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Mosquito-Borne Flaviviruses and Current Therapeutic Advances [PDF]

open access: goldViruses, 2022
Mosquito-borne flavivirus infections affect approximately 400 million people worldwide each year and are global threats to public health. The common diseases caused by such flaviviruses include West Nile, yellow fever, dengue, Zika infection and Japanese
X. Qian, Zhongtian Qi
semanticscholar   +2 more sources

Flaviviruses as agents of childhood central nervous system infections in Brazil

open access: goldNew Microbes and New Infections, 2019
Flaviviruses are agents of a major emerging human public health issue, and members of the Flavivirus genus have been associated with central nervous system (CNS) infections.
P.E. Silva Marinho, E.G. Kroon
doaj   +4 more sources

Flaviviruses: Innate Immunity, Inflammasome Activation, Inflammatory Cell Death, and Cytokines

open access: yesFrontiers in Immunology, 2022
The innate immune system is the host’s first line of defense against the invasion of pathogens including flavivirus. The programmed cell death controlled by genes plays an irreplaceable role in resisting pathogen invasion and preventing pathogen ...
Yuhong Pan   +15 more
doaj   +2 more sources

Arthropod-Borne Flaviviruses in Pregnancy [PDF]

open access: goldMicroorganisms, 2023
Flaviviruses are a diverse group of enveloped RNA viruses that cause significant clinical manifestations in the pregnancy and postpartum periods. This review highlights the epidemiology, pathophysiology, clinical features, diagnosis, and prevention of ...
A. Howard-Jones   +6 more
semanticscholar   +2 more sources

Widespread Circulation of Flaviviruses in Horses and Birds in Northeastern Spain (Catalonia) between 2010 and 2019

open access: yesViruses, 2021
The surveillance for West Nile virus (WNV) in Catalonia (northeastern Spain) has consistently detected flaviviruses not identified as WNV. With the aim of characterizing the flaviviruses circulating in Catalonia, serum samples from birds and horses ...
Sebastian Napp   +14 more
doaj   +2 more sources

Finding a chink in the armor: Update, limitations, and challenges toward successful antivirals against flaviviruses

open access: goldPLoS Neglected Tropical Diseases, 2022
Flaviviruses have caused large epidemics and ongoing outbreaks for centuries. They are now distributed in every continent infecting up to millions of people annually and may emerge to cause future epidemics.
Thamil Vaani Komarasamy   +3 more
semanticscholar   +3 more sources

Secretory glycoprotein NS1 plays a crucial role in the particle formation of flaviviruses.

open access: yesPLoS Pathogens, 2022
Flaviviruses, which are globally distributed and cause a spectrum of potentially severe illnesses, pose a major threat to public health. Although Flaviviridae viruses, including flaviviruses, possess similar genome structures, only the flaviviruses ...
Tomokazu Tamura   +14 more
doaj   +2 more sources

Emerging mosquito-borne flaviviruses

open access: goldmBio
Flaviviruses comprise a genus of enveloped, positive-sense, single-stranded RNA viruses typically transmitted between susceptible and permissive hosts by arthropod vectors. Established flavivirus threats include dengue viruses (DENV), yellow fever virus (
Amy N. Nelson, A. Ploss
semanticscholar   +2 more sources

Magnitude of Antibody Cross-Reactivity in Medically Important Mosquito-Borne Flaviviruses: A Systematic Review

open access: yesInfection and Drug Resistance, 2021
Adugna Endale,1,2 Girmay Medhin,1 Koyamo Darfiro,3 Nigatu Kebede,1 Mengistu Legesse1 1Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa, Ethiopia; 2School of Medicine, College of Medicine and Health Sciences, Dire Dawa ...
Endale A   +4 more
doaj   +2 more sources

Lipid Interactions Between Flaviviruses and Mosquito Vectors

open access: yesFrontiers in Physiology, 2021
Mosquito-borne flaviviruses, such as dengue (DENV), Zika (ZIKV), yellow fever (YFV), West Nile (WNV), and Japanese encephalitis (JEV) viruses, threaten a large part of the human populations.
Thomas Vial   +5 more
doaj   +2 more sources

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