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Flaviviruses are positive-sense single-stranded RNA viruses, including some well-known human pathogens such as Zika, dengue, and yellow fever viruses, which are primarily associated with mosquito and tick vectors. The vast majority of flavivirus research
Megan J. Lensink +2 more
semanticscholar +5 more sources
Acute neurologic emerging flaviviruses
The COVID-19 pandemic has shed light on the challenges we face as a global society in preventing and containing emerging and re-emerging pathogens. Multiple intersecting factors, including environmental changes, host immunological factors, and pathogen ...
Marissa Caldwell, A. Boruah, K. Thakur
semanticscholar +4 more sources
mRNA Vaccines against Flaviviruses [PDF]
Numerous vaccines have now been developed using the mRNA platform. In this approach, mRNA coding for a viral antigen is in vitro synthesized and injected into the host leading to exogenous protein expression and robust immune responses.
Clayton J Wollner, Justin M. Richner
semanticscholar +4 more sources
Biosensors for the detection of flaviviruses: A review
Flaviviruses affect the lives of millions of people in endemic regions and also have the potential to impact non-endemic areas. Factors such as climate change, global warming, deforestation, and increased travel and trade are linked to the spread of ...
Ana-Belén Blázquez +1 more
doaj +2 more sources
Structural elucidation of Langat virus helicase unveils dual-target inhibition for broad-spectrum anti-flaviviruses strategy. [PDF]
Li R, Han Z, He X, Zhong R, Chen C.
europepmc +3 more sources
Yellow fever virus (YFV) caused an outbreak in the Brazilian Southeast from 2016 to 2019, of the most significant magnitude since the 1900s. An investigation of the circulating virus revealed that most of the genomes detected in this period carried nine ...
Nathália Dias Furtado +4 more
doaj +1 more source
Serological cross-reactivity among common flaviviruses
The Flavivirus genus is made up of viruses that are either mosquito-borne or tick-borne and other viruses transmitted by unknown vectors. Flaviviruses present a significant threat to global health and infect up to 400 million of people annually.
Kai Rol Chan +6 more
semanticscholar +1 more source
Mechanisms of Neuroinvasion and Neuropathogenesis by Pathologic Flaviviruses
Flaviviruses are present on every continent and cause significant morbidity and mortality. In many instances, severe cases of infection with flaviviruses involve the invasion of and damage to the central nervous system (CNS). Currently, there are several
Liset de Vries, Alfred T. Harding
semanticscholar +1 more source
Horses as Sentinels for the Circulation of Flaviviruses in Eastern–Central Germany
Since 2018, autochthonous West Nile virus (WNV) infections have been regularly reported in eastern–central Germany. While clinically apparent infections in humans and horses are not frequent, seroprevalence studies in horses may allow the tracing of WNV ...
Leonard M R Gothe +9 more
semanticscholar +1 more source

