Results 11 to 20 of about 827,603 (194)
Potential for Protein Kinase Pharmacological Regulation in Flaviviridae Infections. [PDF]
Int J Mol Sci, 2020 Protein kinases (PKs) are enzymes that catalyze the transfer of the terminal phosphate group from ATP to a protein acceptor, mainly to serine, threonine, and tyrosine residues. PK catalyzed phosphorylation is critical to the regulation of cellular signaling pathways that affect crucial cell processes, such as growth, differentiation, and metabolism ...
Blázquez AB, Saiz JC.
europepmc +6 more sources
Emerging Role of l-Dopa Decarboxylase in Flaviviridae Virus Infections [PDF]
Cells, 2019 l-dopa decarboxylase (DDC) that catalyzes the biosynthesis of bioactive amines, such as dopamine and serotonin, is expressed in the nervous system and peripheral tissues, including the liver, where its physiological role remains unknown.
Efseveia Frakolaki +8 more
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Perspectives for the Treatment of Infections with Flaviviridae [PDF]
Clinical Microbiology Reviews, 2000 SUMMARY The family Flaviviridae contains three genera: Hepacivirus, Flavivirus, and Pestivirus. Worldwide, more than 170 million people are chronically infected with Hepatitis C virus and are at risk of developing cirrhosis and/or liver cancer.
P, Leyssen, E, De Clercq, J, Neyts
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Innate Immune Evasion Mediated by Flaviviridae Non-Structural Proteins
Viruses, 2017 Flaviviridae-caused diseases are a critical, emerging public health problem worldwide. Flaviviridae infections usually cause severe, acute or chronic diseases, such as liver damage and liver cancer resulting from a hepatitis C virus (HCV) infection and ...
Shun Chen +3 more
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Live-Cell Imaging of Flaviviridae Family Virus Infections: Progress and Challenges
VirusesThe ability of a virus to be propagated within a host cell is dependent on a multitude of dynamic virus–host interactions. Live-cell imaging is an invaluable approach in the study of virus replication cycles and virus–host interactions as it can allow ...
Siena M. Centofanti, Nicholas S. Eyre
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Iminosugars: A host-targeted approach to combat Flaviviridae infections. [PDF]
Antiviral Res, 2020 N-linked glycosylation is the most common form of protein glycosylation and is required for the proper folding, trafficking, and/or receptor binding of some host and viral proteins. As viruses lack their own glycosylation machinery, they are dependent on the host's machinery for these processes.
Evans DeWald L +4 more
europepmc +3 more sources
Virology Journal, 2022 Background Zika virus (ZIKV), a member of the Flaviviridae family, has caused massive outbreaks of infection in tropical areas over the last decade and has now begun spreading to temperate countries.
Yannick Tréguier +7 more
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Anti-flavivirus Properties of Lipid-Lowering Drugs
Frontiers in Physiology, 2021 Although Flaviviruses such as dengue (DENV) and zika (ZIKV) virus are important human pathogens, an effective vaccine or antiviral treatment against them is not available. Hence, the search for new strategies to control flavivirus infections is essential.
Carlos Noe Farfan-Morales +8 more
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, 2022 The general sociodemographic characteristics of Flaviviridae virus infections during pediatric hospitalizations from December 2015 to December 2020.
Guoshuang Feng (4725078) +6 more
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Management of acute gingival bleeding in biphasic dengue fever with zinc oxide eugenol dressing
Indian Journal of Dental Sciences, 2023 Gingival bleeding is a common clinical finding associated with plague. It is also associated with systemic diseases, including viral and bacterial infections. Dengue hemorrhagic fever (DHF) is transmitted by virus belongs to Flaviviridae through infected
Gangadharan Vinodh +1 more
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