Results 31 to 40 of about 27,453 (182)

Risk Factors for Fluconazole-Resistant Candidemia [PDF]

Antimicrobial Agents and Chemotherapy, 2010
ABSTRACT Previous studies have sought to determine the risk factors associated with candidemia caused by non- albicans Candida spp. or with potentially fluconazole-resistant Candida spp. ( C. glabrata and C. krusei ).
José, Garnacho-Montero, Ana, Díaz-Martín, Emilio, García-Cabrera, Maite, Ruiz Pérez de Pipaón, Clara, Hernández-Caballero, Javier, Aznar-Martín, José M, Cisneros, Carlos, Ortiz-Leyba   +7 more
openaire   +2 more sources

Ambroxol Hydrochloride Combined with Fluconazole Reverses the Resistance of Candida albicans to Fluconazole [PDF]

Frontiers in Cellular and Infection Microbiology, 2017
In this study, we found that ambroxol hydrochloride (128 μg/mL) exhibits synergistic antifungal effects in combination with fluconazole (2 μg/mL) against resistant planktonic Candida albicans (C. albicans) cells. This combination also exhibited synergistic effects against resistant C.
Li, Xiuyun, Zhao, Yuanhao, Huang, Xin, Yu, Cuixiang, Yang, Yilei, Sun, Shujuan   +5 more
openaire   +2 more sources

Successful Treatment of Fluconazole-Resistant Oropharyngeal Candidiasis by a Combination of Fluconazole and Terbinafine [PDF]

Clinical Diagnostic Laboratory Immunology, 1999
ABSTRACT Increasing incidence of resistance to conventional antifungal therapy has demanded that novel therapies be introduced. Recent in vitro studies have shown that combinations involving azoles and allylamines may be effective in inhibiting fluconazole-resistant fungi.
M A, Ghannoum, B, Elewski
openaire   +2 more sources

Biofilm formation by fluconazole-resistant Candida albicans strains is inhibited by fluconazole [PDF]

Journal of Antimicrobial Chemotherapy, 2007
The fungal pathogen Candida albicans forms biofilms on implanted medical devices, resulting in infections with high mortality. Fully developed biofilms, which are adherent communities of microorganisms, characteristically exhibit high resistance to antimicrobial drugs, making treatment of device-associated infection problematic.
Igor, Bruzual, Perry, Riggle, Susan, Hadley, Carol A, Kumamoto   +3 more
openaire   +2 more sources

Hsp90 governs dispersion and drug resistance of fungal biofilms [PDF]

, 2011
Fungal biofilms are a major cause of human mortality and are recalcitrant to most treatments due to intrinsic drug resistance. These complex communities of multiple cell types form on indwelling medical devices and their eradication often requires ...
Ramage Gordon, Lopez-Ribot, J.L., Rajendran Ranjith, Ramage, G., Leah E. Cowen, Uppuluri Priya, Robbins, N., Priya Uppuluri, Rajendran, R., Andes, D., Jose L Lopez-Ribot, David Andes, Leah E Cowen, Nicole Robbins, Uppuluri, P., Robbins Nicole, Nett Jeniel, Lopez-Ribot Jose L., Jose L. Lopez-Ribot, Cowen, L.E., Nett, J., Ranjith Rajendran, Gordon Ramage, Jeniel Nett, Andes David, Cowen Leah E.   +25 more
core   +1 more source

SWL-1 Reverses Fluconazole Resistance in Candida albicans by Regulating the Glycolytic Pathway

Frontiers in Microbiology, 2020
Candida albicans is a ubiquitous clinical fungal pathogen. Prolonged use of the first-line antifungal agent fluconazole (FLC) has intensified fungal resistance and limited its effectiveness for the treatment of fungal infections.
Xiao-Ning Li, Xiao-Ning Li, Lu-Mei Zhang, Lu-Mei Zhang, Yuan-Yuan Wang, Yi Zhang, Yi Zhang, Ze-Hua Jin, Ze-Hua Jin, Jun Li, Jun Li, Rui-Rui Wang, Rui-Rui Wang, Wei-Lie Xiao   +13 more
doaj   +1 more source

