Iminosugars: A host-targeted approach to combat Flaviviridae infections. [PDF]
Antiviral Res, 2020 N-linked glycosylation is the most common form of protein glycosylation and is required for the proper folding, trafficking, and/or receptor binding of some host and viral proteins. As viruses lack their own glycosylation machinery, they are dependent on the host's machinery for these processes.
Evans DeWald L +4 more
europepmc +4 more sources
Bilateral optic neuritis as a complication of successive Flaviviridae virus infections [PDF]
Canadian Journal of Ophthalmology, 2020 Srinivasan Sanjay +2 more
exaly +4 more sources
N6 -Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection [PDF]
Cell Host and Microbe, 2016 The RNA modification N6-methyladenosine (m6A) post-transcriptionally regulates RNA function. The cellular machinery that controls m6A includes methyltransferases and demethylases that add or remove this modification, as well as m6A-binding YTHDF proteins that promote the translation or degradation of m6A-modified mRNA. We demonstrate that m6A modulates
Nandan S Gokhale +2 more
exaly +4 more sources
West Nile Virus: Seroprevalence and Epidemiological Study in Blood Donors in North Central Anatolia Amid Global Threats. [PDF]
J Med VirolABSTRACT West Nile virus (WNV) is a pathogen belonging to the family Flaviviridae and the genus Flavivirus. This study examined WNV IgG antibodies in healthy blood donors at Hitit University Blood Centre in Corum, Türkiye, during 2019–2020 using ELISA, thereby providing seroepidemiological data on WNV in northern central Anatolia.
Gureser AS +3 more
europepmc +2 more sources
Diagnostic challenges in Flaviviridae infections: first human case of Usutu virus aseptic meningitis in an immunocompetent subject in Italy [PDF]
International Journal of Infectious DiseasesObjectives: Usutu virus (USUV) is a mosquito-borne Orthoflavivirus. Human USUV infections are rare and are often asymptomatic or mild; however, neuroinvasive manifestations such as meningoencephalitis have occasionally been reported.
Giacomo Trillocco +8 more
doaj +2 more sources
Non-coding RNA: a key regulator of the pathogenicity and immunity of Flaviviridae viruses infection [PDF]
Cellular & Molecular Immunology, 2017 Non-coding RNA: a key regulator of the pathogenicity and immunity of Flaviviridae viruses ...
Zhiyi Zhang, Lifang Jiang, Gucheng Zeng
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Altered m 6 A modification of specific cellular transcripts affects Flaviviridae infection [PDF]
Molecular Cell, 2019 Summary The RNA modification N6 -methyladenosine (m 6 A) can modulate mRNA fate and thus affect many biological processes. We analyzed m 6 A modification across the transcriptome following infection by dengue ...
Nandan S. Gokhale +6 more
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Perspectives for the Treatment of Infections with Flaviviridae [PDF]
Clinical Microbiology Reviews, 2000 SUMMARYThe family Flaviviridae contains three genera: Hepacivirus, Flavivirus, and Pestivirus. Worldwide, more than 170 million people are chronically infected with Hepatitis C virus and are at risk of developing cirrhosis and/or liver cancer. In addition, infections with arthropod-borne flaviviruses (such as dengue fever, Japanese encephalitis, tick ...
Pieter Leyssen +2 more
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Infection, Dissemination, and Replication of Urban and Sylvatic Strains of Dengue Virus Type 2 (Flaviviridae: Flavivirus) in Australian Aedes aegypti (Diptera: Culicidae) [PDF]
Journal of Medical Entomology, 2021 Abstract The dengue viruses (DENVs) occur throughout tropical and subtropical regions of the world where they infect 100s of millions of people annually. In Australia, the dengue receptive zone is confined to the northern state of Queensland where the principal vector Aedes aegypti (L.) is present.
Sonja Hall‐Mendelin +7 more
openalex +5 more sources
Bilateral optic neuritis as a complication of successive Flaviviridae virus infections [PDF]
Canadian Journal of Ophthalmology, 2019 Julius Vladimir Ilin +4 more
openalex +2 more sources