Results 31 to 40 of about 2,213,888 (211)

CAQ Corner: Basic concepts of transplant immunology

, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

CAQ Corner: Immune‐mediated complications

, 2022
Liver Transplantation, EarlyView.
Mary Thomson, John R. Lake
wiley   +1 more source

SWL-1 Reverses Fluconazole Resistance in Candida albicans by Regulating the Glycolytic Pathway

Frontiers in Microbiology, 2020
Candida albicans is a ubiquitous clinical fungal pathogen. Prolonged use of the first-line antifungal agent fluconazole (FLC) has intensified fungal resistance and limited its effectiveness for the treatment of fungal infections.
Xiao-Ning Li, Xiao-Ning Li, Lu-Mei Zhang, Lu-Mei Zhang, Yuan-Yuan Wang, Yi Zhang, Yi Zhang, Ze-Hua Jin, Ze-Hua Jin, Jun Li, Jun Li, Rui-Rui Wang, Rui-Rui Wang, Wei-Lie Xiao   +13 more
doaj   +1 more source

Hsp90 governs dispersion and drug resistance of fungal biofilms [PDF]

, 2011
Fungal biofilms are a major cause of human mortality and are recalcitrant to most treatments due to intrinsic drug resistance. These complex communities of multiple cell types form on indwelling medical devices and their eradication often requires ...
Ramage Gordon, Lopez-Ribot, J.L., Rajendran Ranjith, Ramage, G., Leah E. Cowen, Uppuluri Priya, Robbins, N., Priya Uppuluri, Rajendran, R., Andes, D., Jose L Lopez-Ribot, David Andes, Leah E Cowen, Nicole Robbins, Uppuluri, P., Robbins Nicole, Nett Jeniel, Lopez-Ribot Jose L., Jose L. Lopez-Ribot, Cowen, L.E., Nett, J., Ranjith Rajendran, Gordon Ramage, Jeniel Nett, Andes David, Cowen Leah E.   +25 more
core   +2 more sources

A Prospective Longitudinal Study of the Clinical Outcomes from Cryptococcal Meningitis following Treatment Induction with 800 mg Oral Fluconazole in Blantyre, Malawi [PDF]

, 2013
Introduction: Cryptococcal meningitis is the most common neurological infection in HIV infected patients in Sub Saharan Africa, where gold standard treatment with intravenous amphotericin B and 5 flucytosine is often unavailable or difficult to ...
Mavuto Mukaka, Rothe, Camilla, Feasey, NA, Tom Harrison, van Oosterhout Joep J., Denis, Brigitte, Lalloo David G., Goodson, P, Rothe, C, Jean Chikafa, Sloan, DJ, Goodson, Patrick, Nicholas A Feasey, Mukaka, Mavuto, Joep J van Oosterhout, Lalloo, DG, Allain, T, Heyderman Robert S., Camilla Rothe, Harrison, T, Sloan Derek J., Harrison, Tom, Harrison Tom, Sloan, Derek J., Allain Theresa, Mukaka, M, Lalloo, David G., Theresa Allain, Goodson Patrick, Denis, B, van Oosterhout, JJ, Chikafa, Jean, Derek J Sloan, David G Lalloo, Chikafa, J, Patrick Goodson, Brigitte Denis, Rothe Camilla, Robert S Heyderman, Feasey Nicholas A., Chikafa Jean, van Oosterhout, Joep J., Mukaka Mavuto, Allain, Theresa, Feasey, Nick; id_orcid, Heyderman, RS, Feasey, Nicholas A., Denis Brigitte, Lalloo, David; id_orcid, Heyderman, Robert S.   +49 more
core   +1 more source

In vitro activities of antifungal agents alone and in combination against fluconazole-susceptible and -resistant strains of Candida dubliniensis

Brazilian Journal of Infectious Diseases, 2012
In the present study we used two groups of Candida dubliniensis strains: one containing fluconazole-susceptible clinical isolates and another containing fluconazole-resistant laboratory derivative from the former to examine the changes on susceptibility ...
Liliane Alves Scheid, Débora Alves Nunes Mario, Thaís Felli Kubiça, Janio Morais Santurio, Sydney Hartz Alves   +4 more
doaj   +1 more source

Evolution of Fluconazole Resistance in Candida albicans [PDF]

, 2000
29 pages, 1 article*Evolution of Fluconazole Resistance in Candida albicans* (Nayadike, Nnaemeka; Greenblatt, Aaron; Ortega, Omayra; Engmen, Martin; Wirkus, Steven) 29 ...
Greenblatt, Aaron, Ortega, Omayra, Wirkus, Steven, Cornell University. Dept. of Biological Statistics and Computational Biology., Cornell University. Biometrics Unit., Cornell University. Dept. of Biometrics., Engmen, Martin, Nayadike, Nnaemeka   +7 more
core   +6 more sources

