Results 111 to 120 of about 111,183 (286)

Escherichia coli Fails to Efficiently Maintain the Activity of an Important Flavin Monooxygenase in Recombinant Overexpression

open access: yesFrontiers in Microbiology, 2017
This paper describes the measurement and analysis of in vivo activity and stability of cyclohexanone monooxygenase from Acinetobacter sp. NCIMB 9871 (CHMO), a model Baeyer–Villiger monooxygenase, in the recombinant host Escherichia coli.
Sofia Milker   +4 more
doaj   +1 more source

DNA-Mediated Electrochemistry [PDF]

open access: yes, 2008
The base pair stack of DNA has been demonstrated as a medium for long-range charge transport chemistry both in solution and at DNA-modified surfaces. This chemistry is exquisitely sensitive to structural perturbations in the base pair stack as occur with
Barton, Jacqueline K.   +2 more
core   +2 more sources

An Orthogonal Way of Writing the Tubulin Code

open access: yesCytoskeleton, EarlyView.
ABSTRACT The Elongator complex has long been characterized for its role in tRNA modification and modulation of protein translation. Beyond these established functions, recent findings reveal an unexpected role for Elongator in directly interacting and tuning microtubule dynamics and properties, broadening its biological significance in eukaryotic cells.
Vicente Jose Planelles‐Herrero   +1 more
wiley   +1 more source

Electrochemical Comparative Study of Riboflavin, FMN and FAD Immobilized on the Silica Gel Modified with Zirconium Oxide

open access: yesJournal of the Brazilian Chemical Society, 2002
Modified carbon paste electrodes were prepared by the adsorption of flavin on a silica gel modified with zirconium oxide (Si:Zr:flavin). The electrochemical behavior of immobilized riboflavin, FMN and FAD was investigated.
Yamashita Miyuki   +2 more
doaj  

Expression, Purification, and Microscopy‐Based Assays for Engineered Recombinant Tyrosinated, Detyrosinated, and Δ2 Human Tubulin

open access: yesCytoskeleton, EarlyView.
ABSTRACT Microtubules are noncovalent polymers assembled from α/β tubulin dimers. Their structure, dynamics and interaction with effectors are regulated through the expression of diverse tubulin isotypes and chemically diverse posttranslational modifications, also known as the “tubulin code.” Understanding the biophysical correlates between tubulin ...
Jiayi Chen   +2 more
wiley   +1 more source

Stimuli-Responsive Luminescence of an Amphiphilic Flavin Derivative via Thermodynamic and Kinetic Aggregation in Water

open access: yesPhotochem
In this study, we investigated environmentally responsive photoluminescence color changes in water using an amphiphilic flavin derivative (1a) functionalized with an alkylsulfonate group.
Soichiro Kawamorita   +3 more
doaj   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler   +4 more
wiley   +1 more source

Flavin-tag

open access: yes, 2023
Site-specific protein labeling plays a core role in investigating protein function at molecular level. A multitude of protein labelling techniques has been developed which are based on chemical and/or enzymatic methods. Enzyme-based labeling of proteins typically relies on a specific peptide sequence (a “tag”) that can be recognized and modified by a ...
openaire   +1 more source

Epigenotoxicity: Decoding the epigenetic imprints of genotoxic agents and their implications for regulatory genetic toxicology

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Regulatory genetic toxicology focuses on DNA damage and subsequent gene mutations. However, genotoxic agents can also affect epigenetic marks, and incorporation of epigenetic data into the regulatory framework may thus enhance the accuracy of risk assessment.
Roger Godschalk   +4 more
wiley   +1 more source

Crystal Structures of Putative Flavin Dependent Monooxygenase from Alicyclobacillus Acidocaldarius

open access: yesCrystals, 2019
Flavin dependent monooxygenases catalyze various reactions to play a key role in biological processes, such as catabolism, detoxification, and biosynthesis.
Hyunjin Moon   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy