Results 61 to 70 of about 27,610 (210)

Reverse genetics in Candida albicans predicts ARF cycling is essential for drug resistance and virulence [PDF]

, 2010
Peer ...
Mullick, Alaka, Malcolm Whiteway, Jansen, Gregor, Whiteway, Malcolm, David Y Thomas, Harcus Doreen, Lee Anna Y., Vanier, Ghyslaine, Lee, Anna Y., Thomas, David Y, Michael Hallett, Vanier Ghyslaine, Munro, Carol A., Elias Epp, Epp Elias, Gregor Jansen, Thomas, David Y., Ghyslaine Vanier, Jansen Gregor, Harcus, Doreen, Anna Y Lee, Alaka Mullick, Hallett, Michael, Lee, Anna Y, Thomas David Y., Hallett Michael, Whiteway Malcolm, Carol A Munro, Mullick Alaka, Epp, Elias, Don C Sheppard, Sheppard Don C., Munro Carol A., Doreen Harcus, Sheppard, Don C, Sheppard, Don C., Munro, Carol A   +36 more
core   +1 more source

complex isolates: Increase in fluconazole resistance in 21 years [PDF]

, 2021
Background Candida parapsilosis complex consists of three species, the prevalence and geographical distribution of which might vary. Increasing rates of fluconazole resistance among C.
Gülmez Kıvanç, Dolunay, Dolunay Gülmez, Arıkan Akdağlı, Sevtap, Selay Demirci‐Duarte, Sevtap Arikan‐Akdagli, Demirci-Duarte, Selay   +5 more
core   +1 more source

Effect of Potassium on Saccharomyces cerevisiae Resistance to Fluconazole [PDF]

Antimicrobial Agents and Chemotherapy, 2001
ABSTRACT Susceptibility of strain S288c of Saccharomyces cerevisiae to fluconazole was assayed in the presence and absence of KCl. Addition of 150 mM KCl renders the strain more sensitive to the antifungal agent.
Stella, Carlos Alberto, Burgos, Hilda Isabel   +1 more
openaire   +3 more sources

Development and Characterization of Ribes nigrum Extract‐Loaded PLGA/Chitosan Nanoparticles as a Vaginal Drug Delivery System for Vulvovaginal Candidiasis

Journal of Applied Polymer Science, EarlyView.
Ribes nigrum extract‐loaded PLGA/chitosan nanoparticles is developed as a vaginal drug delivery system for vulvovaginal candidiasis. The chitosan‐coated nanoparticles exhibit favorable physicochemical properties, strong mucoadhesion, sustained release for up to 2 weeks, excellent biocompatibility, and potent antifungal activity against Candida albicans,
Ayca Aslan Aras, Deniz Uygunoz, Emre Karaduman, Neslihan Merve Eren, Secil Gunay Avci, Mehmet Burcin Piskin, Emek Moroydor Derun   +6 more
wiley   +1 more source

MOLECULAR MECHANISMS OF DRUG RESISTANCE IN CANDIDA ALBICANS: ROLE OF TRANSCRIPTION FACTORS MCM1 AND ADA2 [PDF]

, 2011
Candida albicans is an opportunistic fungal pathogen responsible for localized as well as disseminated infections. C. albicans is the most commonly isolated specie from blood cultures, accounting for over 60% of all Candida isolates. The fungistatic drug
MOGAVERO, SELENE
core  

Use of Clotrimazole in Finfish Aquaculture: Mechanistic Insights, Limitations, and Future Directions for Antifungal Therapy

Animal Research and One Health, EarlyView.
This review critically evaluates clotrimazole as a potential antifungal for finfish aquaculture, highlighting strong mechanistic and in vitro efficacy against aquatic mycoses alongside major gaps in in vivo evidence, toxicokinetics, residue safety, and environmental risk, outlining priorities for responsible therapeutic development and regulatory ...
Arya Sen, Debashri Mondal, Thangapalam Jawahar Abraham   +2 more
wiley   +1 more source

The activity of echinocandins, amphotericin B and voriconazole against fluconazole-susceptible and fluconazole-resistant Brazilian Candida glabrata isolates

Memorias do Instituto Oswaldo Cruz, 2012
The extensive use of azole antifungal agents has promoted the resistance of Candida spp to these drugs. Candida glabrata is a problematic yeast because it presents a high degree of primary or secondary resistance to fluconazole. In Brazil, C.
Débora Alves Nunes Mario, Laura Bedin Denardi, Laíssa Arévalo Bandeira, Milene Silva Antunes, Janio Morais Santurio, Luiz Carlos Severo, Sydney Hartz Alves   +6 more
doaj   +1 more source

Detection of antifungal drug-resistant and ERG11 gene mutations among clinical isolates of Candida species isolated from Khartoum, Sudan. [version 2; peer review: 2 approved, 1 not approved]

F1000Research, 2021
Background: Candida species are one of the most important opportunistic fungal pathogens that cause both superficial and systemic infections, especially in immunocompromised individuals.
Ahmed Osman Mohamed, Malik Suliman Mohamed, Mohamed Abdelrahman Hussain, Ibrahim Fatahalrahman Ahmed   +3 more
doaj   +1 more source

Potent In Vitro Synergism of Fluconazole and Osthole against Fluconazole-Resistant Candida albicans [PDF]

Antimicrobial Agents and Chemotherapy, 2017
ABSTRACT Osthole is a natural coumarin that exhibits wide biological and pharmacological activities such as neuroprotective, osteogenic, immunomodulation, antitumor, and anti-inflammatory effects. In this study, we investigated the antifungal effects of osthole in vitro . A checkerboard microdilution assay
De-Dong, Li, Dong, Chai, Xiao-Wen, Huang, Shao-Xing, Guan, Jiang, Du, Hao-Yu, Zhang, Yan, Sun, Yuan-Ying, Jiang   +7 more
openaire   +2 more sources

A narrow bandgap Schottky heterojunction Fe2N/CeO2 microneedle triggering sonodynamic reactive oxygen species storm for drug‐resistance‐free skin fungal infection

BMEMat, EarlyView.
Inorganic sonosensitizers suffer from inefficient electron‐hole separation, rapid recombination, and wide bandgaps in anti‐fungal applications. We propose MN@Fe2N/CeO2 to directly eliminate fungi without drug resistance. Combining semiconductor CeO2's advantages with Fe2N's high work function and activity enables efficient Schottky heterojunctions ...
Li Wang, Jiayi Yang, Ning Tang, Youbin Zheng, Yichao Hou, Chutong Liu, Lihao Guo, Yingying Liao, Gandong Zhou, Weiwei Wu, Xin Du, Shuxiang Xu, Jie Yin, Miaomiao Yuan   +13 more
wiley   +1 more source