mSphere, 2023 Candida glabrata is a prominent opportunistic fungal pathogen of humans. The increasing incidence of C. glabrata infections is attributed to both innate and acquired resistance to antifungals.
Andrew N. Gale +5 more
doaj +1 more source
First hospital outbreak of the globally emerging Candida auris in a European hospital [PDF]
, 2016 Background: Candida auris is a globally emerging multidrug resistant fungal pathogen causing nosocomial transmission. We report an ongoing outbreak of C. auris in a London cardio-thoracic center between April 2015 and July 2016.
Abdolrasouli, A +11 more
core +2 more sources
Drug-Resistant Candida glabrata Infection in Cancer Patients
Emerging Infectious Diseases, 2014 Cancer patients are at risk for candidemia, and increasing Candida spp. resistance poses an emerging threat. We determined rates of antifungal drug resistance, identified factors associated with resistance, and investigated the correlation between ...
Dimitrios Farmakiotis +2 more
doaj +1 more source
Set of Classical PCRs for Detection of Mutations in Candida glabrata FKS Genes Linked with Echinocandin Resistance [PDF]
, 2014 Clinical echinocandin resistance among Candida glabrata strains is increasing, especially in the United States. Antifungal susceptibility testing is considered mandatory to guide therapeutic decisions.
Afeltra, Javier +7 more
core +2 more sources
Microbiology Spectrum, 2021 Resistance to fluconazole is one of clinical characteristics most frequently challenging the treatment of invasive Candida auris infections, and is observed among >90% of all characterized clinical isolates. In this work, the native C. auris ERG11 allele
Jeffrey M. Rybak +5 more
doaj +1 more source
Adhesive Properties and Sensitivity to Antifungal Drugs of Candida Albicans, Which Are Released From Patients of Gastroenterological Profile with Candidiasis of the Mucosa of the Upper Part of the Digestive Tract [PDF]
, 2016 Candida albicans were released from 146 loci from 89 patients in order to perform the investigation. The fourth stage of contamination by Candida albicans in the scrape from the tongue and candidiasis of the esophagus or /and the stomach during ...
Kushnirenko, I. (Inessa)
core +2 more sources
Potent In Vitro Synergism of Fluconazole and Osthole against Fluconazole-Resistant Candida albicans [PDF]
Antimicrobial Agents and Chemotherapy, 2017 ABSTRACT Osthole is a natural coumarin that exhibits wide biological and pharmacological activities such as neuroprotective, osteogenic, immunomodulation, antitumor, and anti-inflammatory effects. In this study, we investigated the antifungal effects of osthole in vitro . A checkerboard microdilution assay
De-Dong, Li +7 more
openaire +2 more sources
Cryptococcal Meningitis Diagnostics and Screening in the Era of Point-of-Care Laboratory Testing. [PDF]
, 2019 Over the past ten years, standard diagnostics for cryptococcal meningitis in HIV-infected persons have evolved from culture to India ink to detection of cryptococcal antigen (CrAg), with the recent development and distribution of a point-of-care lateral ...
Beyene, T +5 more
core +1 more source
Successful Treatment of Fluconazole-Resistant Oropharyngeal Candidiasis by a Combination of Fluconazole and Terbinafine [PDF]
Clinical Diagnostic Laboratory Immunology, 1999 ABSTRACT Increasing incidence of resistance to conventional antifungal therapy has demanded that novel therapies be introduced. Recent in vitro studies have shown that combinations involving azoles and allylamines may be effective in inhibiting fluconazole-resistant fungi.
M A, Ghannoum, B, Elewski
openaire +2 more sources
Virulence factors of fluconazole-susceptible and fluconazole-resistant Candida albicans after antimicrobial photodynamic therapy [PDF]
Lasers in Medical Science, 2017 This study evaluated the effects of antimicrobial photodynamic therapy (aPDT) mediated by Photodithazine® (PDZ) and LED light on the virulence factors of fluconazole-susceptible (CaS) and fluconazole-resistant (CaR) Candida albicans. Standardized suspensions of strains were prepared (107), and after 48 h of biofilm formation, these strains were ...
Alves, Fernanda +5 more
openaire +4 more sources