Methods for Lipid Droplet Biophysical Characterization in Flaviviridae Infections [PDF]
Lipid droplets (LDs) are intracellular organelles for neutral lipid storage, originated from the endoplasmic reticulum. They play an essential role in lipid metabolism and cellular homeostasis.
Ana S. Martins+2 more
doaj +7 more sources
Rewiring cellular networks by members of the Flaviviridae family [PDF]
Members of the Flaviviridae virus family comprise a large group of enveloped viruses with a single-strand RNA genome of positive polarity. Several genera belong to this family, including the Hepacivirus genus, of which hepatitis C virus (HCV) is the ...
C. Neufeldt+3 more
semanticscholar +6 more sources
Molecular Events Occurring in Lipophagy and Its Regulation in Flaviviridae Infection [PDF]
Diseases caused by Flaviviridae have a wide global and economic impact due to high morbidity and mortality. Flaviviridae infection usually leads to severe, acute or chronic diseases, such as liver injury and liver cancer resulting from hepatitis C virus (
Keke Wu+19 more
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ICTV Virus Taxonomy Profile: Flaviviridae
The Flaviviridae is a family of small enveloped viruses with RNA genomes of 9000–13 000 bases. Most infect mammals and birds. Many flaviviruses are host-specific and pathogenic, such as hepatitis C virus in the genus Hepacivirus.
P. Simmonds+10 more
semanticscholar +4 more sources
BackgroundViruses of the family Flaviviridae, including Japanese encephalitis virus (JEV), dengue virus (DENV), yellow fever virus (YFV) and hepatitis C virus (HCV), are widely distributed worldwide.
Ran Wang+6 more
doaj +4 more sources
A New Subclass of Exoribonuclease-Resistant RNA Found in Multiple Genera of
Viruses have developed innovative strategies to exploit the cellular machinery and overcome the antiviral defenses of the host, often using specifically structured RNA elements.
Matthew J. Szucs+4 more
doaj +4 more sources
Flaviviridae Nonstructural Proteins: The Role in Molecular Mechanisms of Triggering Inflammation
Members of the Flaviviridae family are posing a significant threat to human health worldwide. Many flaviviruses are capable of inducing severe inflammation in humans.
Anastasia Latanova+2 more
doaj +2 more sources
Dual-Role Ubiquitination Regulation Shuttling the Entire Life Cycle of the Flaviviridae
Ubiquitination is a reversible protein post-translational modification that regulates various pivotal physiological and pathological processes in all eukaryotes.
Dongjie Cai+12 more
doaj +2 more sources
Mapping glycoprotein structure reveals Flaviviridae evolutionary history. [PDF]
Viral glycoproteins drive membrane fusion in enveloped viruses and determine host range, tissue tropism and pathogenesis1. Despite their importance, there is a fragmentary understanding of glycoproteins within the Flaviviridae2, a large virus family that
Mifsud JCO+6 more
europepmc +2 more sources
Virus-host coevolution: common patterns of nucleotide motif usage in Flaviviridae and their hosts. [PDF]
Virus-host biological interaction is a continuous coevolutionary process involving both host immune system and viral escape mechanisms. Flaviviridae family is composed of fast evolving RNA viruses that infects vertebrate (mammals and birds) and/or ...
Francisco P Lobo+7 more
doaj +17 more sources