Results 81 to 90 of about 27,610 (210)

A Mechanism Study on the Synergistic Effects of Rifapentine and Fluconazole Against Fluconazole-Resistant Candida Albicans in Vitro

Heliyon, 2023
Candida albicans (C. albicans) is one of the most common clinical isolates of systemic fungal infection. Long-term and inappropriate use of antifungal drugs can cause fungal resistance, which poses a great challenge to the clinical treatment of fungal infections.
Yulian Wang, Yufei He, Tongkai Cai, Zhongwei Lei, Wenzhi Lei, Yongbing Cao, Jianhua Wu   +6 more
openaire   +3 more sources

Phenotypic and genomic characterization of azole resistance in Portuguese Candida parapsilosis isolates

Frontiers in Fungal Biology
IntroductionCandida parapsilosis is a clinically important etiological agent of systemic infections associated with hospital outbreaks, which prevalence has been increasing in the last decade.
Alexandru-Marian Papuc, Cristina Veríssimo, Helena Simões, Cristina Toscano, João Paulo Gomes, João Paulo Gomes, Verónica Mixão, Raquel Sabino, Raquel Sabino, Raquel Sabino   +9 more
doaj   +1 more source

Emergence of Trichophyton indotineae in Switzerland (2014–2025): Clinical analysis and antifungal susceptibility

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Background and objectives Trichophyton indotineae is an emerging dermatophyte associated with chronic, recalcitrant dermatophytosis and terbinafine resistance due to squalene epoxidase (SQLE) mutations. We analyzed clinical characteristics, antifungal susceptibility profiles, SQLE mutations, and treatment outcomes of cases diagnosed in ...
Annabel H. Lechner, Dennis D. Arnold, Philipp P. Bosshard   +2 more
wiley   +1 more source

Consensus‐based Guideline on tinea capitis

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary The consensus‐based guideline developed under the auspices of the German Dermatological Society (DDG) is intended to provide physicians with a structured framework for clinical decision‐making in the management of patients with tinea capitis and to contribute to improved diagnostic accuracy, treatment adherence, and prevention. Tinea capitis is
Peter Mayser, Dietrich Abeck, Philipp P. Bosshard, Jochen Brasch, Georg Daeschlein, Isaak Effendy, Yvonne Gräser, Peter Höger, Julia Huynh, Maria Kinberger, Annette Kolb‐Mäurer, Katharina Antonia Langen, Bartosz Malisiewicz, Alexander Nast, Hagen Ott, Christin Pelzer, Dieter Reinel, Martin Schaller, Silke Uhrlaß, Pietro Nenoff   +19 more
wiley   +1 more source

Characteristics of Candida isolates from patients with diabetes mellitus. [PDF]

, 2006
The present research has investigated the molecular characterization of oral yeasts in healthy individuals from different dental clinical settings in the United Kingdom, and patients from the UK and Italy who were affected by diabetes mellitus (DM) to ...
Manfredi, M.
core  

Jjj1 Is a Negative Regulator of Pdr1-Mediated Fluconazole Resistance in Candida glabrata

mSphere, 2018
The high prevalence of fluconazole resistance among clinical isolates of Candida glabrata has greatly hampered the utility of fluconazole for the treatment of invasive candidiasis.
Sarah G. Whaley, Kelly E. Caudle, Lucia Simonicova, Qing Zhang, W. Scott Moye-Rowley, P. David Rogers   +5 more
doaj   +1 more source

Deep and disseminated dermatophytosis in immunocompromised populations—A systematic review

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Dermatophyte infections of the dermis and subcutaneous tissue (i.e. deep dermatophytosis)—associated with secondary complications including pseudomycetoma and systemic dissemination—affect vulnerable populations with primary or acquired immunodeficiencies.
Aditya K. Gupta, Tong Wang, Susmita, Ditte Marie L. Saunte, Roderick Hay, Vincent Piguet   +5 more
wiley   +1 more source

The trend of susceptibilities to amphotericin B and fluconazole of Candida species from 1999 to 2002 in Taiwan

BMC Infectious Diseases, 2005
Background Candida species have various degrees of susceptibility to common antifungal drugs. The extent of resistance to amphotericin B and fluconazole of Candida glabrata isolates causing candidemia has been reported. Active surveillance may help us to
Cheng Hsiao-Hsu, Li Shu-Ying, Yang Yun-Liang, Lo Hsiu-Jung   +3 more
doaj   +1 more source

Practical recommendations for seborrheic dermatitis management: An expert consensus

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This modified Delphi study established expert consensus on Seborrheic Dermatitis management. Key findings prioritize combined topical antifungal and anti‐inflammatory therapy for both acute flares and long‐term maintenance. The consensus also provides a clear framework for escalating to systemic treatment in extensive or refractory cases.
L. Naldi, A. Kyrgidis, G. S. Tiplica, M. A. de Rie, D. Tatsis, P. Gisondi, D. Ioannides, O. Chosidow, M. Deleuran, the Delphi SD study experts   +9 more
wiley   +1 more source

Platelet‐Rich Fibrins as Local Drug‐Delivery Carriers

Journal of Periodontal Research, EarlyView.
Autologous platelet concentrates (APCs), particularly platelet‐rich fibrin (PRF), act as biologically active fibrin scaffolds, capable of entrapping and gradually releasing therapeutic agents in oral and periodontal therapy. The incorporation of bioactive compounds, such as antibiotics, antifungals, vitamins, antidiabetic drugs, and exosomes, enhances ...
Karim M. Fawzy El‐Sayed, Christof E. Dörfer   +1 more
wiley   +1 more source