Results 71 to 80 of about 2,379,902 (206)

Paediatric Tinea Capitis in New Zealand: A Case Series

Australasian Journal of Dermatology, EarlyView.
ABSTRACT We reviewed 41 children referred to a New Zealand regional dermatology service between 2016 and 2026 with scalp alopecia suspected to be tinea capitis. Microsporum canis accounted for 17 of the 24 dermatophytes isolated (71%), a distribution consistent with New Zealand series over the past seven decades and unlike the shift towards ...
Karen Koch
wiley   +1 more source

A Mechanism Study on the Synergistic Effects of Rifapentine and Fluconazole Against Fluconazole-Resistant Candida Albicans in Vitro

Heliyon, 2023
Candida albicans (C. albicans) is one of the most common clinical isolates of systemic fungal infection. Long-term and inappropriate use of antifungal drugs can cause fungal resistance, which poses a great challenge to the clinical treatment of fungal infections.
Yulian Wang, Yufei He, Tongkai Cai, Zhongwei Lei, Wenzhi Lei, Yongbing Cao, Jianhua Wu   +6 more
openaire   +3 more sources

Ocular and cutaneous infection due to Curvularia pseudobrachyspora in an immunosuppressed dog: Case report and in vitro antimycotic susceptibilities

Australian Veterinary Journal, EarlyView.
A 3‐year‐old male Border Collie diagnosed with immune‐mediated dermatopathy, managed with tapering prednisolone and cyclosporine, developed rapidly progressive ocular signs and additional cutaneous lesions. Histopathology, mycological culture, polymerase chain reaction and sequencing confirmed intraocular and cutaneous infection due to Curvularia ...
T Brasil‐Ervedosa, R Clark, J Granados‐Soler, C Palmieri, V Gonzalez‐Astudillo   +4 more
wiley   +1 more source

Flucytosine-fluconazole cross-resistance in purine-cytosine permease-deficient Candida lusitaniae clinical isolates: indirect evidence of a fluconazole uptake transporter

, 2003
An unusual interaction between flucytosine and fluconazole was observed when a collection of 60 Candida lusitaniae clinical isolates was screened for cross-resistance.
Noël, Thierry, Paumard, Patrick, Villard, Jean, Chastin, Christiane, François, Fabienne, Brèthes, Daniel   +5 more
core   +1 more source

Emergence of Trichophyton indotineae in Switzerland (2014–2025): Clinical analysis and antifungal susceptibility

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Trichophyton indotineae is an emerging dermatophyte associated with chronic, recalcitrant dermatophytosis and terbinafine resistance due to squalene epoxidase (SQLE) mutations. We analyzed clinical characteristics, antifungal susceptibility profiles, SQLE mutations, and treatment outcomes of cases diagnosed in ...
Annabel H. Lechner, Dennis D. Arnold, Philipp P. Bosshard   +2 more
wiley   +1 more source

Mitochondrial iron homeostasis is required for azole tolerance in Candida albicans

The FEBS Journal, EarlyView.
In Candida albicans, the deletion of MRS4, which encodes a mitochondrial iron importer, abolishes fluconazole tolerance and increases cidality during cotreatment with the iron chelator BPS, without altering MIC or synergy. Fluconazole‐treated mutants exhibit increased mitochondrial depolarisation, fragmentation and reduced mitochondrial density.
Wouter Van Genechten, Gauthier Cornips, Martine De Jonge, Rudy Vergauwen, Patrick Van Dijck   +4 more
wiley   +1 more source

Phenotypic and genomic characterization of azole resistance in Portuguese Candida parapsilosis isolates

Frontiers in Fungal Biology
IntroductionCandida parapsilosis is a clinically important etiological agent of systemic infections associated with hospital outbreaks, which prevalence has been increasing in the last decade.
Alexandru-Marian Papuc, Cristina Veríssimo, Helena Simões, Cristina Toscano, João Paulo Gomes, João Paulo Gomes, Verónica Mixão, Raquel Sabino, Raquel Sabino, Raquel Sabino   +9 more
doaj   +1 more source

Indifferent effect of nonsteroidal anti-inflammatory drugs (NSAIDs) combined with fluconazole against multidrug-resistant Candida auris [PDF]

Current Medical Mycology, 2019
Background and Purpose: Emergence and development of antifungal drug resistance in Candida species constitute a serious concern. Candida auris as an emerging multidrug-resistant fungus is the most important public health threat with high levels of ...
Fatemeh Ahangarkani, Sadegh Khodavaisy, Shahram Mahmoudi, Tahereh Shokohi, Mohammad Sadegh Rezai, Hamed Fakhim, Eric Dannaoui, Saharnaz Faraji, Anuradha Chowdhary, Jacques F. Meis, Hamid Badali   +10 more
doaj   +1 more source

Feasibility and clinical outcomes of routine point‐of‐care screening for opportunistic infections among people with advanced HIV disease in Guyana

HIV Medicine, EarlyView.
Abstract Objectives We evaluated the feasibility and outcomes of implementing comprehensive Point‐of‐care (POC) opportunistic infections (OIs) screening among people with Advanced HIV disease (AHD) in Guyana. Methods We conducted a prospective multicentre cohort study across seven sites between February 2024 and March 2025.
Antonio Camiro‐Zúñiga, Tariq Jagnarine, Divya Shivdas, Lakshmi Narain, Kwesi Vanccoten, Kampta Prashad, Abiola Jacobs, Quacy Grant, Mallika Mootoo, Narissa Lawerence, Suzanne Siebs, Escalada Rainier, Omar Sued, Freddy Perez   +13 more
wiley   +1 more source

Fluconazole exposure rather than clonal spreading is correlated with the emergence of Candida glabrata with cross-resistance to triazole antifungal agents

, 2014
The emergence of antifungal resistance in Candida species has raised concern in recent years, especially resistance toward triazole. Several newer triazole antifungal agents have been introduced which have a broader spectrum for fungal infections, such ...
陳宜君, Chen, Tun-Chieh;Chen, Yen-Hsu;Chen, Yee-Chun;Lu, Po-Liang   +1 more
core   +1 more source