Results 11 to 20 of about 41,055 (201)
Di-san junyi daxue xuebao, 2020 Objective To screen the genes associated with fluconazole resistance in Trichosporon asahii to facilitate mechanistic studies of fluconazole resistance and the development of new antifungal agents. Methods Three clinical isolates of fluconazole-sensitive
XIA Zhikuan1 +6 more
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Fluconazole resistance in Candida species: a current perspective
Infection and Drug Resistance, 2017 Elizabeth L Berkow, Shawn R Lockhart Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA Abstract: Candida albicans and the emerging non-albicans Candida spp.
Berkow EL, Lockhart SR
doaj +3 more sources
Frontiers in Cellular and Infection MicrobiologyCandida auris has emerged as a critical nosocomial pathogen that particularly affects immunocompromised and critically ill patients in intensive care units, and it is associated with high mortality.
Ji-Hui Bae, Yong-Bin Eom, Yong-Bin Eom
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Genomic Variation-Mediating Fluconazole Resistance in Yeast. [PDF]
Biomolecules, 2022 Fungal infections pose a serious and growing threat to public health. These infections can be treated with antifungal drugs by killing hazardous fungi in the body. However, the resistance can develop over time when fungi are exposed to antifungal drugs by generating genomic variations, including mutation, aneuploidy, and loss of heterozygosity.
Wang WY +7 more
europepmc +4 more sources
Ibuprofen-Mediated Reversal of Fluconazole Resistance in Clinical Isolates of Candida [PDF]
Journal of Clinical and Diagnostic Research, 2015 Introduction: In view of the increasing prevalence of invasive Candidiasis in today’s health-care scenario and the emergence of fluconazole resistance among clinical isolates of Candida, we sought to determine if Ibuprofen could elicit a reversal of ...
Monika Sharma +6 more
doaj +1 more source
Fluconazole resistance in Candida glabrata [PDF]
Antimicrobial Agents and Chemotherapy, 1993 We report a case of infection with Candida glabrata in which the organism became resistant to fluconazole and in which pre- and posttreatment isolates were available for comparison. The organism was cross-resistant to ketoconazole and itraconazole, in common with other azole-resistant yeasts.
C A, Hitchcock +4 more
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Fluconazole Assists Berberine To Kill Fluconazole-Resistant Candida albicans [PDF]
Antimicrobial Agents and Chemotherapy, 2013 ABSTRACT It was found in our previous study that berberine (BBR) and fluconazole (FLC) used concomitantly exhibited a synergism against FLC-resistant Candida albicans in vitro . The aim of the present study was to clarify how BBR and FLC worked synergistically and the underlying mechanism ...
De-Dong, Li +10 more
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Mutations in
mBio, 2020 Candida auris has emerged as a multidrug-resistant pathogen of great clinical concern. Approximately 90% of clinical C. auris isolates are resistant to fluconazole, the most commonly prescribed antifungal agent, and yet it remains unknown what mechanisms
Jeffrey M. Rybak +12 more
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Journal of Global Antimicrobial Resistance, 2020 Introduction: Fluconazole resistance in Candida tropicalis health care–associated infections is increasing. We investigated the role of efflux pump and mutations in ERG11p conferring fluconazole resistance in C. tropicalis. Materials and methods: A total
Nidhi Pandey +3 more
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Risk Factors for Fluconazole-Resistant Candidemia [PDF]
Antimicrobial Agents and Chemotherapy, 2010 ABSTRACT Previous studies have sought to determine the risk factors associated with candidemia caused by non- albicans Candida spp. or with potentially fluconazole-resistant Candida spp. ( C. glabrata and C. krusei ).
José, Garnacho-Montero +7 more
openaire +2 more sources