Methods for Lipid Droplet Biophysical Characterization in Flaviviridae Infections [PDF]
Frontiers in Microbiology, 2018 Lipid droplets (LDs) are intracellular organelles for neutral lipid storage, originated from the endoplasmic reticulum. They play an essential role in lipid metabolism and cellular homeostasis.
Ana S. Martins +2 more
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Molecular Events Occurring in Lipophagy and Its Regulation in Flaviviridae Infection [PDF]
Frontiers in Microbiology, 2021 Diseases caused by Flaviviridae have a wide global and economic impact due to high morbidity and mortality. Flaviviridae infection usually leads to severe, acute or chronic diseases, such as liver injury and liver cancer resulting from hepatitis C virus (
Keke Wu +19 more
doaj +3 more sources
ICTV Virus Taxonomy Profile: Flaviviridae
Journal of General Virology, 2017 The Flaviviridae is a family of small enveloped viruses with RNA genomes of 9000–13 000 bases. Most infect mammals and birds. Many flaviviruses are host-specific and pathogenic, such as hepatitis C virus in the genus Hepacivirus.
Peter Simmonds +10 more
semanticscholar +4 more sources
PLoS Neglected Tropical Diseases, 2022 BackgroundViruses of the family Flaviviridae, including Japanese encephalitis virus (JEV), dengue virus (DENV), yellow fever virus (YFV) and hepatitis C virus (HCV), are widely distributed worldwide.
Ran Wang +6 more
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A New Subclass of Exoribonuclease-Resistant RNA Found in Multiple Genera of
mBio, 2020 Viruses have developed innovative strategies to exploit the cellular machinery and overcome the antiviral defenses of the host, often using specifically structured RNA elements.
Matthew J. Szucs +4 more
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Flaviviridae Nonstructural Proteins: The Role in Molecular Mechanisms of Triggering Inflammation
Viruses, 2022 Members of the Flaviviridae family are posing a significant threat to human health worldwide. Many flaviviruses are capable of inducing severe inflammation in humans.
Anastasia Latanova +2 more
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Dual-Role Ubiquitination Regulation Shuttling the Entire Life Cycle of the Flaviviridae
Frontiers in Microbiology, 2022 Ubiquitination is a reversible protein post-translational modification that regulates various pivotal physiological and pathological processes in all eukaryotes.
Dongjie Cai +12 more
doaj +2 more sources
Virus-host coevolution: common patterns of nucleotide motif usage in Flaviviridae and their hosts. [PDF]
PLoS ONE, 2009 Virus-host biological interaction is a continuous coevolutionary process involving both host immune system and viral escape mechanisms. Flaviviridae family is composed of fast evolving RNA viruses that infects vertebrate (mammals and birds) and/or ...
Francisco P Lobo +7 more
doaj +17 more sources
CRISPR–Cas system to discover host-virus interactions in Flaviviridae [PDF]
Virology Journal, 2023 The Flaviviridae virus family members cause severe human diseases and are responsible for considerable mortality and morbidity worldwide. Therefore, researchers have conducted genetic screens to enhance insight into viral dependency and develop potential
Zahra Ramezannia +2 more
doaj +2 more sources
Extracellular Vesicles in Flaviviridae Pathogenesis: Their Roles in Viral Transmission, Immune Evasion, and Inflammation. [PDF]
Int J Mol SciThe members of the Flaviviridae family are becoming an emerging threat for public health, causing an increasing number of infections each year and requiring effective treatment.
Latanova A, Karpov V, Starodubova E.
europepmc +2 more sources