Results 71 to 80 of about 40,077 (289)
Lyn kinase regulates egress of flaviviruses in autophagosome-derived organelles
Among the various host cellular processes that are hijacked by flaviviruses, few mechanisms have been described with regard to viral egress. Here we investigate how flaviviruses exploit Src family kinases (SFKs) for exit from infected cells.
Ming Yuan Li +11 more
semanticscholar +1 more source
Inhibition of type I interferon induction and signalling by mosquito-borne flaviviruses [PDF]
The Flavivirus genus (Flaviviridae family) contains a number of important human pathogens, including dengue and Zika viruses, which have the potential to cause severe disease.
Clark, Jordan J. +3 more
core +1 more source
Mosquitoes in the Aedes and Culex genera are considered the main vectors of pathogenic flaviviruses worldwide. Entomological surveillance using universal flavivirus sets of primers in mosquitoes can detect not only pathogenic viruses but also insect ...
M. Guarido +7 more
semanticscholar +1 more source
Virucidal Approaches for Hemorrhagic Fever Viruses
We have reviewed the primary literature on the virucidal efficacy of microbicidal active ingredients, formulated microbicides, and physical inactivation approaches (heat, irradiation) for hemorrhagic fever viruses (HFVs) (arenaviruses, filoviruses ...
Raymond W. Nims, M. Khalid Ijaz
doaj +1 more source
Viral and Prion Infections Associated with Central Nervous System Syndromes in Brazil
Virus-induced infections of the central nervous system (CNS) are among the most serious problems in public health and can be associated with high rates of morbidity and mortality, mainly in low- and middle-income countries, where these manifestations ...
Ivanildo P. Sousa +6 more
doaj +1 more source
Nano‐ and Micro‐Sized Solid Materials Used as Antiviral Agents
Due to the rise of viral infections in humans and possible viral outbreaks, the use of nano‐ or micro‐sized materials as antiviral agents is rapidly increasing. This review explores their antiviral properties against RNA and DNA viruses, either as a prevention or a treatment tool, by delving into their mechanisms of action and how to properly assess ...
Orfeas‐Evangelos Plastiras +6 more
wiley +1 more source
Membranous Replication Factories Induced by Plus-Strand RNA Viruses
In this review, we summarize the current knowledge about the membranous replication factories of members of plus-strand (+) RNA viruses. We discuss primarily the architecture of these complex membrane rearrangements, because this topic emerged in the ...
Inés Romero-Brey, Ralf Bartenschlager
doaj +1 more source
Functional Information Stored in the Conserved Structural RNA Domains of Flavivirus Genomes [PDF]
The genus Flavivirus comprises a large number of small, positive-sense single-stranded, RNA viruses able to replicate in the cytoplasm of certain arthropod and/or vertebrate host cells.
Berzal-Herranz, Alfredo +3 more
core +1 more source
Amid the ongoing threat of emerging viral pathogens, host‐directed antivirals offer a strategy to overcome viral mutation and drug resistance. SB2960, a small‐molecule inducer of stress granules (SGs), exhibits potent broad‐spectrum antiviral activity with minimal cytotoxicity.
Wan Gi Byun +14 more
wiley +1 more source
West Nile virus (WNV) causes West Nile fever and encephalitis worldwide. Currently, there are no effective drugs or vaccines available in the market to treat WNV infection in humans.
Priyanka Singh Tomar +3 more
doaj +1 more source