A prospective study of mortality from cryptococcal meningitis following treatment induction with 1200 mg oral fluconazole in Blantyre, Malawi. [PDF]

, 2014
OBJECTIVE: We have previously reported high ten-week mortality from cryptococcal meningitis in Malawian adults following treatment-induction with 800 mg oral fluconazole (57% [33/58]).
Allain, TJ, Rothe, Camilla, Jassi, Chikondi, Feasey, NA, Gnanadurai, Roshina, Feasey, Nicholas A, Lalloo David G., Goodson, P, Gaskell Katherine M., Harrison Thomas S., Rothe, C, Sloan, DJ, Goodson, Patrick, Katherine M Gaskell, Nicholas A Feasey, Lalloo, DG, Heyderman Robert S., Camilla Rothe, Lalloo, David G, Sloan Derek J., Gaskell, Katherine M, Sloan, Derek J, Jassi, C, Roshina Gnanadurai, Gaskell, KM, Jassi Chikondi, Harrison, Thomas S, Sloan, Derek J., Gaskell, Katherine M., Harrison, TS, Lalloo, David G., Harrison, Thomas S., Heyderman, Robert S, Goodson Patrick, Allain Theresa J., Thomas S Harrison, Chikondi Jassi, Derek J Sloan, David G Lalloo, Gnanadurai, R, Patrick Goodson, Rothe Camilla, Robert S Heyderman, Gnanadurai Roshina, Allain, Theresa J, Feasey Nicholas A., Allain, Theresa J., Theresa J Allain, Feasey, Nick; id_orcid, Heyderman, RS, Feasey, Nicholas A., Lalloo, David; id_orcid, Heyderman, Robert S.   +52 more
core   +1 more source

AMBITION-cm : intermittent high dose AmBisome on a high dose fluconazole backbone for cryptococcal meningitis induction therapy in sub-Saharan Africa : study protocol for a randomized controlled trial [PDF]

, 2015
Cryptococcal meningitis (CM) is a leading cause of mortality among HIV-infected individuals in Africa. Poor outcomes from conventional antifungal therapies, unavailability of flucytosine, and difficulties administering 14 days of amphotericin B are key ...
Leeme, Tshepo, Síle F. Molloy, Changalucha, John M., Molefi, Mooketsi, Molloy, Síle F, Meintjes, Graeme, Molloy, Síle F., Goldberg, Drew W, John R. Perfect, Drew W. Goldberg, Kalluvya, Samuel, Cainelli, Francesca, Letang, Emili, Ndhlovu, Chiratidzo E, Perfect, John R, Ndhlovu, Chiratidzo E., Bisson, Gregory P., Miriam Haverkamp, Burton, Rosie, Rosie Burton, Tariro Makadzange, Harrison, Thomas S, Francesca Cainelli, Hope, William, Haverkamp, Miriam, Chiratidzo E. Ndhlovu, Harrison, Thomas S., Jarvis, Joseph N., Chofle, Awilly A, William Hope, Jarvis, Joseph N, Changalucha, John M, Fenner, Lukas, Perfect, John R., Makadzange, Tariro, Joseph N. Jarvis, Tshepo Leeme, Mooketsi Molefi, Nametso Lekwape, Lekwape, Nametso, John M. Changalucha, Emili Letang, Goldberg, Drew W., Lukas Fenner, Bisson, Gregory P, Awilly A. Chofle, Samuel Kalluvya, Thomas S. Harrison, Graeme Meintjes, Chofle, Awilly A., Gregory P. Bisson   +50 more
core   +2 more sources

Whole Genome Sequencing Shows Genetic Diversity, as Well as Clonal Complex and Gene Polymorphisms Associated with Fluconazole Non-Susceptible Isolates of Candida tropicalis

Journal of Fungi, 2022
Resistance to azoles in Candida tropicalis is increasing and may be mediated by genetic characteristics. Using whole genome sequencing (WGS), we examined the genetic diversity of 82 bloodstream C.
Caitlin Keighley, Mailie Gall, Sebastiaan J. van Hal, Catriona L. Halliday, Louis Yi Ann Chai, Kean Lee Chew, Chayanika Biswas, Monica A. Slavin, Wieland Meyer, Vitali Sintchenko, Sharon C. A. Chen   +10 more
doaj   +1 more source