Ocular Manifestations of Flavivirus Infections [PDF]
Pathogens, 2023 Flaviviruses are a group of positive-sense, single-stranded RNA viruses predominantly transmitted by arthropods (mainly mosquitoes) that cause severe endemic infections and epidemics on a global scale.
Sourour Meziou Zina +4 more
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Pathogenesis and virulence of flavivirus infections [PDF]
Virulence, 2021 The Flavivirus genus consists of >70 members including several that are considered significant human pathogens. Flaviviruses display a broad spectrum of diseases that can be roughly categorised into two phenotypes – systemic disease involving haemorrhage
Sophie Wilhelmina van Leur +3 more
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TRIMming down Flavivirus Infections [PDF]
VirusesFlaviviruses comprise a large number of arthropod-borne viruses, some of which are associated with life-threatening diseases. Flavivirus infections are rising worldwide, mainly due to the proliferation and geographical expansion of their vectors.
Marion Cannac, Sébastien Nisole
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The role of γδ T cells in flavivirus infections: Insights into immune defense and therapeutic opportunities. [PDF]
PLoS Neglected Tropical Diseasesγδ T cells are a unique subset of unconventional T cells and an important component of the innate immune system. Unlike conventional αβ T cells, γδ T cells can respond rapidly during the early stages of infection, and their antigen recognition is not ...
Qi Li +7 more
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The global incidence and trends of three common flavivirus infections (Dengue, yellow fever, and Zika) from 2011 to 2021 [PDF]
Frontiers in MicrobiologyBackgroundFlavivirus pose a continued threat to global health, yet their worldwide burden and trends remain poorly quantified. We aimed to evaluate the global, regional, and national incidence of three common flavivirus infections (Dengue, yellow fever ...
Yuanhao Liang, Xingzhu Dai
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Oral Antibiotic Treatment of Mice Exacerbates the Disease Severity of Multiple Flavivirus Infections [PDF]
Cell Reports, 2018 Summary: Although the outcome of flavivirus infection can vary from asymptomatic to lethal, environmental factors modulating disease severity are poorly defined.
Larissa B. Thackray +15 more
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Structures and Functions of the Envelope Glycoprotein in Flavivirus Infections [PDF]
Viruses, 2017 Flaviviruses are enveloped, single-stranded RNA viruses that widely infect many animal species. The envelope protein, a structural protein of flavivirus, plays an important role in host cell viral infections.
Xingcui Zhang +5 more
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Cellular Targets for the Treatment of Flavivirus Infections [PDF]
Frontiers in Cellular and Infection Microbiology, 2018 Classical antiviral therapy targets viral functions, mostly viral enzymes or receptors. Successful examples include precursor herpesvirus drugs, antiretroviral drugs that target reverse transcriptase and protease, influenza virus directed compounds as ...
Mohammad Khalid Zakaria +2 more
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Resveratrol as an epigenetic therapy for flavivirus infection: A narrative review
Asian Pacific Journal of Tropical Medicine, 2023 Flaviviruses are a group of positive-stranded RNA viruses that cause a broad spectrum of severe illnesses in humans worldwide. Clinical manifestations of flavivirus infections range from mild febrile illness to hemorrhage, shock, and neurological ...
Kim-Ling Chin +3 more
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Flavivirus: From Structure to Therapeutics Development
Life, 2021 Flaviviruses are still a hidden threat to global human safety, as we are reminded by recent reports of dengue virus infections in Singapore and African-lineage-like Zika virus infections in Brazil.
Rong Zhao +6 more
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