Results 21 to 30 of about 2,379,902 (206)

Molecular Evaluation of the mRNA Expression of the ERG11, ERG3, CgCDR1, and CgSNQ2 Genes Linked to Fluconazole Resistance in Candida glabrata in a Colombian Population [PDF]

Journal of Fungi
Introduction: The study of Candida glabrata genes associated with fluconazole resistance, from a molecular perspective, increases the understanding of the phenomenon with a view to its clinical applicability.
Leidy Yurany Cárdenas Parra, Ana Elisa Rojas Rodríguez, Jorge Enrique Pérez Cárdenas, Juan Manuel Pérez-Agudelo   +3 more
doaj   +2 more sources

Fluconazole resistance in Candida albicans: a review of mechanisms.

European review for medical and pharmacological sciences, 2004
Antifungal agents have greatly contributed to the improvement of public health. Nevertheless, antifungal resistant pathogens have increased during the past decade, becoming a serious concern. Candida albicans has been the most extensively studied pathogen in antifungal resistance because of their morbidity and mortality associated with infections in ...
CASALINUOVO, IDA ANTONIA, DI FRANCESCO, PAOLO, GARACI, ENRICO   +2 more
core   +7 more sources

Fingolimod potentiates the antifungal activity of fluconazole against fluconazole-resistant Candida auris

Frontiers in Cellular and Infection Microbiology
Candida auris has emerged as a critical nosocomial pathogen that particularly affects immunocompromised and critically ill patients in intensive care units, and it is associated with high mortality.
Ji-Hui Bae, Yong-Bin Eom, Yong-Bin Eom
doaj   +4 more sources

Impact of milbemycin oxime on fluconazole resistance in <i>Candida auris</i>. [PDF]

JAC Antimicrob Resist
Candida auris is a pathogenic yeast that can develop resistance to multiple antifungals, particularly to azoles (e.g. fluconazole). Milbemycin oxime potentiates the effect of fluconazole against Candida spp.
Aubry L, Brandalise D, Louvet M, Coste AT, Sanglard D, Lamoth F, Li J.   +6 more
europepmc   +2 more sources

The assessment of therapeutic response of oropharyngeal and oesophageal candidiasis in AIDS using a new scoring system: studies with D0870. [PDF]

, 1999
We developed and compared five scoring systems designed to quantitate therapeutic response in cases of oropharyngeal candidiasis. We utilized prospectively collected data on 114 patients treated with several doses of the azole D0870.
Williams, Keith, Percy, Meryl, Atkinson, Gill, Denning, David W., Hollis, Sally, Hood, Stephen V.   +5 more
core   +4 more sources

Fluconazole resistance in Candida glabrata [PDF]

Antimicrobial Agents and Chemotherapy, 1993
We report a case of infection with Candida glabrata in which the organism became resistant to fluconazole and in which pre- and posttreatment isolates were available for comparison. The organism was cross-resistant to ketoconazole and itraconazole, in common with other azole-resistant yeasts.
C A, Hitchcock, G W, Pye, P F, Troke, E M, Johnson, D W, Warnock   +4 more
openaire   +2 more sources

Synergistic Effects of Amiodarone and Fluconazole on Candida tropicalis Resistant to Fluconazole [PDF]

Antimicrobial Agents and Chemotherapy, 2013
ABSTRACT There have recently been significant increases in the prevalence of systemic invasive fungal infections. However, the number of antifungal drugs on the market is limited in comparison to the number of available antibacterial drugs. This fact, coupled with the increased frequency of cross-resistance, makes it necessary to
Cecília Rocha, da Silva, João Batista, de Andrade Neto, José Júlio Costa, Sidrim, Maria Rozzelê Ferreira, Angelo, Hemerson Iury Ferreira, Magalhães, Bruno Coêlho, Cavalcanti, Raimunda Sâmia Nogueira, Brilhante, Danielle Silveira, Macedo, Manoel Odorico, de Moraes, Marina Duarte Pinto, Lobo, Thalles Barbosa, Grangeiro, Hélio Vitoriano, Nobre Júnior   +11 more
openaire   +2 more sources

Ibuprofen-Mediated Reversal of Fluconazole Resistance in Clinical Isolates of Candida [PDF]

Journal of Clinical and Diagnostic Research, 2015
Introduction: In view of the increasing prevalence of invasive Candidiasis in today’s health-care scenario and the emergence of fluconazole resistance among clinical isolates of Candida, we sought to determine if Ibuprofen could elicit a reversal of ...
Monika Sharma, Debasis Biswas, Aarti Kotwal, Bhaskar Thakuria, Barnali Kakati, Bhupendra Singh Chauhan, Abhishek Patras   +6 more
doaj   +1 more source

Genomic Variation-Mediating Fluconazole Resistance in Yeast. [PDF]

Biomolecules, 2022
Fungal infections pose a serious and growing threat to public health. These infections can be treated with antifungal drugs by killing hazardous fungi in the body. However, the resistance can develop over time when fungi are exposed to antifungal drugs by generating genomic variations, including mutation, aneuploidy, and loss of heterozygosity.
Wang WY, Cai HQ, Qu SY, Lin WH, Liang CC, Liu H, Xie ZX, Yuan YJ.   +7 more
europepmc   +4 more sources

Fluconazole Assists Berberine To Kill Fluconazole-Resistant Candida albicans [PDF]

Antimicrobial Agents and Chemotherapy, 2013
ABSTRACT It was found in our previous study that berberine (BBR) and fluconazole (FLC) used concomitantly exhibited a synergism against FLC-resistant Candida albicans in vitro . The aim of the present study was to clarify how BBR and FLC worked synergistically and the underlying mechanism ...
De-Dong, Li, Yi, Xu, Da-Zhi, Zhang, Hua, Quan, Eleftherios, Mylonakis, Dan-Dan, Hu, Ming-Bang, Li, Lan-Xue, Zhao, Liang-Hua, Zhu, Yan, Wang, Yuan-Ying, Jiang   +10 more
openaire   +2 more sources