Results 1 to 10 of about 16,766 (241)

Effective inhibition of foot-and-mouth disease virus (FMDV) replication in vitro by vector-delivered microRNAs targeting the 3D gene [PDF]

Virology Journal, 2011
Background Foot-and-mouth disease virus (FMDV) causes an economically important and highly contagious disease of cloven-hoofed animals. RNAi triggered by small RNA molecules, including siRNAs and miRNAs, offers a new approach for controlling viral ...
Cai Xuepeng, Lin Tong, Shao Junjun, Cong Guozheng, Zhang Guofeng, Luo Jihuai, Gao Shandian, Du Junzheng, Chang Huiyun   +8 more
doaj   +7 more sources

RNA‐Seq analysis reveals the different mechanisms triggered by bovine and equine after infection with FMDV [PDF]

Veterinary Medicine and Science
Background Foot‐and‐mouth disease virus (FMDV) is an important pathogen of the MicroRNA virus family. Infection of livestock can cause physical weakness, weight loss, reduced milk production, and a significant reduction in productivity for an extended ...
Yi Wu, Lu Li, Wanfu Bai, Tao Li, Xiaoying Qian, Yiyi Liu, Shenyuan Wang, Chunxia Liu, Fang Wan, Dong Zhang, Yingchun Liu, Kaifeng Wu, Yu Ling, Huanmin Zhou, Fanhua Meng, Yanru Zhang, Junwei Cao   +16 more
doaj   +3 more sources

FMDV 3A Antagonizes the Effect of ANXA1 to Positively Modulate Viral Replication

Journal of Virology, 2022
FMDV is a pathogen that causes one of the world’s most destructive and highly contagious animal diseases. The FMDV 3A protein plays a critical role in viral replication and host range.
Xusheng Ma, Keshan Zhang, Zhikuan Luo, Xiaofeng Nian, Sk Mohiuddin Choudhury, Zixiang Zhu, Rui Song, Jingjing Pei, Yanli Huo, Yuanyuan Li, Fan Yang, Weijun Cao, Huisheng Liu, Xiangtao Liu, Haixue Zheng   +14 more
openalex   +2 more sources

Transcript Profiling Identifies Early Response Genes against FMDV Infection in PK-15 Cells [PDF]

Viruses, 2018
Foot-and-mouth disease (FMD) is a highly contagious disease that results in enormous economic loses worldwide. Although the protection provided by vaccination is limited during early infection, it is recognized as the best method to prevent FMD outbreaks.
Tianliang Zhang, Hao-tai Chen, Linlin Qi, Jie Zhang, Run Wu, Yongguang Zhang, Yuefeng Sun   +6 more
openalex   +2 more sources

FMDV replicons encoding green fluorescent protein are replication competent [PDF]

Journal of Virological Methods, 2014
The study of replication of viruses that require high bio-secure facilities can be accomplished with less stringent containment using non-infectious 'replicon' systems. The FMDV replicon system (pT7rep) reported by Mclnerney et al. (2000) was modified by
Angus I. Lamond, Belsham, Belsham, Chang, Chinsangaram, David J. Rowlands, Devaney, Donnelly, Ellard, Fiona Tulloch, Forss, Garry A. Luke, Gu, John Nicholson, Juergen Haas, Kirchweger, Martin D. Ryan, Mason, McKnight, Mclnerney, Nicola J. Stonehouse, Ormö, Piccone, Ryan, Ryan, Strebel, Terry Jackson, Toby Tuthill, Uday Pathania   +28 more
core   +5 more sources

Foot-and-mouth disease virus localisation on follicular dendritic cells and sustained induction of neutralising antibodies is dependent on binding to complement receptors (CR2/CR1). [PDF]

PLoS Pathogens, 2022
Previous studies have shown after the resolution of acute infection and viraemia, foot-and-mouth disease virus (FMDV) capsid proteins and/or genome are localised in the light zone of germinal centres of lymphoid tissue in cattle and African buffalo.
Lucy Gordon, Neil Mabbott, Joanna Wells, Liudmila Kulik, Nick Juleff, Bryan Charleston, Eva Perez-Martin   +6 more
doaj   +3 more sources

A Prime-Boost Vaccination Strategy in Cattle to Prevent Foot-and-Mouth Disease Using a "Single-Cycle" Alphavirus Vector and Empty Capsid Particles. [PDF]

PLoS ONE, 2016
Foot-and-mouth disease (FMD) remains one of the most economically important infectious diseases of production animals globally. Vaccination can successfully control this disease, however, current vaccines are imperfect.
Maria Gullberg, Louise Lohse, Anette Bøtner, Gerald M McInerney, Alison Burman, Terry Jackson, Charlotta Polacek, Graham J Belsham   +7 more
doaj   +6 more sources

Characterization of Asia 1 sdAb from Camels Bactrianus (C. bactrianus) and Conjugation with Quantum Dots for Imaging FMDV in BHK-21 Cells

PLoS ONE, 2013
Foot-and-mouth disease (FMD), caused by FMD virus (FMDV), is a highly contagious viral disease affecting cloven-hoofed animals. Camelids have a unique immunoglobulin profile, with the smallest functional heavy-chain antibodies (sdAb or VHH) naturally ...
Shuanghui Yin, Shunli Yang, Shang YouJun, Shiqi Sun, Guangqing Zhou, Jin Ye, Hong Tian, Jinyan Wu, Xiangtao Liu   +8 more
openalex   +3 more sources

Protein coexpression using FMDV 2A : effect of “linker” residues [PDF]

BioMed Research International, 2013
This article was made open access through BIS OA funding. The research was supported by the MRC.Many biomedical applications absolutely require, or are substantially enhanced by, coexpression of multiple proteins from a single vector.
Minskaia, Ekaterina, Ryan, Martin D.
core   +3 more sources

An evaluation of the efficiency and effectiveness of diagnostic tests for foot and mouth disease: are novel diagnostic tests for FMD more feasible than conventional tests in Southeast Asia? [PDF]

Aust Vet J
Foot and mouth disease (FMD) remains endemic in many areas of continental Southeast Asia (SEA). It is responsible for substantial economic losses in the smallholder sector and threatens livelihoods. In recent years, novel diagnostic tests have been developed which reportedly detect FMD virus more effectively and efficiently.
Tan WY, Ward MP.
europepmc   +2 more sources