whereas Gram‐positive bacteria rely solely on this sensor, Gram‐negative bacteria employ a dual‐sensor mechanism with periplasmic residues, revealing a ...
Anna Stoib, Sahar Shojaei, Xenia Fischer, Sandra Posch, Gianluca Parisse, Mario Frezzini, Tobias Putz, Christine Siligan, Nikolaus Goessweiner‐Mohr, Daniele Narzi, Andreas Horner   +10 more
wiley   +1 more source

Ultra-high-dose-rate pulsed irradiation and the conditional FLASH effect: dosimetry, multiscale biology, and clinical translation. [PDF]

Front Oncol
Zhang J, Lu H, Dong G, Wang C.
europepmc   +1 more source

Endocytosis‐independent cytosolic entry of messenger RNA via fluorous bilayer zippering attenuating Toll‐like receptor signaling and enables ischemic tissue salvage

Smart Molecules, EarlyView.
The present study establishes a paradigm shift in synthetic mRNA delivery through the convergence of three orthogonal chemistries—perfluoro‐acylation, bio‐orthogonal click cross‐linking, and disulfide reduction—within a single, modular polymer architecture. Abstract A fundamental constraint of conventional messenger RNA (mRNA) delivery systems is their
Yue Wang, Haitao Xie, Guoqing Xiang, Yanhua Li, Changgui Tong, Hongyan Cui, Qixian Chen, Haidong Li, Yan Zhao   +8 more
wiley   +1 more source

Early microglial activation in the TME enables FLASH-RT to eradicate medulloblastoma while promoting neuron-astrocyte crosstalk to minimize toxicity in the hippocampus

Knol M, Franco-Pérez J, Almeida A, Kunz LV, Petit B, Job A, Ollivier J, Romero J, Jansen J, Grilj V, Limoli C, Vozenin M, Ballesteros-Zebadúa P.   +12 more
europepmc   +1 more source

Towards FLASH Radiotherapy in Lung Cancer: A Review on Preclinical Evidence and Technical Feasibility. [PDF]

Cancers (Basel)
Visser SN, Habraken SJM, Puspitasari-Kokko A, Zur Horst AH, Rasch CRN, van Doorn-Wink KCJ.   +5 more
europepmc   +1 more source