Antagonistic effect of flumazenil on tiletamine-zolazepam-induced anaesthesia in Beagle dogs
Veterinární Medicína, 2018 Benzodiazepines exert hypnotic/sedative effects through their inhibitory actions on the γ-aminobutyric acid receptor type A. Since flumazenil antagonises these effects through competitive inhibition of the receptor, it has been used to reverse the effect
J.Y. Lee +4 more
doaj +1 more source
In Vivo Measurement of Hippocampal GABAA/cBZR Density with [18F]-Flumazenil PET for the Study of Disease Progression in an Animal Model of Temporal Lobe Epilepsy [PDF]
, 2014 PURPOSE: Imbalance of inhibitory GABAergic neurotransmission has been proposed to play a role in the pathogenesis of temporal lobe epilepsy (TLE).
Berard, A +11 more
core +2 more sources
Midazolam use for dental conscious sedation: how safe are we? [PDF]
, 2018 Aim: To explore the safety awareness of midazolam use amongst dentist in the UK. Materials and methods: A cross-sectional study on 203 dentists was undertaken, 146 of whom currently practice conscious sedation using intravenous midazolam.
Flood, C +5 more
core +2 more sources
Evaluation of butorphanol, medetomidine and midazolam as a reversible narcotic combination in free-ranging African lions (Panthera leo) [PDF]
, 2010 Objective To evaluate the effects of the combination butorphanol, medetomidine and midazolam (BMM) and its reversibility in lions. Study design Prospective clinical trial.
Bush +37 more
core +1 more source
GABA deficiency in NF1: a multimodal [11C]-Flumazenil and spectroscopy study [PDF]
, 2016 Objective: To provide a comprehensive investigation of the GABA system in patients with Neurofibromatosis type 1 (NF1) that allows understanding the nature of the GABA imbalance in humans at pre- and post-synaptic levels. Methods: In this cross-sectional
Abrunhosa, AJ +6 more
core +1 more source
PHARMACOKINETICS OF FLUMAZENIL AND MIDAZOLAM
British Journal of Anaesthesia, 1993 We have studied simultaneously the pharmacokinetics of flumazenil and midazolam in 12 healthy Chinese children, aged 5-9 yr, undergoing circumcision. Two hours before operation each patient received midazolam 0.5 mg kg-1 orally for premedication and 0.5 mg kg-1 i.v. during induction.
I. D. Smith +5 more
openaire +3 more sources
Molecules, 2020 Anxiety is a chronic severe psychiatric disorder. Crocins are among the various bioactive components of the plant Crocus sativus L. (Iridaceae) and their implication in anxiety is well-documented.
Nikolaos Pitsikas, Petros A. Tarantilis
doaj +1 more source
Risperidone in a child with untractable emergency delirium: a case report [PDF]
Korean Journal of Anesthesiology, 2016 A 6-year-old boy was scheduled for thoracic magnetic resonance imaging under deep sedation with midazolam 1.8 mg and propofol 100 µg/kg/min via intravenous injection. He showed emergence delirium in the post-anesthesia care unit.
Young Hee Shin +2 more
doaj +1 more source
In vivo Illustration of Altered Dopaminergic and GABAergic Systems in Early Parkinson's Disease
Frontiers in Neurology, 2022 BackgroundChanges in γ-aminobutyric acid (GABA) function are noted in patients with Parkinson's disease (PD) who have some non-motor impairments. However, dopamine-related GABA function and GABA-related cognitive changes are still unclear.MethodsThirteen
Hirotsugu Takashima +9 more
doaj +1 more source
Reducing risk of overdose with midazolam injection in adults: an evaluation of change in clinical practice to improve patient safety in England [PDF]
, 2014 Rationale aims and objectives. This study sought to evaluate potential reductions in risk associated with midazolam injection, a sedating medication, following a United Kingdom National Patient Safety Alert.
Abeysekera1 +15 more
core +2 more sources