Results 1 to 10 of about 36,337 (243)

Dual-Role Ubiquitination Regulation Shuttling the Entire Life Cycle of the Flaviviridae [PDF]

open access: goldFrontiers in Microbiology, 2022
Ubiquitination is a reversible protein post-translational modification that regulates various pivotal physiological and pathological processes in all eukaryotes.
Liuhong Shen, Liping Gou, Zhicai Zuo
exaly   +4 more sources

Flaviviridae Nonstructural Proteins: The Role in Molecular Mechanisms of Triggering Inflammation [PDF]

open access: goldViruses, 2022
Members of the Flaviviridae family are posing a significant threat to human health worldwide. Many flaviviruses are capable of inducing severe inflammation in humans.
Anastasia Latanova   +2 more
doaj   +2 more sources

Virus-host coevolution: common patterns of nucleotide motif usage in Flaviviridae and their hosts. [PDF]

open access: goldPLoS ONE, 2009
Virus-host biological interaction is a continuous coevolutionary process involving both host immune system and viral escape mechanisms. Flaviviridae family is composed of fast evolving RNA viruses that infects vertebrate (mammals and birds) and/or ...
Francisco P Lobo   +7 more
doaj   +3 more sources

Structural Motifs and Spatial Structures of Helicase (NS3) and RNA-dependent RNA-polymerase (NS5) of a Flavi-like Kindia tick virus (unclassified Flaviviridae)

open access: diamondВопросы вирусологии, 2023
Introduction. Kindia tick virus (KITV) is a novel segmented unclassified flavi-like virus of the Flaviviridae family. This virus is associated with ixodes ticks and is potentially pathogenic to humans.
A. A. Gladysheva   +3 more
doaj   +3 more sources

Proteochemometric Method for pIC50 Prediction of Flaviviridae [PDF]

open access: greenBioMed Research International, 2022
Viruses remain an area of concern despite constant development of antiviral drugs and therapies. One of the contributors is the Flaviviridae family of viruses causing diseases that need attention. Among other anitviral methods, antiviral peptides are being studied as viable candidates.
Divye Singh   +3 more
openaire   +3 more sources

Transient receptor potential channels in Flaviviridae infection: A comprehensive review [PDF]

open access: yesChannels
Diseases caused by Flaviviridae viruses exert profound global health and economic burdens due to their high incidence and associated mortality. Infection by the Flaviviridae family often leads to severe acute or chronic illnesses, including hemorrhagic ...
Fuchun Jiang   +2 more
doaj   +2 more sources

Test systems for the laboratory detection and differentiation of Powassan virus from tick-borne encephalitis virus (Flaviviridae: Orthoflavivirus) using RT-PCR and RT-qPCR

open access: diamondВопросы вирусологии
Introduction. Powassan virus (POWV) is a tick-borne orthoflavivirus capable of causing neurological diseases. In the Russian Far East, the area affected by POWV overlaps with that of another neurotropic orthoflavivirus, tick-borne encephalitis virus ...
Maria P. Fedina   +3 more
doaj   +3 more sources

Molecular Events Occurring in Lipophagy and Its Regulation in Flaviviridae Infection

open access: yesFrontiers in Microbiology, 2021
Diseases caused by Flaviviridae have a wide global and economic impact due to high morbidity and mortality. Flaviviridae infection usually leads to severe, acute or chronic diseases, such as liver injury and liver cancer resulting from hepatitis C virus (
Keke Wu, Shuangqi Fan, Linke Zou
exaly   +3 more sources

Shifting Epidemiology of Flaviviridae [PDF]

open access: bronzeJournal of Travel Medicine, 2008
The dengue, West Nile, Japanese encephalitis and yellow fever viruses are important mosquito-borne viruses whose epidemiology is shifting in response to changing societal factors, such as increasing commerce, urbanization of rural areas, and population growth.
Lyle R, Petersen, Anthony A, Marfin
openaire   +3 more sources

Flaviviridae RdRp exploits NSUN2-driven m5C methylation to establish persistent infection. [PDF]

open access: yesPLoS Pathogens
Flaviviridae viruses constitute formidable zoonotic agents with substantial global health and economic ramifications, attributable to their adeptness at circumventing host immune surveillance and establishing persistent infections across human and animal
Jing Chen   +13 more
doaj   +2 more sources

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