Results 1 to 10 of about 26,788 (261)

Chimeric Vaccines Based on Novel Insect-Specific Flaviviruses

open access: yesVaccines, 2021
Vector-borne flaviviruses are responsible for nearly half a billion human infections worldwide each year, resulting in millions of cases of debilitating and severe diseases and approximately 115,000 deaths.
J. Harrison   +3 more
semanticscholar   +1 more source

Lack of Durable Cross-Neutralizing Antibodies Against Zika Virus from Dengue Virus Infection

open access: yesEmerging Infectious Diseases, 2017
Cross-reactive antibodies elicited by dengue virus (DENV) infection might affect Zika virus infection and confound serologic tests. Recent data demonstrate neutralization of Zika virus by monoclonal antibodies or human serum collected early after DENV ...
Matthew H. Collins   +7 more
doaj   +1 more source

Development of genus-specific universal primers for the detection of flaviviruses

open access: yesVirology Journal, 2021
Background Flaviviruses are representative arboviruses carried by arthropods and/or vertebrates; these viruses can pose a public health concern in many countries. By contrast, it is known that a novel virus group called insect-specific flaviviruses (ISFs)
Tomo Daidoji   +9 more
doaj   +1 more source

Innate Immune Antagonism of Mosquito-Borne Flaviviruses in Humans and Mosquitoes

open access: yesViruses, 2021
Mosquito-borne viruses of the Flavivirus genus (Flaviviridae family) pose an ongoing threat to global public health. For example, dengue, Japanese encephalitis, West Nile, yellow fever, and Zika viruses are transmitted by infected mosquitoes and cause ...
A. Elrefaey   +4 more
semanticscholar   +1 more source

Emerging mosquito-borne flaviviruses

open access: yesmBio
Flaviviruses comprise a genus of enveloped, positive-sense, single-stranded RNA viruses typically transmitted between susceptible and permissive hosts by arthropod vectors. Established flavivirus threats include dengue viruses (DENV), yellow fever virus (
Amy N. Nelson, A. Ploss
semanticscholar   +1 more source

Detection of Insect-Specific Flaviviruses in Mosquitoes (Diptera: Culicidae) in Northeastern Regions of South Africa

open access: yesViruses, 2021
Mosquitoes in the Aedes and Culex genera are considered the main vectors of pathogenic flaviviruses worldwide. Entomological surveillance using universal flavivirus sets of primers in mosquitoes can detect not only pathogenic viruses but also insect ...
M. Guarido   +7 more
semanticscholar   +1 more source

Anti-flavi: A Web Platform to Predict Inhibitors of Flaviviruses Using QSAR and Peptidomimetic Approaches

open access: yesFrontiers in Microbiology, 2018
Flaviviruses are arboviruses, which comprises more than 70 viruses, covering broad geographic ranges, and responsible for significant mortality and morbidity globally. Due to the lack of efficient inhibitors targeting flaviviruses, the designing of novel
Akanksha Rajput, Manoj Kumar
doaj   +1 more source

Flavivirus cross-reactivity: Insights into e-protein conservancy, pre-existing immunity, and co-infection

open access: yesThe Microbe
Flaviviruses are enveloped, single-stranded RNA viruses that are largely arthropod-borne, circulating globally and infecting up to 400 million people annually.
Abdulbariu Ogirima Uhuami   +3 more
doaj   +1 more source

Flaviviruses of public health concern in South Africa: Present and future threats

open access: yesSouthern African Journal of Infectious Diseases
Background: The resurgence and widespread transmission of flaviviruses over the past few decades are particularly concerning. Aim: This review discusses the structure, aetiology, transmission, detection, diagnosis and prevention strategies for ...
Angela Sibanda-Makuvise   +2 more
doaj   +1 more source

Viral and Prion Infections Associated with Central Nervous System Syndromes in Brazil

open access: yesViruses, 2021
Virus-induced infections of the central nervous system (CNS) are among the most serious problems in public health and can be associated with high rates of morbidity and mortality, mainly in low- and middle-income countries, where these manifestations ...
Ivanildo P. Sousa   +6 more
doaj   +1 more source

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