Results 31 to 40 of about 21,422 (217)

Synthesis of some novel 3-[ω–(substituted phenoxy/anilino/thiophenoxy/2-pyridylamino) alkoxy] flavones

Orbital: The Electronic Journal of Chemistry, 2012
Several α-(3-flavonyloxy)-ω-bromoalkanes (1) on treatment with substituted phenols, anilines, thiophenols and 2-aminopyridine resulted novel potentially bioactive 3-ω-substituted phenoxy (3a-t), anilino (4a-h), thiophenoxy (5a-d) and 2-pyridylamino (7a-c)
K. L. Ameta, R. S. Sodani, R. B. Bhandari, B. L. Verma   +3 more
doaj   +1 more source

Exploring the Formation of Polymers with Anti-Amyloid Properties within the 2′3′-Dihydroxyflavone Autoxidation Process

Antioxidants, 2022
Amyloid-β and α-synuclein aggregation into amyloid fibrils is linked to the onset and progression of Alzheimer’s and Parkinson’s diseases. While there are only a few disease-modifying drugs, it is essential to search for new, more effective ways to ...
Andrius Sakalauskas, Agne Janoniene, Gediminas Zvinys, Kamile Mikalauskaite, Mantas Ziaunys, Vytautas Smirnovas   +5 more
doaj   +1 more source

Multi‐tissue Metabolic GWAS and Drought‐Responsive Multi‐omics Reveal the Genetic Basis of the Quinoa Metabolome

Advanced Science, EarlyView.
A multi‐omics framework combining multitissue genome‐wide association studies, metabolomics, transcriptomics, proteomics, and functional validation uncovers the genetic basis of specialized metabolism in quinoa. The study identifies hundreds of metabolite‐associated loci, prioritizes candidate genes for saponin, betalain, and flavonoid biosynthesis ...
Julia von Steimker, Elodie L. Rey, Clara Stanschewski, Regina Wendenburg, Annabella Klemmer, Markéta Macho, Venkatesh P. Thirumalaikumar, Noha O. Saber, Aleksandra Skirycz, Alisdair R. Fernie, Mark Tester, Saleh Alseekh   +11 more
wiley   +1 more source

A Flavone-Based Solvatochromic Probe with A Low Expected Perturbation Impact on the Membrane Physical State

Molecules, 2020
The study of the cell membrane is an ambitious and arduous objective since its physical state is regulated by a series of processes that guarantee its regular functionality.
Simona Concilio, Miriam Di Martino, Anna Maria Nardiello, Barbara Panunzi, Lucia Sessa, Ylenia Miele, Federico Rossi, Stefano Piotto   +7 more
doaj   +1 more source

Comparison of Functional Components and Antioxidant Activities of Soy Sauces Brewed with Different Raw Materials

Shipin gongye ke-ji, 2023
Using black bean, soybean and soybean meal as raw materials, soy sauce was prepared by high-salt dilution method. The quality indexes, functional components and antioxidant activities of the three soy sauce were detected by conventional methods and ...
Chunhui YANG, Wenping WANG, Dandan XU, Yuqian CUI, Yan JU, Chunyan XU, Xiaoting LÜ   +6 more
doaj   +1 more source

Comprehensive Characterization of Acer truncatum Leaf Extract: Identification of Systemic Metabolites and Effects on Performance, Antioxidant Status, and Intestinal Microbiota in Laying Hens

Animal Research and One Health, EarlyView.
Dietary A. truncatum leaf extract is absorbed and improves laying performance in aged hens by enhancing systemic antioxidant capacity and modulating the gut microbiota. ABSTRACT The demand for natural feed additives is considerably increasing in the antibiotic‐free feed era.
Kailong Qin, Jiantao Yang, Minglu Gao, Xiaozhao Tao, Xin Yang, Yanli Liu, Xiaojun Yang   +6 more
wiley   +1 more source

Baicalein Induces G₂/M Cell Cycle Arrest Associated with ROS Generation and CHK2 Activation in Highly Invasive Human Ovarian Cancer Cells

Molecules, 2023
Ovarian cancer is a lethal gynecological cancer because drug resistance often results in treatment failure. The CHK2, a tumor suppressor, is considered to be an important molecular target in ovarian cancer due to its role in DNA repair.
Tzu-Chao Chuang, Wei-Syun Shao, Shih-Chung Hsu, Shou-Lun Lee, Ming-Ching Kao, Vinchi Wang   +5 more
doaj   +1 more source

Highly Potent Fluorogenic Ligands for Triplex DNA: 5‐Substituted 2‐(Naphthalen‐2‐yl)‐4H‐Chromen‐4‐Ones

Chemistry – A European Journal, EarlyView.
5‐Substituted 2‐(naphthalen‐2‐yl)‐4H‐chromen‐4‐ones are reported as a novel class of highly potent and selective triplex DNA ligands. These ligands induce triplex formation at submicromolar concentrations and inhibit enzymatic activity via ligand‐mediated triplex formation.
Nghia Tran, Landy Gu, Krege M. Christison, Kalee Thao, Liang Xue   +4 more
wiley   +1 more source

Flavones and Flavone Glycosides from Salvia macrosiphon Boiss.

Iranian journal of pharmaceutical research : IJPR, 2011
Salvia genus, which is generally called Maryam-Goli in the Persian language, belongs to Lamiaceae family and comprises 58 species in Iran. Four flavonoids plus a steroid compound were isolated from the ethyl acetate and methanol extracts of the aerial parts of Salvia macrosiphon Boiss, using different chromatographic methods on the silica gel and ...
Gohari, Ahmad Reza, Ebrahimi, Hakimeh, Saeidnia, Soodabeh, Foruzani, Mahdi, Ebrahimi, Puneh, Ajani, Yousef   +5 more
openaire   +2 more sources

Synthesis of the Core Tetracycle of the Spirobiflavonoid Daphnodorin C

European Journal of Organic Chemistry, EarlyView.
Core spirotetracycle of daphnodorin C: Oxidative ring contraction of benzofuro[3,2‐b]chromenones affords novel 2,3′‐spirobi[benzofuran]diones, rather than the isomeric spiroketals. The first synthesis of the spirobi[benzofuran]dione core structure of the spirobiflavonoid daphnodorin C is described.
Lukas Heemann, Peter G. Jones, Thomas Lindel   +2 more
wiley   +1 more source