Results 21 to 30 of about 26,859 (204)

Perspectives for the Treatment of Infections with Flaviviridae

Clinical Microbiology Reviews, 2000
Pieter Leyssen, Erik De Clercq, Johan Neyts   +2 more
exaly   +2 more sources

Virus discovery reveals frequent infection by diverse novel members of the Flaviviridae in wild lemurs [PDF]

Archives of Virology, 2018
Lemurs are highly endangered mammals inhabiting the forests of Madagascar. In this study, we performed virus discovery on serum samples collected from 84 wild lemurs and identified viral sequence fragments from 4 novel viruses within the family Flaviviridae, including members of the genera Hepacivirus and Pegivirus.
Marta Canuti, Cathy V. Williams, Selena M. Sagan, Bas B. Oude Munnink, Sashi Gadi, Joost T. P. Verhoeven, Paul Kellam, Matthew Cotten, Andrew S. Lang, Randall E. Junge, John M. Cullen, Lia van der Hoek   +11 more
openalex   +5 more sources

Examining innate responses to Flaviviridae infection: how myeloid cells respond to and are modulated by bovine viral diarrhea virus in vivo and in vitro.

, 2012
Disease associated with BVDV infection can be devastating ranging to millions of dollars in loss to the cattle industry. As well, infection with BVDV leads to an immune-suppressed host though an unknown mechanism(s). Although there are vaccines available, they are not broadly protective and ineffective in PI cattle.
Robert G. Schaut
openalex   +4 more sources

Zika virus serological diagnosis: commercial tests and monoclonal antibodies as tools [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2020
Zika virus (ZIKV), an emerging arthropod-borne virus (arbovirus) of the Flaviviridae family, is a current issue worldwide, particularly because of the congenital and neurological syndromes associated with infection by this virus.
Isaura Beatriz Borges Silva, Aldacilene Souza da Silva, Mariana Sequetin Cunha, Aline Diniz Cabral, Kelly Cristina Alves de Oliveira, Elizabeth De Gaspari, Carlos Roberto Prudencio   +6 more
doaj   +1 more source

Identification of novel neutralizing determinants for protection against HCV

Hepatology, EarlyView., 2022
Identification of novel neutralizing determinants for protection against hepatitis C virus. Abstract Background and Aims HCV evasion of neutralizing antibodies (nAb) results in viral persistence and poses challenges to the development of an urgently needed vaccine.
Garazi P. Alzua, Anne F. Pihl, Anna Offersgaard, Rodrigo Velázquez‐Moctezuma, Carlos R. Duarte Hernandez, Elias H. Augestad, Ulrik Fahnøe, Christian K. Mathiesen, Henrik Krarup, Mansun Law, Jannick Prentoe, Jens Bukh, Judith M. Gottwein   +12 more
wiley   +1 more source

Encephalitic Arboviruses of Africa: Emergence, Clinical Presentation and Neuropathogenesis

Frontiers in Immunology, 2021
Many mosquito-borne viruses (arboviruses) are endemic in Africa, contributing to systemic and neurological infections in various geographical locations on the continent. While most arboviral infections do not lead to neuroinvasive diseases of the central
Robyn S. Klein
doaj   +1 more source

The envelope protein of Zika virus interacts with apolipoprotein E early in the infectious cycle and this interaction is conserved on the secreted viral particles

Virology Journal, 2022
Background Zika virus (ZIKV), a member of the Flaviviridae family, has caused massive outbreaks of infection in tropical areas over the last decade and has now begun spreading to temperate countries.
Yannick Tréguier, Jade Cochard, Julien Burlaud-Gaillard, Roxane Lemoine, Philippe Chouteau, Philippe Roingeard, Jean-Christophe Meunier, Marianne Maquart   +7 more
doaj   +1 more source

Pathogenesis of Modoc Virus (Flaviviridae; Flavivirus) in Persistently Infected Hamsters [PDF]

The American Society of Tropical Medicine and Hygiene, 2013
The long-term persistence of Modoc virus (MODV) infection was investigated in a hamster model. Golden hamsters (Mesocricetus auratus) were infected by subcutaneous inoculation with MODV, in which fatal encephalitis developed in 12.5% (2 of 16). Surviving hamsters shed infectious MODV in their urine during the first five months after infection, and ...
A Paige, Adams, Amelia P A, Travassos da Rosa, Marcio R, Nunes, Shu-Yuan, Xiao, Robert B, Tesh   +4 more
openaire   +2 more sources

Anti-flavivirus Properties of Lipid-Lowering Drugs

Frontiers in Physiology, 2021
Although Flaviviruses such as dengue (DENV) and zika (ZIKV) virus are important human pathogens, an effective vaccine or antiviral treatment against them is not available. Hence, the search for new strategies to control flavivirus infections is essential.
Carlos Noe Farfan-Morales, Carlos Daniel Cordero-Rivera, José Manuel Reyes-Ruiz, Arianna M. Hurtado-Monzón, Juan Fidel Osuna-Ramos, Arely M. González-González, Luis Adrián De Jesús-González, Selvin Noé Palacios-Rápalo, Rosa María del Ángel   +8 more
doaj   +1 more source

Management of acute gingival bleeding in biphasic dengue fever with zinc oxide eugenol dressing

Indian Journal of Dental Sciences, 2023
Gingival bleeding is a common clinical finding associated with plague. It is also associated with systemic diseases, including viral and bacterial infections. Dengue hemorrhagic fever (DHF) is transmitted by virus belongs to Flaviviridae through infected
Gangadharan Vinodh, Manonmani Balasubramanian   +1 more
doaj   +1 more source