Results 61 to 70 of about 9,389 (177)

Comparing Early Graft Dysfunction Scores in Liver Transplantation After Ex‐Situ Normothermic Machine Perfusion

Clinical Transplantation, Volume 40, Issue 8, August 2026.
ABSTRACT Introduction As normothermic machine perfusion (NMP) maintains liver grafts in a near‐physiologic state, uncoupling ischemia–reperfusion injury from the recipient, the validity of early graft dysfunction scores from the static cold storage (SCS) era are uncertain.
Kejal Shah, Sydney Castellanos, April J. Logan, Leonid Gorelik, Annelise Nolan, Manoj Iyer, Lauren Von Stein, Wei Chen, Ayato Obana, Ashley Limkemann, Navdeep Singh, Sylvester Black, William K. Washburn, Austin D. Schenk, Musab Alebrahim, Sai Rithin Punjala   +15 more
wiley   +1 more source

Riboflavin Salvage Supports Glycolysis in Borrelia burgdorferi Through Flavin‐Dependent NAD+ Regeneration

Molecular Microbiology, Volume 126, Issue 2, Page 208-219, August 2026.
The Lyme disease agent Borrelia burgdorferi has limited metabolic capabilities and depends on salvage of riboflavin via the BB0316‐BB0319 transport system for generation of critical flavin cofactors FMN and FAD. Riboflavin is important for NAD+ regeneration to fuel glycolysis.
Anna M. Schulz, Grace E. Easterling, Aaditya Balasubramaniyan, Mollie W. Jewett   +3 more
wiley   +1 more source

Safety and efficacy of a feed additive consisting of nicarbazin (NICACOX®) for chickens for fattening and chickens reared for laying (Huvepharma N.V.)

EFSA Journal, Volume 24, Issue 8, August 2026.
Abstract Following a request from the European Commission, EFSA was asked to deliver a scientific opinion on the safety and efficacy of a feed additive consisting of nicarbazin (NICACOX®) as a coccidiostat for chickens for fattening and chickens reared for laying.
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP), Roberto Edoardo Villa, Giovanna Azimonti, Eleftherios Bonos, Henrik Christensen, Mojca Durjava, Birgit Dusemund, Ronette Gehring, Boet Glandorf, Maryline Kouba, Marta López‐Alonso, Francesca Marcon, Giovanna Martelli, Carlo Nebbia, Alena Pechová, Miguel Prieto‐Maradona, Katerina Theodoridou, Georges Bories, Paul Brantom, Jürgen Gropp, Guido Rychen, Luca Tosti, Ruud Woutersen, Jaume Galobart, Fabiola Pizzo, Alberto Navarro‐Villa, Maria Vittoria Vettori, José Cortiñas Abrahantes, Orsolya Holczknecht   +28 more
wiley   +1 more source

The RFK catalytic cycle of the pathogen Streptococcus pneumoniae shows species-specific features in prokaryotic FMN synthesis

Journal of Enzyme Inhibition and Medicinal Chemistry, 2018
Emergence of multidrug-resistant bacteria forces us to explore new therapeutic strategies, and proteins involved in key metabolic pathways are promising anti-bacterial targets.
María Sebastián, Adrián Velázquez-Campoy, Milagros Medina   +2 more
doaj   +1 more source

Structural and functional investigation of flavin binding center of the NqrC subunit of sodium-translocating NADH:quinone oxidoreductase from Vibrio harveyi.

PLoS ONE, 2015
Na+-translocating NADH:quinone oxidoreductase (NQR) is a redox-driven sodium pump operating in the respiratory chain of various bacteria, including pathogenic species.
Valentin Borshchevskiy, Ekaterina Round, Yulia Bertsova, Vitaly Polovinkin, Ivan Gushchin, Andrii Ishchenko, Kirill Kovalev, Alexey Mishin, Galina Kachalova, Alexander Popov, Alexander Bogachev, Valentin Gordeliy   +11 more
doaj   +1 more source

Azurins With Tunable Reduction Potentials as Redox Mediators for Extracellular Electron Transfer

ChemBioChem, Volume 27, Issue 14, 29 July 2026.
Electroactive microbe Shewanella oneidensis reduced non‐native electron transfer protein, azurin, via extracellular electron transfer (EET) with dependence on azurin redox potential. Utilizing azurin in EET‐driven bio‐(electro)catalysis improved fuel cell current and accelerated textile dye decolorization.
Alexis J. Holwerda, Jing‐Xiang Wang, Yang Gao, Yi Lu, Benjamin K. Keitz   +4 more
wiley   +1 more source

Altered CYP19A1 and CYP3A4 Activities Due to Mutations A115V, T142A, Q153R and P284L in the Human P450 Oxidoreductase

Frontiers in Pharmacology, 2017
All cytochromes P450s in the endoplasmic reticulum rely on P450 oxidoreductase (POR) for their catalytic activities. Mutations in POR cause metabolic disorders of steroid hormone biosynthesis and affect certain drug metabolizing P450 activities.
Sameer S. Udhane, Sameer S. Udhane, Shaheena Parween, Shaheena Parween, Norio Kagawa, Amit V. Pandey, Amit V. Pandey   +6 more
doaj   +1 more source

Hydrolysis of flavin adenine dinucleotide and flavin mononucleotide by rabbit blood.

Journal of Nutritional Science and Vitaminology, 1980
Hydrolysis of FAD and FMN by rabbit blood was studied. The whole blood hydrolyzed both FAD and FMN to riboflavin. Blood plasma hydrolyzed FAD rapidly to FMN, but hydrolyzed FMN slowly to riboflavin. On the other hand, red cells hydrolyzed FAD slowly to FMN, but hydrolyzed FMN rapidly to riboflavin.
OKUMURA, Misao, YAGI, Kunio
openaire   +3 more sources

Kinetic and Spatial Resolution by dSTORM of miniSOG‐Mediated Proximity Labeling in Mammalian Cells

ChemBioChem, Volume 27, Issue 13, 14 July 2026.
Controlled blue‐light illumination defines the kinetic regimes and nanoscale labeling radius of miniSOG in mammalian cells. dSTORM imaging reveals an illumination‐tunable proximal labeling range (∼70–180 nm), establishing quantitative spatial parameters for miniSOG‐mediated photocatalytic tagging and enabling proximity‐labeling strategies.
Benoît Arnould, Alexandria L. Quillin, Aastha, Tatiana F. Flores, Jennifer M. Heemstra   +4 more
wiley   +1 more source

The Photoinactivation of Tobacco Transketolase in the Presence of Flavin Mononucleotide

Zeitschrift für Naturforschung B, 1972
Transketolase from the leaves of Nicotiana tabacum var. John William′s Broadleaf is inhibited by exposure to low intensity blue light in the presence of low concentrations of FMN, which functions as a sensitizer. The degree of photoinactivation is reduced in the presence of quenchers of triplet FMN.
openaire   +2 more sources