Results 91 to 100 of about 5,860 (175)

Successive applications of Antimicrobial Photodynamic Therapy effects the susceptibility of Candida albicans grown in medium with or without fluconazole

, 2020
Antimicrobial Photodynamic Therapy (aPDT) was introduced as a therapy due to resistance that microorganisms have developed to conventional drugs. The study aimed to evaluate the potential of successive applications of aPDT in effecting Candida albicans ...
Carmello, Juliana Cabrini [UNESP], Jordão, Cláudia Carolina [UNESP], Pavarina, Ana Cláudia [UNESP], Klein, Marlise Inêz [UNESP], Dias, Luana Mendonça [UNESP], Bellini, Amanda [UNESP]   +5 more
core   +1 more source

Progrès récents de la thérapeutique antifongique: intérêt du fluconazole.

, 1990
Invasive fungal infections are major problems in immunocompromised patients and optimal therapeutical modalities are still far from optimal. Recently, progresses of antifungal therapy have been achieved with the development of new antifungal agents.
Meunier, Françoise
core  

The Neosartorya (Aspergillus) fischeri antifungal protein NFAP2 has low potential to trigger resistance development in Candida albicans in vitro

Microbiology Spectrum
Due to the increase in the number of drug-resistant Candida albicans strains, new antifungal compounds with limited potential for the development of resistance are urgently needed.
Gábor Bende, Nóra Zsindely, Krisztián Laczi, Zsolt Kristóffy, Csaba Papp, Attila Farkas, Liliána Tóth, Szabolcs Sáringer, László Bodai, Gábor Rákhely, Florentine Marx, László Galgóczy   +11 more
doaj   +1 more source

C. albicans functional genomic screen identifies novel genetic circuitry important for azole tolerance and resistance.

, 2018
A) Schematic of functional genomic screen to identify genes important for fluconazole (FL) tolerance. Thirteen genes were identified and prioritized for follow-up analysis based on the robust hypersensitivity of the corresponding deletion mutants. B) The
Nicole Robbins (206417), Leah E. Cowen (108693), Nicole M. Revie (5150279), Anna Selmecki (38074), Robert T. Todd (5150282), Michael Costanzo (178059), Harley O’Connor Mount (5150273), Charles Boone (21213), Kaitlin Anstett (5150276), Cathy Collins (60217)   +9 more
core   +1 more source

Tolerance to the antifungal drug fluconazole is mediated by tuning cytoplasmic fluidity

Abstract Treatment failure rates for fungal infections cannot be explained simply by increased rates of drug resistance. Antifungal drug tolerance, the ability of a susceptible isolate to grow in the presence of inhibitory drug concentrations, relies upon a broad set of stress response pathways and can contribute to antifungal drug ...
E. Plumb, A. Serrano, L. Chevalier, J. Elferich, L.R. Sinn, N. Grigorieff, M. Ralser, J. Berman, M. Bassilana, R.A. Arkowitz   +9 more
openaire   +1 more source

Image_2_Machine Learning Approach for Candida albicans Fluconazole Resistance Detection Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry.pdf

, 2020
Candida albicans causes life-threatening systemic infections in immunosuppressed patients. These infections are commonly treated with fluconazole, an antifungal agent targeting the ergosterol biosynthesis pathway.
Margot Delavy (8294664), Dominique Sanglard (189012), Guy Prod’hom (8294667), Lorenzo Cerutti (13957), Alix T. Coste (8294670), Antony Croxatto (248153), Gilbert Greub (39465)   +6 more
core   +1 more source

Data_Sheet_1_Machine Learning Approach for Candida albicans Fluconazole Resistance Detection Using Matrix-Assisted Laser Desorption/Ionization Time-of-Flight Mass Spectrometry.docx

, 2020
Candida albicans causes life-threatening systemic infections in immunosuppressed patients. These infections are commonly treated with fluconazole, an antifungal agent targeting the ergosterol biosynthesis pathway.
Margot Delavy (8294664), Dominique Sanglard (189012), Guy Prod’hom (8294667), Lorenzo Cerutti (13957), Alix T. Coste (8294670), Antony Croxatto (248153), Gilbert Greub (39465)   +6 more
core   +1 more source

Sterol‐Targeted Laboratory Evolution Allows the Isolation of Thermotolerant and Respiratory‐Competent Clones of the Industrial Yeast Saccharomyces cerevisiae

Microbial Biotechnology
Sterol composition plays a crucial role in determining the ability of yeast cells to withstand high temperatures, an essential trait in biotechnology.
Isabel‐Elena Sánchez‐Adriá, Jose A. Prieto, Gemma Sanmartín, Miguel Morard, Estéfani García‐Ríos, Francisco Estruch, Francisca Randez‐Gil   +6 more
doaj   +1 more source

Inhibition of Vesicular Transport Influences Fungal Susceptibility to Fluconazole

, 2019
Fungal infections pose a substantial threat to the human population. They can cause either mild and relatively harmless infections or invasive and often lethal diseases in patients with a weakened immune system.
Demuyser, Liesbeth, Timmermans, Bea, Van Dijck, Patrick, Van Dyck, Katrien   +3 more
core   +1 more source

Poster Sessions

HemaSphere, Volume 10, Issue S1, June 2026.
wiley   +1 more source