Results 31 to 40 of about 7,804 (196)

Efficacy and safety of remimazolam tosilate versus propofol in patients undergoing day surgery: a prospective randomized controlled trial

BMC Anesthesiology, 2023
Background Remimazolam tosilate (RT) is a novel short-acting GABA (A) receptor agonist that has a rapid recovery from procedural sedation and can be fully reversed by flumazenil.
Wenchen Luo, Minli Sun, Jie Wan, Zhenyu Zhang, Jian Huang, Jinlin Zhang, Wanxia Xiong, Lirong Xia, Peiyao Xu, Changhong Miao, Xuesong Zhang, Mingyue Liu, Jing Zhong   +12 more
doaj   +1 more source

Re-audit of the use of flumazenil following midazolam-induced conscious sedation

BDJ Open, 2023
Introduction Flumazenil is an antagonist drug of Benzodiazepam (BDZ) that has been used as a reversal agent of midazolam-induced conscious sedation (CS) in both emergency and elective procedures.
Muhammad Syafiq Asyraf Rosli, Ellie Heidari   +1 more
doaj   +1 more source

Flumazenil, a Benzodiazepine Receptor Anatagonist, in the Reversal of Conscious Sedation following Gastroscopy. A Placebo Controlled, Dose Finding Study

Canadian Journal of Gastroenterology, 1991
Tim double-blind, placebo controlled, study assessed the efficacy and safety of flumazenil, a benzodiazepine antagonist, in reversing diazepam-induced sedation in 60 patients undergoing endoscopy.
Lloyd Sutherland, Noel Hershfield, Eldon Shaffer, Lorne Price, Deanne Dean, Margaret Light   +5 more
doaj   +1 more source

Long-term delayed emergence after remimazolam-based general anesthesia: a case report

JA Clinical Reports, 2022
Background Remimazolam is an ultra-short-acting benzodiazepine anesthetic that is antagonized by flumazenil, and it is typically expected to be applied in anesthesia with the purpose of ensuring early postoperative recovery. We report a case of long-term
Tsubasa Takemori, Yoshimasa Oyama, Takenori Makino, Seigo Hidaka, Takaaki Kitano   +4 more
doaj   +1 more source

Could Flumazenil Be Used Pre-hospital by Intramuscular Injection for Coma due to Mixed Drug Overdose Not Responding to Naloxone?: A Systematic Review of the Evidence. [PDF]

Basic Clin Pharmacol Toxicol
Farcas I, Schölin L, Eddleston M.
europepmc   +3 more sources

Bolus infusion scheme for the adjustment of steady state [11C]Flumazenil levels in the grey matter and in the blood plasma for neuroreceptor imaging

NeuroImage, 2020
The use of hybrid PET/MR imaging facilitates the simultaneous investigation of challenge-related changes in ligand binding to neuroreceptors using PET, while concurrently measuring neuroactivation or blood flow with MRI. Having attained a steady state of
Jörg Mauler, Alexander Heinzel, Andreas Matusch, Hans Herzog, Irene Neuner, Jürgen Scheins, Christine Wyss, Jürgen Dammers, Markus Lang, Johannes Ermert, Bernd Neumaier, Karl-Josef Langen, N. Jon Shah   +12 more
doaj   +1 more source

Comparison of postoperative nausea and vomiting between remimazolam and propofol: a propensity score-matched, retrospective, observational, single-center cohort study [PDF]

Korean Journal of Anesthesiology, 2023
Background Remimazolam is a novel ultrashort-acting benzodiazepine that has recently become available for general anesthesia. However, the incidence of postoperative nausea and vomiting (PONV) associated with remimazolam remains unknown.
Yuji Suzuki, Shingo Kawashima, Hiroshi Makino, Matsuyuki Doi, Yoshiki Nakajima   +4 more
doaj   +1 more source

[11C]flumazenil binding is increased in a dose-dependent manner with tiagabine-induced elevations in GABA levels. [PDF]

PLoS ONE, 2012
Evidence indicates that synchronization of cortical activity at gamma-band frequencies, mediated through GABA-A receptors, is important for perceptual/cognitive processes.
W Gordon Frankle, Raymond Y Cho, N Scott Mason, Chi-Min Chen, Michael Himes, Christopher Walker, David A Lewis, Chester A Mathis, Rajesh Narendran   +8 more
doaj   +1 more source

Long-Term Management of Generalised Anxiety Disorder with Low-Dose Continuous Infusions of Flumazenil: A Case Series

Behavioral Sciences, 2022
Background: Generalised anxiety disorder (GAD) is a common anxiety disorder associated with social and occupational impairment. Recently, a theory was postulated that dysfunctional gamma aminobutyric acid type A receptors (GABAA) are implicated in ...
Alexander T. Gallo, Stephen Addis, Vlad Martyn, Hishani Ramanathan, Grace K. Wilkerson, Sean D. Hood, Hans Stampfer, Gary K. Hulse   +7 more
doaj   +1 more source

Redox‐aktivierte Sonden für Hochkontrastige Live‐Bildgebung Postsynaptischer Neuronaler Gerüste

Angewandte Chemie, EarlyView.
Sylives sind modifizierte fluoreszierende Peptide für eine kontrastreiche Live‐Bildgebung inhibitorischer (Gephyrin) und exzitatorischer (PSD‐95) postsynaptischer Gerüststrukturen in nativen Neuronen. Eine saubere Markierung erfordert niedrige Sondenkonzentrationen im Nanomolarbereich, während die Aufnahme mikromolare Konzentrationen zellpenetrierender
Christiane Huhn, Clémence Mille, Sheng‐Yang Ho, Felix Lützenkirchen, Vladimir Khayenko, Melanie Hein, Christian Werner, Matthias Kneussel, Johannes W. Hell, Christian G. Specht, Hans M. Maric   +10 more
wiley   +1 more source