Results 21 to 30 of about 18,525 (157)

Potential for Protein Kinase Pharmacological Regulation in Flaviviridae Infections. [PDF]

Int J Mol Sci, 2020
Protein kinases (PKs) are enzymes that catalyze the transfer of the terminal phosphate group from ATP to a protein acceptor, mainly to serine, threonine, and tyrosine residues.
Blázquez AB, Saiz JC.
europepmc   +3 more sources

A Review on The Pathogenesis of Cardiovascular Disease of Flaviviridea Viruses Infection

Viruses
Members of the Flaviviridae family, encompassing the Flavivirus and Hepacivirus genera, are implicated in a spectrum of severe human pathologies. These diseases span a diverse spectrum, including hepatitis, vascular shock syndrome, encephalitis, acute ...
Tie-Hua Yang, Wen-Cong Gao, Xin Ma, Qian Liu, Pan-Pan Pang, Yong-Tang Zheng, Yinnong Jia, Chang-Bo Zheng   +7 more
doaj   +2 more sources

Serological Diagnosis of Flavivirus-Associated Human Infections

Diagnostics, 2020
Arthropod-borne viruses (arboviruses) belonging to the Flavivirus genus of the Flaviviridae family, are a major public health threat in tropical and subtropical regions, and have recently become a medical concern in temperate zones. Most flaviviruses are
Didier Musso, Philippe Desprès
doaj   +2 more sources

Protein-driven membrane remodeling: Molecular perspectives from Flaviviridae infections [PDF]

Biophysical Journal, 2023
Viviana Monje-Galvan
exaly   +2 more sources

Cyclophilins and Their Roles in Hepatitis C Virus and Flavivirus Infections: Perspectives for Novel Antiviral Approaches

Pathogens, 2021
Cyclophilins are cellular peptidyl-prolyl isomerases that play an important role in viral infections, with demonstrated roles in the replication of hepatitis C virus (HCV) and other viruses in the Flaviviridae family, such as dengue virus (DENV) and ...
Carla E. Gallardo-Flores, Che C. Colpitts   +1 more
doaj   +2 more sources

Zika virus serological diagnosis: commercial tests and monoclonal antibodies as tools [PDF]

Journal of Venomous Animals and Toxins including Tropical Diseases, 2020
Zika virus (ZIKV), an emerging arthropod-borne virus (arbovirus) of the Flaviviridae family, is a current issue worldwide, particularly because of the congenital and neurological syndromes associated with infection by this virus.
Isaura Beatriz Borges Silva, Aldacilene Souza da Silva, Mariana Sequetin Cunha, Aline Diniz Cabral, Kelly Cristina Alves de Oliveira, Elizabeth De Gaspari, Carlos Roberto Prudencio   +6 more
doaj   +1 more source

Encephalitic Arboviruses of Africa: Emergence, Clinical Presentation and Neuropathogenesis

Frontiers in Immunology, 2021
Many mosquito-borne viruses (arboviruses) are endemic in Africa, contributing to systemic and neurological infections in various geographical locations on the continent. While most arboviral infections do not lead to neuroinvasive diseases of the central
Robyn S. Klein
doaj   +1 more source

Identification of novel neutralizing determinants for protection against HCV

Hepatology, EarlyView., 2022
Identification of novel neutralizing determinants for protection against hepatitis C virus. Abstract Background and Aims HCV evasion of neutralizing antibodies (nAb) results in viral persistence and poses challenges to the development of an urgently needed vaccine.
Garazi P. Alzua, Anne F. Pihl, Anna Offersgaard, Rodrigo Velázquez‐Moctezuma, Carlos R. Duarte Hernandez, Elias H. Augestad, Ulrik Fahnøe, Christian K. Mathiesen, Henrik Krarup, Mansun Law, Jannick Prentoe, Jens Bukh, Judith M. Gottwein   +12 more
wiley   +1 more source

The envelope protein of Zika virus interacts with apolipoprotein E early in the infectious cycle and this interaction is conserved on the secreted viral particles

Virology Journal, 2022
Background Zika virus (ZIKV), a member of the Flaviviridae family, has caused massive outbreaks of infection in tropical areas over the last decade and has now begun spreading to temperate countries.
Yannick Tréguier, Jade Cochard, Julien Burlaud-Gaillard, Roxane Lemoine, Philippe Chouteau, Philippe Roingeard, Jean-Christophe Meunier, Marianne Maquart   +7 more
doaj   +1 more source

Anti-flavivirus Properties of Lipid-Lowering Drugs

Frontiers in Physiology, 2021
Although Flaviviruses such as dengue (DENV) and zika (ZIKV) virus are important human pathogens, an effective vaccine or antiviral treatment against them is not available. Hence, the search for new strategies to control flavivirus infections is essential.
Carlos Noe Farfan-Morales, Carlos Daniel Cordero-Rivera, José Manuel Reyes-Ruiz, Arianna M. Hurtado-Monzón, Juan Fidel Osuna-Ramos, Arely M. González-González, Luis Adrián De Jesús-González, Selvin Noé Palacios-Rápalo, Rosa María del Ángel   +8 more
doaj   +1 more source