Results 11 to 20 of about 343,905 (345)

Analysis of 2′-hydroxyflavanone (2HF) in mouse whole blood by HPLC–MS/MS for the determination of pharmacokinetic parameters

Frontiers in Chemistry, 2023
Given the lack of investments, structure, and difficulty of metabolite isolation, promising natural product studies do not progress to preclinical studies, such as pharmacokinetics.
Luiza F. O. Gervazoni, Gabriella Gonçalves-Ozorio, Taiana Ferreira-Paes, Aline C. A. Silva, Gabriel P. E. Silveira, Heliana M. Pereira, Douglas P. Pinto, Edézio F. Cunha-Junior, Elmo E. Almeida-Amaral   +8 more
doaj   +1 more source

Habitual intake of flavonoid subclasses and risk of colorectal cancer in two large prospective cohorts [PDF]

, 2016
Background: Flavonoids inhibit the growth of colon cancer cells in vitro. In a secondary analysis of a randomized controlled trial, the Polyp Prevention Trial, a higher intake of one sub-class, flavonols, was significantly associated with reduced risk of
Aedín Cassidy, Andrew T Chan, Arts, Bobe, Cassidy, Cassidy, Charles S Fuchs, Colditz, Cutler, DerSimonian, Devore, Edward L Giovannucci, Eric B Rimm, Feskanich, Fini, Gao, Giovannucci, Hirvonen, Hu, Jennifer H Lin, Kana Wu, Kandaswami, Katharina Nimptsch, Knekt, Knekt, Kyle, Lambert, Lee, Lin, Mahmoud, McCullough, Mingyang Song, Moon, Mursu, Park, Platz, Rich-Edwards, Rimm, Rossi, Rossi, Sacks, Salvini, Shuji Ogino, Simons, Stampfer, Theodoratou, Tobias Pischon, Voorrips, Walter C Willett, Wei, Willett, Willett, Willett, Williamson, Williamson, Woo, Xuehong Zhang, Yamauchi, Yang, Yu, Yuan, Zamora-Ros, Éilis J O’Reilly   +62 more
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Extract of Caesalpinia sappan L. as Antibacterial Feed Additive on Intestinal Microflora of Laying Quail

Journal of Experimental Life Science, 2017
Caesalpinia sappan L. is a phytobiotic plant that serves as an antibacterial. Active compound such as flavonoids in the C. sappan L. extract acts as an antibacterial. The protein food sources in Indonesia including poultry such as quail.
Anang Widigdyo, Eko Widodo, Irfan Hadji Djunaidi   +2 more
doaj   +1 more source

Megalurothrips usitatus Directly Causes the Black-Heads and Black-Tail Symptoms of Cowpea along with the Production of Insect-Resistance Flavonoids

Plants, 2023
The thrip (Megalurothrips usitatus) damages the flowers and pods of the cowpea, causing “black-heads and black-tails” (BHBT) symptoms and negatively affecting its economic value. However, the mechanism by which BHBT symptoms develop is still unknown. Our
Yunchuan He, Yang Gao, Hainuo Hong, Jiamei Geng, Qiulin Chen, Ying Zhou, Zengrong Zhu   +6 more
doaj   +1 more source

Deconjugation Kinetics of Glucuronidated Phase II Flavonoid Metabolites by B-glucuronidase from Neutrophils [PDF]

, 2010
Flavonoids are inactivated by phase II metabolism and occur in the body as glucuronides. Mammalian ß-glucuronidase released from neutrophils at inflammatory sites may be able to deconjugate and thus activate flavonoid glucuronides.
Arts, I.C.W., Bartholomé, R., Bast, A., Dagnelie, P.C., Haenen, G., Hollman, P.C.H., Keijer, J., Kroon, P.A., Needs, P.W., Roos, D.   +9 more
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Antioxidant Properties and Kidney Cell Protection by the Extracts of Curcuma longa, Artemisia princeps, Salicornia herbacea, and Schisandra chinesis

Fermentation, 2022
This study evaluated the antioxidant properties and kidney cell protection of medicinal plants as natural medicaments. A total of four medicinal plants including turmeric (TM), gangwha mugwort (GM), glasswort (GW), and omija (OM) were selected and ...
Jeong-Yeon On, Jeong-Mee Kim, Damini Kothari, Soo-Ki Kim   +3 more
doaj   +1 more source

Discovery of Quercetin and Its Analogs as Potent OXA-48 Beta-Lactamase Inhibitors

Frontiers in Pharmacology, 2022
Carbapenem resistance in Enterobacteriaceae caused by OXA-48 β-lactamase is a growing global health threat and has rapidly spread in many regions of the world. Developing inhibitors is a promising way to overcome antibiotic resistance. However, there are
Yuejuan Zhang, Yuejuan Zhang, Cheng Chen, Bin Cheng, Lei Gao, Lei Gao, Chuan Qin, Chuan Qin, Lixia Zhang, Xu Zhang, Xu Zhang, Jun Wang, Jun Wang, Yi Wan, Yi Wan   +14 more
doaj   +1 more source

Cognitive tests used in chronic adult human randomised controlled trial micronutrient and phytochemical intervention studies [PDF]

, 2010
In recent years there has been a rapid growth of interest in exploring the relationship between nutritional therapies and the maintenance of cognitive function in adulthood.
Anderson, Anna L. Macready, Balk, Burgess, Claire M. Williams, Clarke, Detterman, Eussen, Fournier, Ho, Ivers, Jeremy P. E. Spencer, Judi A. Ellis, Knapp, Laurie T. Butler, Lezak, Manly, Maylor, McDaniel, Orla B. Kennedy, Phillips, Rabbitt, Reitan, Rosen, Rugg, Santos, Wechsler, Wechsler, Wesnes   +28 more
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Diverse biological effects of glycosyltransferase genes from Tartary buckwheat [PDF]

, 2019
Background: Tartary buckwheat (Fagopyrum tataricum) is an edible cereal crop whose sprouts have been marketed and commercialized for their higher levels of anti-oxidants, including rutin and anthocyanin. UDP-glucose flavonoid glycosyltransferases (UFGTs)
Chen, Hui, Deng, Renyu, Dong, Qixin, Huang, Yunji, Li, Chenglei, Li, Qi, Lv, Bingbing, Shi, Guanlan, Shi, Jiaqi, Stael, Simon, Wu, Qi, Yao, Panfeng, Zhao, Haixia   +12 more
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Ensiling vine tea (Ampelopsis grossedentata) residue with Lactobacillus plantarum inoculant as an animal unconventional fodder

Journal of Integrative Agriculture, 2023
The study aimed to evaluate the application of silage fermentation in storing vine tea residue. Dynamic of fermentation-related product, chemical component and bacterial community of silage with or without Lactobacillus plantarum F1 inoculant were ...
Yuan WANG, Hong-zhang ZHOU, Yu GAO, Ning-wei WANG, Han LIU, Fu-yu YANG, Kui-kui NI   +6 more
doaj   +1 more source