Results 21 to 30 of about 27,453 (182)

Impact of milbemycin oxime on fluconazole resistance in <i>Candida auris</i>. [PDF]

JAC Antimicrob Resist
Candida auris is a pathogenic yeast that can develop resistance to multiple antifungals, particularly to azoles (e.g. fluconazole). Milbemycin oxime potentiates the effect of fluconazole against Candida spp.
Aubry L, Brandalise D, Louvet M, Coste AT, Sanglard D, Lamoth F, Li J.   +6 more
europepmc   +2 more sources

Fluconazole resistance in Candida albicans: a review of mechanisms.

European review for medical and pharmacological sciences, 2004
Antifungal agents have greatly contributed to the improvement of public health. Nevertheless, antifungal resistant pathogens have increased during the past decade, becoming a serious concern. Candida albicans has been the most extensively studied pathogen in antifungal resistance because of their morbidity and mortality associated with infections in ...
CASALINUOVO, IDA ANTONIA, DI FRANCESCO, PAOLO, GARACI, ENRICO   +2 more
core   +5 more sources

Ibuprofen-Mediated Reversal of Fluconazole Resistance in Clinical Isolates of Candida [PDF]

Journal of Clinical and Diagnostic Research, 2015
Introduction: In view of the increasing prevalence of invasive Candidiasis in today’s health-care scenario and the emergence of fluconazole resistance among clinical isolates of Candida, we sought to determine if Ibuprofen could elicit a reversal of ...
Monika Sharma, Debasis Biswas, Aarti Kotwal, Bhaskar Thakuria, Barnali Kakati, Bhupendra Singh Chauhan, Abhishek Patras   +6 more
doaj   +1 more source

Fluconazole resistance in Candida glabrata [PDF]

Antimicrobial Agents and Chemotherapy, 1993
We report a case of infection with Candida glabrata in which the organism became resistant to fluconazole and in which pre- and posttreatment isolates were available for comparison. The organism was cross-resistant to ketoconazole and itraconazole, in common with other azole-resistant yeasts.
C A, Hitchcock, G W, Pye, P F, Troke, E M, Johnson, D W, Warnock   +4 more
openaire   +2 more sources

Synergistic Effects of Amiodarone and Fluconazole on Candida tropicalis Resistant to Fluconazole [PDF]

Antimicrobial Agents and Chemotherapy, 2013
ABSTRACT There have recently been significant increases in the prevalence of systemic invasive fungal infections. However, the number of antifungal drugs on the market is limited in comparison to the number of available antibacterial drugs. This fact, coupled with the increased frequency of cross-resistance, makes it necessary to
Cecília Rocha, da Silva, João Batista, de Andrade Neto, José Júlio Costa, Sidrim, Maria Rozzelê Ferreira, Angelo, Hemerson Iury Ferreira, Magalhães, Bruno Coêlho, Cavalcanti, Raimunda Sâmia Nogueira, Brilhante, Danielle Silveira, Macedo, Manoel Odorico, de Moraes, Marina Duarte Pinto, Lobo, Thalles Barbosa, Grangeiro, Hélio Vitoriano, Nobre Júnior   +11 more
openaire   +2 more sources

Fluconazole Assists Berberine To Kill Fluconazole-Resistant Candida albicans [PDF]

Antimicrobial Agents and Chemotherapy, 2013
ABSTRACT It was found in our previous study that berberine (BBR) and fluconazole (FLC) used concomitantly exhibited a synergism against FLC-resistant Candida albicans in vitro . The aim of the present study was to clarify how BBR and FLC worked synergistically and the underlying mechanism ...
De-Dong, Li, Yi, Xu, Da-Zhi, Zhang, Hua, Quan, Eleftherios, Mylonakis, Dan-Dan, Hu, Ming-Bang, Li, Lan-Xue, Zhao, Liang-Hua, Zhu, Yan, Wang, Yuan-Ying, Jiang   +10 more
openaire   +2 more sources

The resistance to fluconazole in patients with esophageal candidiasis [PDF]

Arquivos de Gastroenterologia, 2009
CONTEXT: Esophageal candidiasis is often observed in patients with risk factors for its development and fluconazole is the therapeutic choice for the treatment of this disease. OBJECTIVES: To determine its frequency, by performing upper digestive endoscopy; to determine Candida species involved in its pathogenesis and verify their distribution ...
Wilheim, Ana Botler, Miranda-Filho, Demócrito de Barros, Nogueira, Rodrigo Albuquerque, Rêgo, Rossana Sette de Melo, Lima, Kedma de Magalhães, Pereira, Leila Maria Moreira Beltrão   +5 more
openaire   +4 more sources

The S862C amino acid change in CpMrr1 confers fluconazole resistance in <i>Candida parapsilosis</i>. [PDF]

JAC Antimicrob Resist
Background: Candida parapsilosis is an opportunistic pathogen with increasing rates of resistance to fluconazole and voriconazole. Recently, in an outbreak at the Azienda Ospedaliero-Universitaria Pisana, a new amino acid substitution, S862C in the ...
Franconi I, Poma N, Rizzato C, Maltinti L, Falcone M, Tavanti A, Lupetti A.   +6 more
europepmc   +2 more sources

Candida norvegensis: a fluconazole-resistant species [PDF]

Antimicrobial Agents and Chemotherapy, 1997
Candida norvegensis has been an unusual cause of infections in humans. In Norway this species was isolated from eight patients from 1990 to 1996 and was of probable pathogenic significance in four of them. All isolates were resistant to fluconazole. The same was true for two C. norvegensis isolates from before 1940, and it is therefore assumed that the
P, Sandven, K, Nilsen, A, Digranes, T, Tjade, J, Lassen   +4 more
openaire   +2 more sources

Fluconazole-resistant Candida parapsilosis: A new emerging threat in the fungi arena

Frontiers in Fungal Biology, 2022
Candida parapsilosis is a leading cause of invasive candidiasis in southern Europe, Latin America and Asia. C. parapsilosis has been mostly considered susceptible to triazoles, but fluconazole resistance is on the rise in some countries.
Pilar Escribano, Pilar Escribano, Jesús Guinea, Jesús Guinea, Jesús Guinea   +4 more
doaj   +1 more source