Results 71 to 80 of about 28,583 (169)
Human Cyclophilins—An Emerging Class of Drug Targets
Medicinal Research Reviews, Volume 46, Issue 2, Page 475-512, March 2026.ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
wiley +1 more source
Langat Virus Biology and Infection
Reviews in Medical Virology, Volume 36, Issue 2, March 2026.ABSTRACT Flaviviruses pose a major threat to global health and can cause severe disease in animals and humans. Among them, tick‐borne encephalitis virus (TBEV) and related members of the tick‐borne encephalitis (TBE) serocomplex are transmitted primarily by ticks and can lead to neurological disease, including encephalitis and death. Despite many years
Zinaida Klestova +3 more
wiley +1 more source
Small, Volume 22, Issue 14, 6 March 2026.A novel, non‐destructive, stable, direct technique, named correlated plasmon‐enhanced Raman spectroscopy (CP‐ERS), which is based on a newly‐developed highly oriented single crystalline gold quantum dots (HOSG‐QDs) chip, is developed to measure and quantify molecular vibrations and electronic structure of analytes.
Vashu Kamboj +7 more
wiley +1 more source
The Role of Companion Animals as ‘Sentinels’ From the One Health Perspective
Veterinary Medicine and Science, Volume 12, Issue 2, March 2026.One Health emphasizes the interconnection of human, animal and environmental health. As emotional extensions of humans, companion dogs and cats can serve as sentinels, detecting hazards that can help protect human health from the One Health perspective. When symptoms appear in pets, owners should notice the changes that may pose risks to both human and
Shenchen Kang, Yu Chen, Mengmeng Liu
wiley +1 more source
The Immunopathogenesis of Neurotropic Flavivirus Infection [PDF]
, 2011 The flavivirus genus in the Flaviviridae family comprises over 70 species, most of which are tickor mosquito-borne. They are single-stranded, plus-sense RNA viruses, responsible for significant human and animal morbidity and mortality on all inhabited continents.
NJC, King +8 more
openaire +2 more sources
NAD+ Homeostasis Attenuates Japanese Encephalitis Virus Infection Progression
The FASEB Journal, Volume 40, Issue 4, 28 February 2026.JEV infection in brain tissue triggers inflammation and stress in neuronal cells, leading to NAD+ depletion via the overactivation of PARPs and SIRTs. While compensatory biosynthetic pathways (de novo and salvage) were upregulated, the NAD+ level fell critically. In vitro NAMPT inhibition exacerbates this deficit and viral load.
Takele Adugna Kassegn +10 more
wiley +1 more source
Viruses, 2020 The arthropod-borne flaviviruses are important human pathogens, and a deeper understanding of the virus–host cell interaction is required to identify cellular targets that can be used as therapeutic candidates.
José Manuel Reyes-Ruiz +10 more
doaj +1 more source
DEVELOPMENT OF A MODEL FOR SURVEILLANCE AND CONTROL OF FLAVIVIRUSES IN HUMAN POPULATION
Archives of Veterinary Medicine, 2015 The aim of this study is development of a model for monitoring and control of vector-transmitted diseases, which manifest increasing tendency during the last few decades.
Vesna Milošević +6 more
doaj +1 more source
Claudin-derived peptides inhibit Flavivirus infections
, 2022 No abstract ...
Zoladek, Jim, Afonso, Philippe V.
openaire +1 more source
Role of pattern recognition receptors in flavivirus infections
Virus Research, 2014 The flaviviral encephalitis has now become a major health concern in global scale. The efficient detection of viral infection and induction of the innate antiviral response by host's innate immune system are crucial to determine the outcome of infection.
Arshed, Nazmi +3 more
openaire +2 more sources