Results 61 to 70 of about 26,788 (261)
Frontiers in Microbiology, 2019 Human infection by different flaviviruses may cause severe neurologic syndromes, through pathogenic mechanisms that are still largely unknown. Japanese encephalitis virus (JEV), West Nile virus (WNV), Zika virus (ZIKV), yellow fever virus (YFV), dengue ...
Y. M. Mustafá +3 more
semanticscholar +1 more source
Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents
Advanced Functional Materials, EarlyView.Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras +6 more
wiley +1 more source
Frontiers in Cellular and Infection Microbiology, 2021 West Nile virus (WNV) causes West Nile fever and encephalitis worldwide. Currently, there are no effective drugs or vaccines available in the market to treat WNV infection in humans.
Priyanka Singh Tomar +3 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.This review summarizes the main uptake pathways of bioactive glass nanoparticles (BGNs) and their intracellular localization, highlighting that BGNs are mainly internalized and entrapped within endosomes/lysosomes. Strategies for controlled intracellular ion release, with implications for targeted modulation of cell behavior, are discussed. The need to
Andrada‐Ioana Damian‐Buda +1 more
wiley +1 more source
Lyn kinase regulates egress of flaviviruses in autophagosome-derived organelles
Nature Communications, 2020 Among the various host cellular processes that are hijacked by flaviviruses, few mechanisms have been described with regard to viral egress. Here we investigate how flaviviruses exploit Src family kinases (SFKs) for exit from infected cells.
Ming Yuan Li +11 more
semanticscholar +1 more source
Carbon Quantum Dots Assisted Virus Tracking: From Skin to Brain
Advanced Materials, EarlyView.A novel carbon quantum dots‐dissolvable microneedle, CQDs‐dMN system, enables painless delivery and real‐time tracking of HSV‐1. The HSV‐1 is labeled with fluorescent CQDs and delivered to the skin dermis, minimizing damage compared to traditional methods.
Yaxiu Feng +11 more
wiley +1 more source
Advanced Science, EarlyView.A simple and general photoactivatable approach is developed to regulate DNA polymerase activity, enabling light‐start isothermal amplification on demand. The molecular dynamics simulations reveals that the photocaged primer blocks DNA polymerase activity by inhibiting the conformational change of the polymerase.
Min Qing +7 more
wiley +1 more source
Continuous surveillance of potentially zoonotic avian pathogens detects contemporaneous occurrence of highly pathogenic avian influenza viruses (HPAIV H5) and flaviviruses (USUV, WNV) in several wild and captive birds [PDF]
, 2023 Anne Günther +10 more
openalex +1 more source
A CRISPR screen defines a signal peptide processing pathway required by flaviviruses
Nature, 2016 Flaviviruses infect hundreds of millions of people annually, and no antiviral therapy is available. We performed a genome-wide CRISPR/Cas9-based screen to identify host genes that, when edited, resulted in reduced flavivirus infection. Here, we validated
Rong Zhang +13 more
semanticscholar +1 more source
Insect I‐Type Lysozymes Function as Antiviral Proteases by Forming Biomolecular Condensates
Advanced Science, EarlyView.Upon rice viral infection, the insect vector activates the Toll–MyD88–Dorsal signaling cascade, inducing i‐type lysozyme (Lyz‐I1) expression. Lyz‐I1 functions as an antiviral protease through its conserved catalytic dyad Glu/Asp (E/D), mediating cleavage of viral proteins at specific Lys (K) residues.
Yu Du +5 more
wiley +1 more source