Results 61 to 70 of about 27,453 (182)

Indifferent effect of nonsteroidal anti-inflammatory drugs (NSAIDs) combined with fluconazole against multidrug-resistant Candida auris [PDF]

Current Medical Mycology, 2019
Background and Purpose: Emergence and development of antifungal drug resistance in Candida species constitute a serious concern. Candida auris as an emerging multidrug-resistant fungus is the most important public health threat with high levels of ...
Fatemeh Ahangarkani, Sadegh Khodavaisy, Shahram Mahmoudi, Tahereh Shokohi, Mohammad Sadegh Rezai, Hamed Fakhim, Eric Dannaoui, Saharnaz Faraji, Anuradha Chowdhary, Jacques F. Meis, Hamid Badali   +10 more
doaj   +1 more source

The assessment of therapeutic response of oropharyngeal and oesophageal candidiasis in AIDS using a new scoring system: studies with D0870. [PDF]

, 1999
We developed and compared five scoring systems designed to quantitate therapeutic response in cases of oropharyngeal candidiasis. We utilized prospectively collected data on 114 patients treated with several doses of the azole D0870.
Williams, Keith, Denning, David W; id_orcid, Percy, Meryl, Atkinson, Gill, Denning, David W., Hollis, Sally, Hood, Stephen V, Hood, Stephen V.   +7 more
core  

Fluconazole exposure rather than clonal spreading is correlated with the emergence of Candida glabrata with cross-resistance to triazole antifungal agents

, 2014
The emergence of antifungal resistance in Candida species has raised concern in recent years, especially resistance toward triazole. Several newer triazole antifungal agents have been introduced which have a broader spectrum for fungal infections, such ...
陳宜君, Chen, Tun-Chieh;Chen, Yen-Hsu;Chen, Yee-Chun;Lu, Po-Liang   +1 more
core   +1 more source

Clonal Spread of Candida glabrata Bloodstream Isolates and Fluconazole Resistance Affected by Prolonged Exposure: a 12-Year Single-Center Study in Belgium.

, 2018
<p>is a major cause of candidemia in immunocompromised patients and is characterized by a high-level of fluconazole resistance. In the present study, the acquisition of antifungal resistance and potential clonal spread of were explored at a single ...
K. Lagrou, Spriet, Isabel, Isabel Spriet, P. Becker, Berdieke Goemaere, Marijke Hendrickx, Pierre Becker, Lagrou, Katrien, Hendrickx, Marijke, M. Hendrickx, Goemaere, Berdieke, Becker, Pierre, I. Spriet, Katrien Lagrou, B. Goemaere   +14 more
core   +1 more source

Exposure of Cryptococcus neoformans to Seven Commonly Used Agricultural Azole Fungicides Induces Resistance to Fluconazole as Well as Cross-Resistance to Voriconazole, Posaconazole, Itraconazole and Isavuconazole

Pathogens, 2023
Background: Cross-resistance to medical azoles by exposure to azole pesticides is well documented for Aspergillus family fungi but is poorly evaluated for other environmental pathogen fungi, particularly for yeasts belonging to the Cryptococcus ...
Pascal Drakulovski, Donika Krasteva, Virginie Bellet, Sylvie Randazzo, Frédéric Roger, Cyrille Pottier, Sébastien Bertout   +6 more
doaj   +1 more source

A Mechanism Study on the Synergistic Effects of Rifapentine and Fluconazole Against Fluconazole-Resistant Candida Albicans in Vitro

Heliyon, 2023
Candida albicans (C. albicans) is one of the most common clinical isolates of systemic fungal infection. Long-term and inappropriate use of antifungal drugs can cause fungal resistance, which poses a great challenge to the clinical treatment of fungal infections.
Yulian Wang, Yufei He, Tongkai Cai, Zhongwei Lei, Wenzhi Lei, Yongbing Cao, Jianhua Wu   +6 more
openaire   +3 more sources

Phenotypic and genomic characterization of azole resistance in Portuguese Candida parapsilosis isolates

Frontiers in Fungal Biology
IntroductionCandida parapsilosis is a clinically important etiological agent of systemic infections associated with hospital outbreaks, which prevalence has been increasing in the last decade.
Alexandru-Marian Papuc, Cristina Veríssimo, Helena Simões, Cristina Toscano, João Paulo Gomes, João Paulo Gomes, Verónica Mixão, Raquel Sabino, Raquel Sabino, Raquel Sabino   +9 more
doaj   +1 more source

Jjj1 Is a Negative Regulator of Pdr1-Mediated Fluconazole Resistance in Candida glabrata

mSphere, 2018
The high prevalence of fluconazole resistance among clinical isolates of Candida glabrata has greatly hampered the utility of fluconazole for the treatment of invasive candidiasis.
Sarah G. Whaley, Kelly E. Caudle, Lucia Simonicova, Qing Zhang, W. Scott Moye-Rowley, P. David Rogers   +5 more
doaj   +1 more source

The trend of susceptibilities to amphotericin B and fluconazole of Candida species from 1999 to 2002 in Taiwan

BMC Infectious Diseases, 2005
Background Candida species have various degrees of susceptibility to common antifungal drugs. The extent of resistance to amphotericin B and fluconazole of Candida glabrata isolates causing candidemia has been reported. Active surveillance may help us to
Cheng Hsiao-Hsu, Li Shu-Ying, Yang Yun-Liang, Lo Hsiu-Jung   +3 more
doaj   +1 more source

Flucytosine-fluconazole cross-resistance in purine-cytosine permease-deficient Candida lusitaniae clinical isolates: indirect evidence of a fluconazole uptake transporter

, 2003
An unusual interaction between flucytosine and fluconazole was observed when a collection of 60 Candida lusitaniae clinical isolates was screened for cross-resistance.
Noël, Thierry, Paumard, Patrick, Villard, Jean, Chastin, Christiane, François, Fabienne, Brèthes, Daniel   +5 more
core   +1 more source