Results 111 to 120 of about 7,181 (257)

Non‐canonical PKG1 regulation in cardiovascular health and disease

British Journal of Pharmacology, EarlyView.
It is well established that the cyclic GMP‐dependent protein kinase I (PKG1) is canonically activated by cyclic guanosine monophosphate (cGMP), enabling its regulation of vascular tone, cardiac function and smooth muscle homeostasis. However, diverse non‐canonical stimuli of PKG1 have also been identified.
Jie Su, Joseph Robert Burgoyne
wiley   +1 more source

Direct Observation of Franck-Condon Stimulated Emission and Sub-20 fs Relaxation in Photoexcited Flavins. [PDF]

J Phys Chem Lett
Timmer D, Kumar K, Götze JP, Saalfrank P, De Sio A, Lienau C.   +5 more
europepmc   +1 more source

A study on the NAD(P)+ transhydrogenase from Azotobacter vinelandii

, 1975
Azotobacter vinelandii transhydrogenase shows a pronounced polymerizing depolymerizing character (Chapter 3 and 5). Several factors seem to influence this phenomenon.
Krul, J.
core  

THE TREATMENT OF WOUNDS BY FLAVINE [PDF]

BMJ, 1918
E M, Pilcher, A J, Hull
openaire   +2 more sources

Therapeutic potential of small molecules that block receptor‐induced Kv7/M‐current suppression in neuroprotection, seizures, and pain

British Journal of Pharmacology, EarlyView.
Receptor‐induced Kv7/M‐current suppression increases neuronal activity and contributes to pathology of several conditions. A new class of Kv7 modulators identified in this study attenuates M‐current suppression and shows therapeutic effects. Abstract Background and Purpose Neuronal Kv7 channels generate low voltage–gated potassium currents known as the
Young Woo Kim, Pavan Kumar Behara, Lamees Alhassen, Cindy Wong, Olivier Civelli, Naoto Hoshi   +5 more
wiley   +1 more source

Cell-Surface Inter-Cytochrome Electron Transfer Limits Biofilm Electron Conduction Kinetics in <i>Shewanella oneidensis</i>. [PDF]

J Am Chem Soc
Wen X, Long X, Huang W, Kuramochi M, Okamoto A.   +4 more
europepmc   +1 more source

Following Flavin's Vibrational Modes to Probe Anharmonicities and Low-Lying Conical Intersections. [PDF]

J Phys Chem B
Vu V, Gozem S.
europepmc   +1 more source

Idiosyncratic asset return and wage risk of US households

Economic Inquiry, Volume 63, Issue 2, Page 636-657, April 2025.
Abstract This paper documents the degree of idiosyncratic asset return heterogeneity, serial correlation, and correlation with wage heterogeneity for US households. Novel panel‐data measurements for returns on household assets are proposed. Sizable transitory idiosyncratic return heterogeneity is documented to exist concurrently with permanent ...
Stephen Snudden
wiley   +1 more source

The influence of protein electrostatics on potential inversion in flavoproteins. [PDF]

Chem Sci
Singh N, Zhang P, Beratan DN.
europepmc   +1 more source

Tyrosine residues at the substrate binding site in human NQO1 homodimer: Protein conformational dynamics and optimization of substrate binding geometry

The FEBS Journal, EarlyView.
Human NAD(P)H:quinone oxidoreductase 1 is a homodimeric flavoenzyme crucial for redox metabolism and linked to significant health issues. Point mutations at Tyr126 and Tyr128 demonstrate their essential roles in optimizing substrate binding geometry for catalysis, as well as in half‐site reactivity and conformational dynamics during the enzyme's ...
Maribel Rivero, Juan Luis Pacheco‐Garcia, Pavla Vankova, Dmitry Loginov, Isabel Quereda‐Moraleda, Jose Manuel Martin‐Garcia, Petr Man, Angel Luis Pey, Milagros Medina   +8 more
wiley   +1 more source