Flavoproteins are of key importance to all life on earth for both primary and secondary metabolism. Most flavin-dependent enzymes utilize flavin mononucleotide (FMN) or flavin adenine dinucleotide (FAD) as redox cofactor for single-electron and hydride transfer as well as oxidation and oxygenation chemistry at the C4a-locus.
Drenth, Jeroen, Fraaije, Marco W.
openaire +1 more source
The nitrite anion: the key intermediate in alkyl nitrates degradative mechanism. [PDF]
Alkyl nitrates, _in vivo_, are metabolized to yield nitric oxide, and thiol groups are considered necessary cofactors. This statement is based on studies that underline how these species potentiate hemodynamic responsiveness to nitrates in patients with ...
Loris Grossi
core +1 more source
ABSTRACT Background Porokeratoses represent a group of keratinization disorders characterized histopathologically by the presence of a cornoid lamella. The recognition of porokeratosis as a genodermatosis, along with its association with increased risk of skin cancer, underscores the importance of accurate and timely diagnosis.
Rahime Inci +5 more
wiley +1 more source
Energetics of the Citric Acid Cycle in the Deep Biosphere
This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.
Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions
Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Peter A. Canovas III, Everett L. Shock
wiley +1 more source
Structure and Mechanism of PhdC, a Prenylated‐Flavin Maturase
ABSTRACT Prenylated flavin mononucleotide (prFMN) is a modified flavin cofactor required by the UbiD family of (de)carboxylase enzymes. While the reduced prFMNH2 form is produced by the flavin prenyltransferase UbiX, the corresponding two‐electron oxidized prFMNiminium form is required to support UbiD catalysis. Thus, oxidative maturation of prFMNH2 is
Dominic R. Whittall +4 more
wiley +1 more source
ABSTRACT The promotion of clean energy is critical to achieving sustainable development. This study investigates the factors that affect the exports, trade potential, and revealed comparative advantage (RCA) of clean energy products (CEPs) in the emerging Asian economies (EAEs).
Arvind Goswami +2 more
wiley +1 more source
Nucleotide sequence of the luxA gene of Vibrio harveyi and the complete amino acid sequence of the alpha subunit of bacterial luciferase [PDF]
The nucleotide sequence of the 1.85-kilobase EcoRI fragment from Vibrio harveyi that was cloned using a mixed-sequence synthetic oligonucleotide probe (Cohn, D. H., Ogden, R. C., Abelson, J. N., Baldwin, T. O., Nealson, K. H., Simon, M.
Baldwin, Thomas O. +6 more
core
NQO1‐Responsive Prodrug for in Cellulo Release of Cytochalasin B as Cancer Cell‐Targeted Migrastatic
The design, synthesis, biochemical, and cell biological evaluation of the NQO1‐targeted prodrug BQTML‐CB is reported. BQTML‐CB selectively releases cytochalasin B upon activation by the quinone‐oxidoreductase NQO1 associated with invasiveness of cancer cells, representing a novel approach to improve cancer selectivity and reduce immunosuppressive ...
Mervic D. Kagho +10 more
wiley +1 more source
We present a high‐performance enzymatic biofuel cell based on a micro‐corrugated hydrogel electrode engineered via capillary force and ligand exchange‐induced assembly of tetra(octylammonium) (TOA)‐stabilized Au nanoparticles (Au NPs). The resulting metallic TOA‐Au NPs hydrogel structure enables seamless electron transfer and stable enzyme ...
Eunju Choi +10 more
wiley +1 more source
Redox-active molecules in bacterial cultivation media produce photocurrent
Renewable energy concepts such as microbial fuel cells (MFCs) present a promising, yet intrinsically complex electrochemical approach for utilizing bacteria as an electron source. In this work, we show that just the cultivation media for bacterial growth,
Matthew C. Smith +6 more
doaj +1 more source

