Results 1 to 10 of about 3,231,427 (376)
Fluorine-18: Radiochemistry and Target-Specific PET Molecular Probes Design [PDF]
Frontiers in Chemistry, 2022 The positron emission tomography (PET) molecular imaging technology has gained universal value as a critical tool for assessing biological and biochemical processes in living subjects.
Yunze Wang +11 more
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Preparation of Fluorine-18 [PDF]
Journal of Nuclear Science and Technology, 1964 Fluorine-18 was prepared by neutron irradiation of lithium carbonate in the reactor JRR-1. Five grams of lithium carbonate was irradiated for 2hr with a thermal neutron flux of 6×1011 n/cm2/sec. An alumina column was used to separate 18F from the irradiated material.
Eiji Shikata
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Isotopic Radiolabeling of Crizotinib with Fluorine-18 for In Vivo Pet Imaging [PDF]
Pharmaceuticals, 2022 Crizotinib is a tyrosine kinase inhibitor approved for the treatment of non-small-cell lung cancer, but it is inefficient on brain metastases. Crizotinib is a substrate of the P-glycoprotein, and non-invasive nuclear imaging can be used to assess the ...
Malvika Sardana +14 more
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Synthesis and Evaluation of Fluorine-18-Labeled L-Rhamnose Derivatives [PDF]
Molecules, 2023 The use of radiolabeled glucose for PET imaging resulted in the most commonly used tracer in the clinic, 2-deoxy-2-[18F]fluoroglucose (FDG). More recently, other radiolabeled sugars have been reported for various applications, including imaging tumors ...
Xiang Zhang +9 more
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Fluorine-18 Labelled Radioligands for PET Imaging of Cyclooxygenase-2 [PDF]
Molecules, 2022 Molecular imaging probes enable the early and accurate detection of disease-specific biomarkers and facilitate personalized treatment of many chronic diseases, including cancer.
Jatinder Kaur +2 more
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Fluorine-18 Radiochemistry, Labeling Strategies and Synthetic Routes [PDF]
Bioconjugate Chemistry, 2014 Fluorine-18 is the most frequently used radioisotope in positron emission tomography (PET) radiopharmaceuticals in both clinical and preclinical research.
Orit Jacobson +2 more
semanticscholar +4 more sources
Sulfonium Salts as Leaving Groups for Aromatic Labelling of Drug-like Small Molecules with Fluorine-18 [PDF]
Scientific Reports, 2015 Positron emission tomography (PET) is unique in that it allows quantification of biochemical processes in vivo, but difficulties with preparing suitably labelled radiotracers limit its scientific and diagnostic applications. Aromatic [18F]fluorination of
Kerstin Sander +6 more
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Recent Trends in Bioorthogonal Click-Radiolabeling Reactions Using Fluorine-18
Molecules, 2013 The increasing application of positron emission tomography (PET) in nuclear medicine has stimulated the extensive development of a multitude of novel and versatile bioorthogonal conjugation techniques especially for the radiolabeling of biologically ...
Doreen Pietzsch +2 more
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Medicine, 2015 To investigate the performance of fluorine-18-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET) and PET/computed tomography (CT) in the diagnosis, staging, restaging, and recurrence surveillance of bone sarcoma by systematically reviewing ...
Fanxiao Liu +8 more
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Fluorine-18 isotope scans of the sacroiliac joints. [PDF]
Annals of the Rheumatic Diseases, 1972 J. Webb +3 more
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