Results 101 to 110 of about 605,588 (181)

Loss of Upc2p-Inducible ERG3 Transcription Is Sufficient To Confer Niche-Specific Azole Resistance without Compromising Candida albicans Pathogenicity

mBio, 2018
Inactivation of sterol Δ5,6-desaturase (Erg3p) in the prevalent fungal pathogen Candida albicans is one of several mechanisms that can confer resistance to the azole antifungal drugs.
Arturo Luna-Tapia, Hubertine M. E. Willems, Josie E. Parker, Hélène Tournu, Katherine S. Barker, Andrew T. Nishimoto, P. David Rogers, Steven L. Kelly, Brian M. Peters, Glen E. Palmer   +9 more
doaj   +1 more source

tolerance: An R Package for Estimating Tolerance Intervals [PDF]

The tolerance package for R provides a set of functions for estimating and plotting tolerance limits. This package provides a wide-range of functions for estimating discrete and continuous tolerance intervals as well as for estimating regression ...
Derek S. Young
core  

Fluconazole resistance in Candida species: a current perspective

, 2017
Elizabeth L Berkow, Shawn R Lockhart Mycotic Diseases Branch, Centers for Disease Control and Prevention, Atlanta, GA, USA Abstract: Candida albicans and the emerging non-albicans Candida spp.
Lockhart SR, Berkow EL
core  

Characteristics of Candida isolates from patients with diabetes mellitus. [PDF]

, 2006
The present research has investigated the molecular characterization of oral yeasts in healthy individuals from different dental clinical settings in the United Kingdom, and patients from the UK and Italy who were affected by diabetes mellitus (DM) to ...
Manfredi, M.
core  

The Neosartorya (Aspergillus) fischeri antifungal protein NFAP2 has low potential to trigger resistance development in Candida albicans in vitro

Microbiology Spectrum
Due to the increase in the number of drug-resistant Candida albicans strains, new antifungal compounds with limited potential for the development of resistance are urgently needed.
Gábor Bende, Nóra Zsindely, Krisztián Laczi, Zsolt Kristóffy, Csaba Papp, Attila Farkas, Liliána Tóth, Szabolcs Sáringer, László Bodai, Gábor Rákhely, Florentine Marx, László Galgóczy   +11 more
doaj   +1 more source

Sterol‐Targeted Laboratory Evolution Allows the Isolation of Thermotolerant and Respiratory‐Competent Clones of the Industrial Yeast Saccharomyces cerevisiae

Microbial Biotechnology
Sterol composition plays a crucial role in determining the ability of yeast cells to withstand high temperatures, an essential trait in biotechnology.
Isabel‐Elena Sánchez‐Adriá, Jose A. Prieto, Gemma Sanmartín, Miguel Morard, Estéfani García‐Ríos, Francisco Estruch, Francisca Randez‐Gil   +6 more
doaj   +1 more source

Fluconazole-resistant oral candidosis in a repeatedly treated female AIDS patient. [PDF]

, 1994
Bogner, Johannes R., Eva Thoma‐Greber, H. C. Korting, Goebel, Frank-Detlef, Korting, H. C., Thoma-Greber, E., F.‐D. Goebel, J. Bogner   +7 more
core   +1 more source

The zinc cluster transcription factor Znc1 regulates Rta3-dependent miltefosine resistance in Candida albicans

mSphere
Zinc cluster transcription factors (ZCFs) are a family of transcription regulators that are almost exclusively found in the fungal kingdom. Activating mutations in the ZCFs Mrr1, Tac1, and Upc2 frequently cause acquired resistance to the widely used ...
Bernardo Ramírez-Zavala, Ines Krüger, Sonja Schwanfelder, Katherine S. Barker, P. David Rogers, Joachim Morschhäuser   +5 more
doaj   +1 more source

Tolerance

, 2016
Tolerance ...
Holeski, Liza, Liza Holeski (3257763), Kruger, Eric, Rubert-Nason, Kennedy, Eric Kruger (433685), Lindroth, Richard, Couture, John, Sean McKenzie (3257757), Richard Lindroth (3257760), McKenzie, Sean, Kennedy Rubert-Nason (3257754), John Couture (433683)   +11 more
core   +1 more source

Identification and characterization of mediators of fluconazole tolerance in Candida albicans

, 2019
Candida spp. are major human pathogens and a major issue in intensive care units around the world. Candida infections have a high mortality rate despite the use of antifungal treatments. One cause of these therapeutic failures is the acquisition of mutations in the fungus leading to antifungal resistance.
openaire   +1 more source