Results 1 to 10 of about 3,310,279 (379)

Synthesis and Evaluation of Fluorine-18-Labeled L-Rhamnose Derivatives [PDF]

Molecules, 2023
The use of radiolabeled glucose for PET imaging resulted in the most commonly used tracer in the clinic, 2-deoxy-2-[18F]fluoroglucose (FDG). More recently, other radiolabeled sugars have been reported for various applications, including imaging tumors ...
Xiang Zhang, Falguni Basuli, Zhen-Dan Shi, Swati Shah, Jianfeng Shi, Amelia Mitchell, Jianhao Lai, Zeping Wang, Dima A. Hammoud, Rolf E. Swenson   +9 more
doaj   +4 more sources

Fluorine-18: Radiochemistry and Target-Specific PET Molecular Probes Design [PDF]

Frontiers in Chemistry, 2022
The positron emission tomography (PET) molecular imaging technology has gained universal value as a critical tool for assessing biological and biochemical processes in living subjects.
Yunze Wang, Yunze Wang, Yunze Wang, Qingyu Lin, Qingyu Lin, Qingyu Lin, Hongcheng Shi, Hongcheng Shi, Hongcheng Shi, Dengfeng Cheng, Dengfeng Cheng, Dengfeng Cheng   +11 more
doaj   +3 more sources

Novel Strategies for Fluorine‐18 Radiochemistry [PDF]

Angewandte Chemie International Edition, 2012
Peer Reviewedhttp://deepblue.lib.umich.edu/bitstream/2027.42/90272/1/1106_ftp ...
Agard, Aigbirhio, Banks, Campbell-Verduyn, Carroll, Ermert, Gail, Glaser, Hollingworth, Lee, Li, Mamat, Meldal, Miller, Pike, Pike, Ross, Scott, Shah, Shiue, Teare, Teare, Telu, Wittig   +23 more
core   +5 more sources

Isotopic Radiolabeling of Crizotinib with Fluorine-18 for In Vivo Pet Imaging [PDF]

Pharmaceuticals, 2022
Crizotinib is a tyrosine kinase inhibitor approved for the treatment of non-small-cell lung cancer, but it is inefficient on brain metastases. Crizotinib is a substrate of the P-glycoprotein, and non-invasive nuclear imaging can be used to assess the ...
Malvika Sardana, Louise Breuil, Sébastien Goutal, Maud Goislard, Mikhail Kondrashov, Etienne Marchal, Florent L. Besson, Christophe Dugave, Gail Wrigley, Anna C. Jonson, Bertrand Kuhnast, Magnus Schou, Nicolas Tournier, Charles S. Elmore, Fabien Caillé   +14 more
doaj   +2 more sources

Development Of Novel Fluorine-18 Labeled Pet Radioligands For Monoamine Oxidase B (Mao-B) [PDF]

, 2013
Monoamine oxidases (MAO-A and MAO-B) are important enzymes regulating the levels of monoaminergic neurotransmitters. Selectiv e and irreversible MAO-B inhibitors such as L -deprenyl and rasagiline are clinically used for the t reatment of ...
Sangram Nag
openalex   +5 more sources

Fluorine-18 Labelled Radioligands for PET Imaging of Cyclooxygenase-2 [PDF]

Molecules, 2022
Molecular imaging probes enable the early and accurate detection of disease-specific biomarkers and facilitate personalized treatment of many chronic diseases, including cancer.
Jatinder Kaur, Atul Bhardwaj, Frank Wuest   +2 more
doaj   +2 more sources

Sultones for Radiofluorination and Bioconjugation: Fluorine-18 Labeling of Native Proteins and Glycoproteins. [PDF]

ACS Omega
Lafargue AE, Maingueneau C, Bernay B, Ejjoummany A, Perrio C.   +4 more
europepmc   +2 more sources

Prognostic role of preoperative fluorine-18 fluorodeoxyglucose-positron emission tomography/computed tomography with an image-based harmonization technique: A multicenter retrospective studyCentral MessagePerspective

JTCVS Open, 2023
Objectives: Despite the prognostic impacts of preoperative fluorine-18 fluorodeoxyglucose-positron emission tomography/computed tomography examination, fluorine-18 fluorodeoxyglucose-positron emission tomography/computed tomography–based prognosis ...
Akira Hamada, MD, PhD, Kazuhiro Kitajima, MD, PhD, Kenichi Suda, MD, PhD, Takamasa Koga, MD, PhD, Junichi Soh, MD, PhD, Hayato Kaida, MD, PhD, Kimiteru Ito, MD, PhD, Tetsuro Sekine, MD, PhD, Kyoshiro Takegahara, MD, PhD, Hiromitsu Daisaki, PhD, Masaki Hashimoto, MD, PhD, Yukihiro Yoshida, MD, PhD, Takanobu Kabasawa, MD, PhD, Takashi Yamasaki, MD, Seiichi Hirota, MD, PhD, Jitsuo Usuda, MD, PhD, Kazunari Ishii, MD, PhD, Tetsuya Mitsudomi, MD, PhD   +17 more
doaj   +1 more source

Radiosynthesis of 5-[¹⁸F]Fluoro-1,2,3-triazoles through Aqueous Iodine–[¹⁸F]Fluorine Exchange Reaction

Molecules, 2021
In this report, a simple and efficient process to achieve fluorine-18-labeled 1,2,3-triazole is reported. The heteroaromatic radiofluorination was successfully achieved through an iodine–fluorine-18 exchange in an aqueous medium requiring only trace ...
Xiang Zhang, Falguni Basuli, Sameh Abdelwahed, Tadhg Begley, Rolf Swenson   +4 more
doaj   +1 more source

State of the art procedures towards reactive [18F]fluoride in PET tracer synthesis

EJNMMI Radiopharmacy and Chemistry, 2023
Background Positron emission tomography (PET) is a powerful, non-invasive preclinical and clinical nuclear imaging technique used in disease diagnosis and therapy assessment. Fluorine-18 is the predominant radionuclide used for PET tracer synthesis.
Lizeth Y. F. Haveman, Danielle J. Vugts, Albert D. Windhorst   +2 more
doaj   +1 more source