Automated Synthesis of [18F]Flumazenil Application in GABAA Receptor Neuroimaging Availability for Rat Model of Anxiety [PDF]
Pharmaceuticals, 2023 Clinical studies have demonstrated that the γ-aminobutyric acid type A (GABAA) receptor complex plays a central role in the modulation of anxiety.
Shiou-Shiow Farn +5 more
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GABAA receptor availability relates to emotion-induced BOLD responses in the medial prefrontal cortex: simultaneous fMRI/PET with [11C]flumazenil [PDF]
Frontiers in Neuroscience, 2023 IntroductionThe fMRI BOLD response to emotional stimuli highlighting the role of the medial prefrontal cortex (MPFC) has been thoroughly investigated.
Alexander Heinzel +17 more
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Re-sedation using remimazolam anesthesia in patients with multiple injuries during recovery: a case report and literature review [PDF]
Frontiers in MedicineRemimazolam combined with flumazenil can shorten recovery time, but the occurrence of re-sedation may put the patient at risk. Herein, we report a case of a 50-year-old woman who underwent general anesthesia using remimazolam.
Guozun He, Chuangguo Shi, Wei Gao
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Effect of flumazenil on recovery of memory following recovery of consciousness from general anesthesia with remimazolam: a randomized, open-label, single-center controlled trial [PDF]
JA Clinical ReportsBackground Recovery of consciousness from general anesthesia with remimazolam, an ultrashort-acting benzodiazepine, occurs rapidly. However, patients after recovery of consciousness from general anesthesia with remimazolam often experience periods of ...
Keiko Nobukuni +8 more
doaj +2 more sources
Clinical enigma: Case-based systematic review of flumazenil in the management of paradoxical reactions to midazolam – A quarter-century perspective [PDF]
Journal of Anaesthesiology Clinical PharmacologyBackground and Aims: The mechanism of paradoxical reaction is still a big question for the medical world, but several theoretical approaches have arisen. Midazolam, a high-potency benzodiazepine, carries a higher risk of paradoxical reaction. Paradoxical
Nabilah P. Utami +4 more
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Addiction of High Dose of Benzodiazepine: Verona Detox Approach With Flumazenil
Frontiers in Psychiatry, 2022 IntroductionSince the 1990s there has been evidence of the significant role Flumazenil (FLU) has in benzodiazepines (BZD) detoxes. The Verona Detox approach has been developed for high dose BZD and Z-drug detoxification via continuous subcutaneous ...
Rebecca Casari +6 more
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Antagonistic effect of flumazenil on tiletamine-zolazepam-induced anaesthesia in Beagle dogs [PDF]
Veterinární Medicína, 2018 Benzodiazepines exert hypnotic/sedative effects through their inhibitory actions on the γ-aminobutyric acid receptor type A. Since flumazenil antagonises these effects through competitive inhibition of the receptor, it has been used to reverse the effect
J.Y. Lee +4 more
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Efecto antagonista del flumazenil sobre el isoflurano en la emersión de la anestesia general [PDF]
Revista Chilena de Anestesia, 2020 Javier Eduardo Moreno Sánchez +2 more
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The neurobehavioral effects of flumazenil in chicks [PDF]
Iraqi Journal of Veterinary Sciences, 2021 Flumazenil is choosy and competitive GABA receptor blocker that serves as an antidote to benzodiazepines overdose. Its administration in humans and some animal’s model is connected with nervousness, anxiety responses, or seizures attacks.
Ahmed S. Naser, Yasser M. Albadrany
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Comparison of Remimazolam and Midazolam for Sedation During Endoscopic Retrograde Cholangiopancreatography-Related Procedures. [PDF]
DEN OpenABSTRACT Objectives Remimazolam is an ultra‐short‐acting benzodiazepine recently approved for endoscopic procedures in Japan as a sedative agent. We aimed to compare the efficacy and safety of remimazolam and midazolam for endoscopic retrograde cholangiopancreatography (ERCP)‐related procedures.
Tanisaka Y +7 more
europepmc +2 more sources