Results 61 to 70 of about 14,172 (248)

Addiction of High Dose of Benzodiazepine: Verona Detox Approach With Flumazenil

Frontiers in Psychiatry, 2022
IntroductionSince the 1990s there has been evidence of the significant role Flumazenil (FLU) has in benzodiazepines (BZD) detoxes. The Verona Detox approach has been developed for high dose BZD and Z-drug detoxification via continuous subcutaneous ...
Rebecca Casari, Antonio Metastasio, Lorenzo Zamboni, Lorenzo Zamboni, Martino Biasioli, Simone Campagnari, Fabio Lugoboni   +6 more
doaj   +1 more source

The human photosensitive epilepsy model for clinical proof‐of‐principle trials of novel antiseizure medications: 2. Analysis of drug trials and predictive value of the model

Epilepsia, EarlyView.
Abstract Clinical development of novel antiseizure medications (ASMs) would benefit from an early proof of principle (POP) model. The photosensitivity model, which uses the photoparoxysmal electroencephalographic response (PPR) as a surrogate of seizures, is currently the only human model that allows POP trials of investigational compounds after a ...
Wolfgang Löscher, Dorothée Kasteleijn‐Nolst Trenité   +1 more
wiley   +1 more source

Prolonged infusion of flumazenil for the reversal of sedation from chlordiazepoxide: a case report

Toxicology Communications
A continuous infusion of flumazenil may be needed to mitigate prolonged sedation from benzodiazepines. Some benzodiazepines have extended durations of action.
Anthony Spadaro, Mehruba Parris, Paul Valestra, Howard A. Greller, Diane P. Calello, Lewis S. Nelson, Christopher W. Meaden   +6 more
doaj   +1 more source

The First Satellite Flipper Tag Deployments on Steller Sea Lions Allow Tracking Beyond the Annual Molt

Marine Mammal Science, EarlyView.
ABSTRACT Entanglement in marine debris and fishing gear is increasingly recognized as a serious source of human‐caused mortality for pinniped population world‐wide and has been shown to contribute to Steller sea lion injury and mortality. As such, our primary goal in testing these location‐only satellite flipper tags was to track post‐entanglement ...
Kimberly L. Raum‐Suryan, Lauri A. Jemison, Michael J. Rehberg, Katharine N. Savage   +3 more
wiley   +1 more source

Gamma oscillations in V1 are correlated with GABA(A) receptor density: A multi-modal MEG and Flumazenil-PET study. [PDF]

, 2015
High-frequency oscillations in the gamma-band reflect rhythmic synchronization of spike timing in active neural networks. The modulation of gamma oscillations is a widely established mechanism in a variety of neurobiological processes, yet its ...
Bouet, R., Bouvard, S., Ciumas, C., Jerbi, K., Jung, J., Kujala, J., Lecaignard, F., Lothe, A., Ryvlin, P.   +8 more
core   +2 more sources

Chest wall lift for thoracoscopic lung lobectomy: Technique and results in two cats

Veterinary Surgery, Volume 54, Issue 4, Page 694-704, May 2025.
Abstract Objective To report the technique and outcomes of utilizing chest wall lift to perform thoracoscopic surgery in two cats. Study design Short case series. Animals Client‐owned cats (n = 2). Methods A geriatric cat was referred for pleural effusion secondary to a left cranial lung lobe mass. A thoracoscopic exploration of the left hemithorax was
Adrien Aertsens, Helen Tsoi, Micah Esala, Emily P. Wheeler   +3 more
wiley   +1 more source

Benzodiazepine poisoning in elderly [PDF]

Vojnosanitetski Pregled, 2016
Background/Aim. Benzodiazepines are among the most frequently ingested drugs in self-poisonings. Elderly may be at greater risk compared with younger individuals due to impaired metabolism and increased sensitivity to benzodiazepines. The aim of
Perković-Vukčević Nataša, Vuković-Ercegović Gordana, Šegrt Zoran, Đorđević Snežana, Jović-Stošić Jasmina   +4 more
doaj   +1 more source

Coagulopathy as a Complication of Cardiopulmonary Arrest Following Balloon Valvuloplasty in a Dog

Veterinary Medicine and Science, Volume 11, Issue 4, July 2025.
An 8‐month‐old dog developed a consumptive coagulopathy and presumptive DIC following cardiac arrest during a balloon valvuloplasty procedure. Successful management required massive transfusion therapy and critical care. ABSTRACT Objective To describe successful management of a coagulopathy secondary to cardiopulmonary arrest (CPA) associated with ...
Marissa A. Turner, Theresa C. Hallowell
wiley   +1 more source

Benzodiazepine receptor ligand influences on learning: an endogenous modulatory mechanism mediated by benzodiazepines possibly of alimentary origin

Memorias do Instituto Oswaldo Cruz, 1991
In rats pre-but not post-training ip administration of either flumazenil, a central benzodiazepine (BSD) receptor antagonist, or of n-butyl-B-carboline-carboxylate (BCCB), an inverse agonist, enhanced retention of inhibitory avoidance learning ...
I. Izquierdo, M. E. Pereira, C. da Cunha, C. Wolfman, J. H. Medina   +4 more
doaj   +1 more source

Evaluation of the Sleep-Prolonging Effect of Lagenaria vulgaris and Cucurbita pepo Extracts on Pentobarbital-Induced Sleep and Possible Mechanisms of Action

Medicina, 2018
Introduction: Sleeplessness is the most common sleep disorder. In this study, the hypnotic effect of macerated (HAME) and soxhlet (HASE) extract of Lagenaria vulgaris (fruit and seed) and Cucurbita pepo (fruit) were studied in mice. Methods: Extracts and
Vafa Baradaran Rahimi, Vahid Reza Askari, Amineh Sadat Tajani, Azar Hosseini, Hassan Rakhshandeh   +4 more
doaj   +1 more source