Results 21 to 30 of about 28,583 (169)
Veterinary Research, 2021 Flaviviruses are enveloped single positive-stranded RNA viruses. The capsid (C), a structural protein of flavivirus, is dimeric and alpha-helical, with several special structural and functional features.
Xingcui Zhang +5 more
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TRIMming Flavivirus Infection [PDF]
Cell Host & Microbe, 2011 Tripartite motif (TRIM) proteins are novel players in antiviral innate immunity. In this issue of Cell Host & Microbe,Taylor et al. (2011) discover the mechanism of action of TRIM79α and show that this interferon-induced protein restricts tick-borne flaviviruses by targeting the viral polymerase for degradation.
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Regulation of Apoptosis during Flavivirus Infection [PDF]
Viruses, 2017 Apoptosis is a type of programmed cell death that regulates cellular homeostasis by removing damaged or unnecessary cells. Its importance in host defenses is highlighted by the observation that many viruses evade, obstruct, or subvert apoptosis, thereby blunting the host immune response.
Toru Okamoto +6 more
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Microbiology Spectrum, 2023 The flavivirus non-structural protein 1 (NS1) is secreted from infected cells into the circulation and the serum levels correlate with disease severity. The effect of secreted NS1 (sNS1) on non-infected mammalian immune cells is largely unknown. Here, we
António A. R. Camarão +9 more
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Oculopathologic Findings in Flavivirus-Infected Gallinaceous Birds [PDF]
Veterinary Pathology, 2014 Using eye samples of nine 9-week-old experimentally West Nile virus (WNV)–infected red-legged partridges ( Alectoris rufa), time course of lesions and WNV antigen appearance in ocular structures were examined. In addition, eye samples of 6 red-legged partridges and 3 common pheasants ( Phasianus colchicus) naturally infected with Bagaza virus (BAGV ...
Gamino, V. +5 more
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Neutrophil Recruitment and Participation in Severe Diseases Caused by Flavivirus Infection
Life, 2021 Neutrophils are first-line responders to infections and are recruited to target tissues through the action of chemoattractant molecules, such as chemokines. Neutrophils are crucial for the control of bacterial and fungal infections, but their role in the
Marina Alves Fontoura +2 more
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Host genetic control of mosquito-borne Flavivirus infections. [PDF]
Mamm Genome, 2018 Flaviviruses are arthropod-borne viruses, several of which represent emerging or re-emerging pathogens responsible for widespread infections with consequences ranging from asymptomatic seroconversion to severe clinical diseases and congenital developmental deficits.
Manet C +5 more
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Are we prepared for emerging flaviviruses in Europe? Challenges for vaccination
Human Vaccines & Immunotherapeutics, 2018 Tick-borne encephalitis and West Nile fever are endemic flavivirus diseases in Europe. Climate change, virus evolution, and social factors may increase the risk of these flavivirus infections and may lead to the emergence of other flaviviruses in Europe ...
Patricia Kaaijk, Willem Luytjes
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Infection order outweighs the role of CD4+ T cells in tertiary flavivirus exposure
iScience, 2022 Summary: The link between CD4+ T and B cells during immune responses to DENV and ZIKV and their roles in cross-protection during heterologous infection is an active area of research.
Nicole Marzan-Rivera +13 more
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Macrophage immunometabolism during flavivirus infection
, 2022 Dengue virus (DENV) and Zika virus (ZIKV) are mosquito borne flaviviruses that are transmitted by the Aedes spp. mosquito and have caused outbreaks in Africa, Asia, the south Pacific, and the Americas. Infection with DENV can cause severe illness, such as dengue hemorrhagic fever and dengue shock syndrome, while infection with ZIKV can result in ...
Donkoh, Jasmine, author +5 more
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