Results 91 to 100 of about 41,055 (201)

Membership and behavior of ultra-low-diversity pathogen communities present in the gut of humans during prolonged critical illness. [PDF]

, 2014
UnlabelledWe analyzed the 16S rRNA amplicon composition in fecal samples of selected patients during their prolonged stay in an intensive care unit (ICU) and observed the emergence of ultra-low-diversity communities (1 to 4 bacterial taxa) in 30% of the ...
Alverdy, John C, Garfield, Kevin, Gilbert, Jack A, Kade, Matthew, Quensen, John, Shakhsheer, Baddr, Smith, Daniel, Tiedje, James, Tirrell, Matthew, Zaborin, Alexander, Zaborina, Olga   +10 more
core   +3 more sources

Transforming Treatment: The Impact of Bariatric Surgery on Oral Drug Absorption

Obesity Reviews, EarlyView.
ABSTRACT Obesity represents a significant threat to global public health, with an estimated 16% of adults worldwide (2022) being classified as people with obesity, with a body mass index of 30 or more. Bariatric surgery is regarded as the most effective treatment option for people with obesity, with the three main types of bariatric surgery being ...
Danielle Wigg, Andrea Edginton, Matthew D. Jones, Nikoletta Fotaki   +3 more
wiley   +1 more source

Cyclic AMP and Fluconazole Resistance in Saccharomyces cerevisiae [PDF]

Antimicrobial Agents and Chemotherapy, 2000
ABSTRACT Cyclic AMP (cAMP) is involved in the stress response in Saccharomyces cerevisiae . We show that cAMP is required for resistance to fluconazole in S. cerevisiae . In addition, activation of Ras2 , a regulator of cAMP generation, results in some ...
D P, Kontoyiannis, S, Rupp
openaire   +2 more sources

Infections in Chronic Lymphocytic Leukemia: Evolving Risks and Prevention Strategies

European Journal of Haematology, Volume 116, Issue 3, Page 204-214, March 2026.
ABSTRACT Infections remain a leading cause of morbidity and mortality in patients with chronic lymphocytic leukemia (CLL), reflecting both intrinsic immune dysfunction and therapy‐related immunosuppression. The pathogenesis of immunodeficiency in CLL is multifactorial: neoplastic B cells impair humoral immunity, T cells are functionally exhausted, and ...
Enrica Antonia Martino, Santino Caserta, Ernesto Vigna, Antonella Bruzzese, Nicola Amodio, Eugenio Lucia, Virginia Olivito, Caterina Labanca, Francesco Mendicino, Fortunato Morabito, Massimo Gentile   +10 more
wiley   +1 more source

Molecular Mechanism of Fluconazole Resistance among Clinical Isolates of Non albicans Candida Species in a Rural Tertiary Healthcare Centre of Central India: A Research Protocol

Journal of Clinical and Diagnostic Research
Introduction: The most common fungal infections are caused by Candida spp., and non albicans Candida (NAC) species are increasingly prevalent in India.
Gargi Mudey, Dipika Shaw
doaj   +1 more source

Symptomatic relapse of HIV-associated cryptococcal meningitis in South Africa: the role of inadequate secondary prophylaxis. [PDF]

, 2010
OBJECTIVES: Cryptococcal meningitis is the commonest cause of adult meningitis in Southern Africa. A sizeable proportion of this disease burden is thought to be due to symptomatic relapse of previously treated infection. We carried out a study to examine
Harrison, Thomas S, Jarvis, Joseph N, Meintjes, Graeme, Rebe, Kevin, Williams, Zomzi   +4 more
core   +3 more sources

Eradication of Candida albicans persister cell biofilm by the membranotropic peptide gH625 [PDF]

, 2020
Biofilm formation poses an important clinical trouble due to resistance to antimicrobial agents; therefore, there is an urgent demand for new antibiofilm strategies that focus on the use of alternative compounds also in combination with conventional ...
D'Alterio, A., de Alteriis, E., De Natale, A., Falanga, A., Galdiero, E., Galdiero, S., Guida, M., Lombardi, L., Siciliano, A.   +8 more
core   +1 more source

The resistance to fluconazole in patients with esophageal candidiasis [PDF]

Arquivos de Gastroenterologia, 2009
CONTEXT: Esophageal candidiasis is often observed in patients with risk factors for its development and fluconazole is the therapeutic choice for the treatment of this disease. OBJECTIVES: To determine its frequency, by performing upper digestive endoscopy; to determine Candida species involved in its pathogenesis and verify their distribution ...
Wilheim, Ana Botler, Miranda-Filho, Demócrito de Barros, Nogueira, Rodrigo Albuquerque, Rêgo, Rossana Sette de Melo, Lima, Kedma de Magalhães, Pereira, Leila Maria Moreira Beltrão   +5 more
openaire   +4 more sources

Characterization, Antimicrobial, and Antiproliferative Activities of Silver Nanoparticles Biosynthesized Using Terminalia phanerophlebia Engl. & Diels

Cell Biochemistry and Function, Volume 44, Issue 2, February 2026.
ABSTRACT The application of nanoparticles (NPs) as therapeutic strategies for treating microbial infections and cancer is gaining attention due to their physicochemical properties. In this study, we synthesized silver nanoparticles (AgNPs) from the aqueous extract of the roots and leaves of Terminalia phanerophlebia.
Folasade O. Banji‐Onisile, Nneka A. Akwu, Tosin A. Olasehinde, Ademola O. Olaniran   +3 more
wiley   +1 more source

Transcriptome assembly and profiling of Candida auris reveals novel insights into biofilm-mediated resistance [PDF]

, 2018
Candida auris has emerged as a significant global nosocomial pathogen. This is primarily due to its antifungal resistance profile but also its capacity to form adherent biofilm communities on a range of clinically important substrates.
Ben-Ami, Berkow, Berkow, Bizerra, Bongomin, Borman, Borman, Calvo, Chatterjee, Chowdhary, Defosse, Denning, Dominguez, Fisher, Fonseca, Fox, Fu, Grahl, Haas, Hager, Hashemi, Hunter, Jeffery-Smith, Kean, Kean, Kean, Kean, Kempf, Kordalewska, Kordalewska, Larkin, Liu, Liu, Lockhart, Lohse, Martínez, Mukherjee, Naglik, Naglik, Nailis, Nobile, Perfect, Pierce, Rajendran, Rajendran, Rajendran, Ramage, Ramage, Ramage, Rodrigues, Ruiz-Gaitán, Schelenz, Sherry, Sherry, Silva, Soldini, Taff, Taff, Tumbarello, Tunney, Winter, Zarnowski, Zhao, Zhao   +63 more
core   +4 more sources