BackgroundshRNA targeting the integrin αv subunit, which is the foot-and-mouth disease virus (FMDV) receptor, plays a key role in virus attachment to susceptible cells.
Jihuai Luo+8 more
semanticscholar +1 more source
Virulence beneath the fleece; a tale of foot-and-mouth disease virus pathogenesis in sheep.
Foot-and-mouth disease virus (FMDV) is capable of infecting all cloven-hoofed domestic livestock species, including cattle, pigs, goats, and sheep. However, in contrast to cattle and pigs, the pathogenesis of FMDV in small ruminants has been incompletely
Carolina Stenfeldt+5 more
doaj +1 more source
Development and evaluation of tailored specific real-time RT-PCR assays for detection of foot-and-mouth disease virus serotypes circulating in East Africa [PDF]
Rapid, reliable and accurate diagnostic methods provide essential support to programmes that monitor and control foot-and-mouth disease (FMD). While pan-specific molecular tests for FMD virus (FMDV) detection are well established and widely used in ...
Bachanek-Bankowska, Katarzyna+8 more
core +1 more source
A single amino acid substitution in the capsid of foot-and-mouth disease virus can increase acid resistance [PDF]
Foot-and-mouth disease virus (FMDV) particles lose infectivity due to their disassembly at pH values slightly below neutrality. This acid-dependent disassembly process is required for viral RNA release inside endosomes.
Martín-Acebes, Miguel Ángel+4 more
core +1 more source
Plant virus-based expression systems provide attractive alternatives for production of animal virus-originated antigenic peptides. In the present study, an infectious cDNA clone of Tobacco necrosis virus A Chinese isolate (TNV-A(C)) was used for ...
Yongliang Zhang+9 more
semanticscholar +1 more source
RNAiFold2T: Constraint Programming design of thermo-IRES switches
Motivation: RNA thermometers (RNATs) are cis-regulatory ele- ments that change secondary structure upon temperature shift. Often involved in the regulation of heat shock, cold shock and virulence genes, RNATs constitute an interesting potential resource ...
Clote, Peter+6 more
core +2 more sources
Development of a competitive chemiluminescence immunoassay using a monoclonal antibody recognizing 3B of foot-and-mouth disease virus for the rapid detection of antibodies induced by FMDV infection [PDF]
Wei Liu+8 more
openalex +1 more source
Production of FMDV virus-like particles by a SUMO fusion protein approach in Escherichia coli
Virus-like particles (VLPs) are formed by the self-assembly of envelope and/or capsid proteins from many viruses. Some VLPs have been proven successful as vaccines, and others have recently found applications as carriers for foreign antigens or as ...
Chien-Der Lee+3 more
semanticscholar +1 more source
Use of Protein Pegylation to Prolong the Antiviral Effect of IFN Against FMDV [PDF]
Fayna Díaz-San Segundo+9 more
openalex +1 more source
The interaction between foot-and-mouth disease virus (FMDV) and the host is extremely important for virus infection, but there are few researches on it, which is not conducive to vaccine development and FMD control.
Gaochuang Peng+11 more
doaj +1 more source