Results 151 to 160 of about 7,181 (257)

Redox signals and oxidative stress in the control of mitochondrial protein import

open access: yesProtein Science, Volume 35, Issue 7, July 2026.
Abstract Mitochondrial protein import is essential for organelle biogenesis and cellular homeostasis. It operates in an environment that is intrinsically shaped by redox chemistry. Mitochondria are major sources of reactive oxygen species (ROS), which arise as by‐products of oxidative phosphorylation. Cells therefore maintain sophisticated ROS‐handling
Lidwina Hasberg   +3 more
wiley   +1 more source

Structure–activity relationship study shows versatility in substrate specificity for heterodisulfide reductase in methanogenic archaea

open access: yesProtein Science, Volume 35, Issue 7, July 2026.
Abstract Hydrogenotrophic methanogens are anaerobic archaea that convert carbon dioxide and hydrogen into methane. Central to this process is the heterodisulfide reductase (Hdr), which catalyzes the reduction of the heterodisulfide made of coenzyme M and coenzyme B. In vivo, Hdr functions in association with electron‐donating modules such as the [NiFe]‐
Mahdi Faal Maleki   +5 more
wiley   +1 more source

Engineering Alloxazines by Boron Coordination and Click Chemistry toward Small-molecule Fluorescent Probes. [PDF]

open access: yesChemistry
Charpentier O   +5 more
europepmc   +1 more source

Integrated genomic and transcriptomic approaches reveal oxidative stress adaptation mechanisms in a mesotrione‐resistant Amaranthus tuberculatus biotype

open access: yesPest Management Science, Volume 82, Issue 7, Page 6387-6398, July 2026.
Integrated GWAS and transcriptomics in a Canadian waterhemp biotype reveal mesotrione resistance is polygenic and metabolically driven. Significant SNPs and 187 herbicide‐responsive genes point to enhanced redox homeostasis, glutathione‐linked detoxification, lipid/secondary metabolism, and oxidative stress responses. Resistance arises from coordinated,
Martin Laforest   +6 more
wiley   +1 more source

Semi‐Rational Engineering of Formate Dehydrogenase Reveals Loop Dynamics as a Key Determinant of Thermostability

open access: yesChemBioChem, Volume 27, Issue 11, 15 June 2026.
Semi‐rational engineering yields a thermostable Bacillus simplex formate dehydrogenase variant (Q125F) with a 25‐fold longer half‐life at 60°C and strong resistance to chemo‐inactivation. Molecular dynamics reveal enhanced π–π interactions stabilizing a flexible loop and enabling efficient NADH regeneration for robust biocatalytic detoxification ...
Rattima Boonkumkrong   +7 more
wiley   +1 more source

Enantioselective Synthesis of Lactic Acid From CO2 Using a Novel Pyruvate Decarboxylase in a Scalable Biocatalytic Cascade

open access: yesAdvanced Synthesis &Catalysis, Volume 368, Issue 11, 3 June 2026.
We report a scalable biocatalytic cascade that converts CO2 and acetaldehyde to pyruvate via a newly characterized pyruvate decarboxylase, followed by stereoselective reduction to lactic acid. The system enables fully switchable enantioselectivity using either L‐ or D‐lactate dehydrogenases.
Silvia Fruncillo   +9 more
wiley   +1 more source

Identification of colorectal malignancies enabled by phasor-based autofluorescence lifetime macroimaging and ensemble learning. [PDF]

open access: yesBiophotonics Discov
Lagarto JL   +10 more
europepmc   +1 more source

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