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The pharmacokinetics of flavanones
Critical Reviews in Food Science and Nutrition, 2019The intake of flavanones, the predominant flavonoid in the Citrus genus in human diets is variable but considerable. It is thus unsurprising that they have attracted interest for their claimed positive effects on health. However, to substantiate any purported impact on health and decipher the underlying mechanism(s), knowledge of pharmacokinetics is ...
Iveta Najmanová +3 more
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Selective Halogenation of Flavanones.
ChemInform, 2002AbstractFor Abstract see ChemInform Abstract in Full Text.
Bovicelli P +3 more
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The photochemistry of flavanone
Journal of the Chemical Society, Chemical Communications, 1972On u.v. irradiation, flavanone rearranges to 4-phenyldihydrocoumarin and 2′-hydroxychalcone, and undergoes fragmentation to yield a highly reactive keto-keten.
P. O. L. Mack, J. T. Pinhey
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An Improved Method for the Synthesis of Flavanones
Russian Journal of Bioorganic Chemistry, 2002An isomerization of 2'-hydroxychalcones into the corresponding flavanones in ethanol in the presence of triethylamine is described.
A, Aĭtmambetov, A A, Kubzheterova
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Enzymatic halogenation of flavanones and flavones
Phytochemistry, 2001The whole cells and the chloroperoxidase enzyme of Caldariomyces fumago were capable of halogenating the flavanones, naringenin and hesperetin, at C-6 and C-8 in the presence of either Cl- or Br-. However, they did not act on other test flavones. The biohalogenated products of naringenin and hesperetin were isolated and found to be identical to those ...
P, Yaipakdee, L W, Robertson
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Efficient Synthesis of Flavanone Glucuronides
Journal of Agricultural and Food Chemistry, 2009The first efficient synthesis of flavanone glucuronides as potential human metabolites is described. The synthetic strategy is based on acetyl protection, followed by a combination of chemical and enzymatic deprotection steps. As an example, the method is applied to a synthesis of 7,4'-di-O-methyleriodictyol 3'-O-beta-d-glucuronide.
Ahcene, Boumendjel +3 more
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The biliary excretion of flavanones in the rat
Xenobiotica, 19791. The major biliary metabolites of flavanones in the rat have been identified by chromatographic and spectral methods. 2. Evidence is presented that flavanones and flavanone glycosides, following oral or parenteral administration, undergo glucuronylation and are selectively excreted via the bile. 3.
A M, Hackett +3 more
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Microbiological Transformation of (±)-Flavanone and (±)-Isoflavanone
Journal of Natural Products, 1990The microbiological transformation of flavanone and isoflavanone was explored using a group of 80 microorganisms in the initial screening. Ten metabolites of flavanone were isolated and identified as 4'-hydroxyflavanone [3], 3',4'-dihydroxyflavanone [4], 3-hydroxyflavone [2], flavone [5], 2'-hydroxydihydrochalcone [7], 2',4-dihydroxydihydrochalcone [6],
A R, Ibrahim, Y J, Abul-Hajj
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