Species Distribution and in Vitro Antifungal Susceptibility of Oral Yeast Isolates from Tanzanian HIV-Infected Patients With Primary and Recurrent Oropharyngeal Candidiasis. [PDF]

, 2008
\ud In Tanzania, little is known on the species distribution and antifungal susceptibility profiles of yeast isolates from HIV-infected patients with primary and recurrent oropharyngeal candidiasis.
Rijs Antonius JMM, Mugusi Ferdinand, Simon Elison NM, van der Ven, A.J., Rijs, A.J.M.M, Verweij, P.E., Verweij, P.E, Simon, Elison N M, Matee, Mecky I N, Palenstein Helderman, W.H. van, Moshi, M.J, Van Palenstein Helderman, W.H, Moshi, Mainen J, Rijs, Antonius J M M, Hamza, O.J.M., Wim Helderman, Frans HM Mikx, Simon, E.N.M., Verweij, Paul E, Ferdinand Mugusi, Mugusi, Ferdinand, Hamza, Omar J M, van der Ven André JAM, Antonius JMM Rijs, Mikx, F.H.M., Rijs, A.J.M.M., Elison NM Simon, Ven, A.J.A.M. van der, Mikx Frans HM, Matee Mecky IN, Matee, M.I.N, Simon, E.N., Verweij Paul E, Paul E Verweij, Helderman, W.H.P., Moshi, M.J., Moshi Mainen J, Simon, E.N.M, Helderman, Wim H van Palenstein, André JAM van der Ven, Mecky IN Matee, Mikx, Frans H M, Omar JM Hamza, Mugusi, F., van der Ven, André J A M, Mainen J Moshi, Matee, M.I.N., Mikx, F.H.M, Van der Ven, A.J.A.M, Hamza, O.J.M, Hamza Omar JM, Helderman Wim   +51 more
core   +1 more source

In vitro activities of antifungal agents alone and in combination against fluconazole-susceptible and -resistant strains of Candida dubliniensis

Brazilian Journal of Infectious Diseases, 2012
In the present study we used two groups of Candida dubliniensis strains: one containing fluconazole-susceptible clinical isolates and another containing fluconazole-resistant laboratory derivative from the former to examine the changes on susceptibility ...
Liliane Alves Scheid, Débora Alves Nunes Mario, Thaís Felli Kubiça, Janio Morais Santurio, Sydney Hartz Alves   +4 more
doaj   +1 more source

Cost effectiveness of cryptococcal antigen screening as a strategy to prevent HIV-associated cryptococcal meningitis in South Africa. [PDF]

, 2013
OBJECTIVES: Cryptococcal meningitis (CM)-related mortality may be prevented by screening patients for sub-clinical cryptococcal antigenaemia (CRAG) at antiretroviral-therapy (ART) initiation and pre-emptively treating those testing positive.
Thomas S Harrison, Wood, R, Meintjes, Graeme, Joseph N. Jarvis, Joseph N. Jarvis (435279), Harrison Thomas S., Lawn, Stephen D, Cleary, Susan, Robin Wood, Joseph N Jarvis, Stephen D Lawn, Jarvis, JN, Jarvis Joseph N., Meintjes Graeme, Thomas S. Harrison (222993), Graeme Meintjes (221054), Stephen D. Lawn (116037), Robin Wood (4924), Lawn Stephen D., Susan Cleary, Susan Cleary (158497), Stephen D. Lawn, Harrison, Thomas S, Cleary, S, Wood Robin, Harrison, TS, Thomas S. Harrison, Cleary Susan, Lawn, SD, Graeme Meintjes, Meintjes, G, Jarvis, Joseph N, Wood, Robin   +32 more
core   +1 more source

Emergence of fluconazole-resistant candida infections in diabetic foot ulcers: Implications for public health

Indian Journal of Community Medicine, 2019
Background: It is well documented in the literature that fungal infections are common in diabetic foot ulcers (DFUs). This has led to an overuse of antifungal agents, namely fluconazole, with a consequent risk of emergence of resistance to this drug ...
Chankramath S Arun, Priyanka Raju, Vivek Lakshmanan, Anil Kumar, Arun Bal, Harish Kumar   +5 more
doaj   +1 more source