Results 181 to 190 of about 56,658 (237)
Some of the next articles are maybe not open access.
Infectious Disease Clinics of North America, 2009
Clinicians have enthusiastically used fluoroquinolones owing to their good safety profile and wide range of indications. This article reviews fluoroquinolone pharmacology, pharmacodynamic principles, and fluoroquinolone resistance mechanisms, highlighting recent trends in the epidemiology of fluoroquinolone resistance among gram-negative organisms and ...
exaly +4 more sources
Clinicians have enthusiastically used fluoroquinolones owing to their good safety profile and wide range of indications. This article reviews fluoroquinolone pharmacology, pharmacodynamic principles, and fluoroquinolone resistance mechanisms, highlighting recent trends in the epidemiology of fluoroquinolone resistance among gram-negative organisms and ...
exaly +4 more sources
Infectious Disease Clinics of North America, 2000
The fluoroquinolone class of antimicrobial agents has expanded dramatically in the last 5 years and will continue to grow over the next decade. This article discusses the newer fluoroquinolones in detail, including pharmacokinetics, pharmacodynamics, safety, and drug interactions, and the spectrum of in vitro activity.
J A, O'Donnell, S P, Gelone
+5 more sources
The fluoroquinolone class of antimicrobial agents has expanded dramatically in the last 5 years and will continue to grow over the next decade. This article discusses the newer fluoroquinolones in detail, including pharmacokinetics, pharmacodynamics, safety, and drug interactions, and the spectrum of in vitro activity.
J A, O'Donnell, S P, Gelone
+5 more sources
Mayo Clinic Proceedings, 1991
The fluoroquinolone class of antibiotics promises to become as diverse and as important as beta-lactam agents. The fluoroquinolones inhibit bacterial DNA gyrase and are bactericidal. All fluoroquinolones have potent activity against most gram-negative bacteria; ciprofloxacin is the most active against Pseudomonas aeruginosa.
R C, Walker, A J, Wright
openaire +2 more sources
The fluoroquinolone class of antibiotics promises to become as diverse and as important as beta-lactam agents. The fluoroquinolones inhibit bacterial DNA gyrase and are bactericidal. All fluoroquinolones have potent activity against most gram-negative bacteria; ciprofloxacin is the most active against Pseudomonas aeruginosa.
R C, Walker, A J, Wright
openaire +2 more sources
Fluoroquinolone Use and Fluoroquinolone Resistance: Is There an Association?
Clinical Infectious Diseases, 1994In an assessment of potential risk factors for nosocomial infections caused by fluoroquinolone-resistant gram-negative organisms, 68 patients who developed a nosocomial infection caused by a fluoroquinolone-resistant gram-negative bacillus were compared with 191 patients who developed a nosocomial infection caused by a fluoroquinolone-susceptible gram ...
P, Richard +6 more
openaire +2 more sources
Fluoroquinolones and tuberculosis
Expert Opinion on Investigational Drugs, 2002Tuberculosis (TB) remains one of the main causes of morbidity worldwide, and the emergence of multi-drug resistant (MDR) Mycobacterium tuberculosis strains in some parts of the world has become a major concern. The decrease in activity of the major anti-TB drugs, such as isoniazid and rifampicin, is an important threat and alternative therapies are ...
André, Bryskier, John, Lowther
openaire +2 more sources
Fluoroquinolones in Paediatrics
Drugs, 1999Fluoroquinolones have a broad spectrum of activity against gram-positive, gram-negative, and mycobacterial organisms as well as anaerobes, Mycoplasma, Chlamydia, Ureaplasma, and Legionella spp. They have excellent oral bioavailability, with good tissue penetration, and long elimination half-lives. The experience with fluoroquinolones in paediatrics has
H S, Jafri, G H, McCracken
openaire +2 more sources
Ophthalmology, 2009
To report a possible association between fluoroquinolones and diplopia.Database study.A total of 171 subjects were studied.Spontaneous reports from the National Registry of Drug-Induced Ocular Side Effects, World Health Organization, and Food and Drug Administration were collected on fluoroquinolones and diplopia.Data garnered from the spontaneous ...
Frederick W, Fraunfelder +1 more
openaire +2 more sources
To report a possible association between fluoroquinolones and diplopia.Database study.A total of 171 subjects were studied.Spontaneous reports from the National Registry of Drug-Induced Ocular Side Effects, World Health Organization, and Food and Drug Administration were collected on fluoroquinolones and diplopia.Data garnered from the spontaneous ...
Frederick W, Fraunfelder +1 more
openaire +2 more sources
Dysglycaemias and Fluoroquinolones
Drug Safety, 2008The fluoroquinolones are an extremely popular class of antibacterials, owing to their broad spectrum of activity and the convenience of their intravenous and oral dosage formulations. Overall, the currently available fluoroquinolones have a good safety profile; however, certain fluoroquinolones within the class have been associated with severe and life-
Roshan J, Lewis, John F, Mohr
openaire +2 more sources
The fluoroquinolones - reappraisal
International Journal of Antimicrobial Agents, 1992The fluoroquinolones (FQ) still appear to draw major interest despite the fact that they have already been used for about a decade. The International Journal of Antimicrobial Agents has published four extensive reviews on norfloxacin, pefloxacin, ciprofloxacin, ofloxacin in its recent issues; two thirds of the pages of the first issue of the journal ...
E, Rubinstein, C, Carbon
openaire +2 more sources