Results 121 to 130 of about 18,513 (243)

Lentviral-mediated RNAi to inhibit target gene expression of the porcine integrin αv subunit, the FMDV receptor, and against FMDV infection in PK-15 cells

open access: yesVirology Journal, 2011
BackgroundshRNA targeting the integrin αv subunit, which is the foot-and-mouth disease virus (FMDV) receptor, plays a key role in virus attachment to susceptible cells.
Jihuai Luo   +8 more
semanticscholar   +1 more source

Virulence beneath the fleece; a tale of foot-and-mouth disease virus pathogenesis in sheep.

open access: yesPLoS ONE, 2019
Foot-and-mouth disease virus (FMDV) is capable of infecting all cloven-hoofed domestic livestock species, including cattle, pigs, goats, and sheep. However, in contrast to cattle and pigs, the pathogenesis of FMDV in small ruminants has been incompletely
Carolina Stenfeldt   +5 more
doaj   +1 more source

Development and evaluation of tailored specific real-time RT-PCR assays for detection of foot-and-mouth disease virus serotypes circulating in East Africa [PDF]

open access: yes, 2016
Rapid, reliable and accurate diagnostic methods provide essential support to programmes that monitor and control foot-and-mouth disease (FMD). While pan-specific molecular tests for FMD virus (FMDV) detection are well established and widely used in ...
Bachanek-Bankowska, Katarzyna   +8 more
core   +1 more source

A single amino acid substitution in the capsid of foot-and-mouth disease virus can increase acid resistance [PDF]

open access: yes, 2015
Foot-and-mouth disease virus (FMDV) particles lose infectivity due to their disassembly at pH values slightly below neutrality. This acid-dependent disassembly process is required for viral RNA release inside endosomes.
Martín-Acebes, Miguel Ángel   +4 more
core   +1 more source

Development of Tobacco necrosis virus A as a vector for efficient and stable expression of FMDV VP1 peptides.

open access: yesPlant Biotechnology Journal, 2010
Plant virus-based expression systems provide attractive alternatives for production of animal virus-originated antigenic peptides. In the present study, an infectious cDNA clone of Tobacco necrosis virus A Chinese isolate (TNV-A(C)) was used for ...
Yongliang Zhang   +9 more
semanticscholar   +1 more source

RNAiFold2T: Constraint Programming design of thermo-IRES switches

open access: yes, 2016
Motivation: RNA thermometers (RNATs) are cis-regulatory ele- ments that change secondary structure upon temperature shift. Often involved in the regulation of heat shock, cold shock and virulence genes, RNATs constitute an interesting potential resource ...
Clote, Peter   +6 more
core   +2 more sources

Production of FMDV virus-like particles by a SUMO fusion protein approach in Escherichia coli

open access: yesJournal of Biomedical Sciences, 2009
Virus-like particles (VLPs) are formed by the self-assembly of envelope and/or capsid proteins from many viruses. Some VLPs have been proven successful as vaccines, and others have recently found applications as carriers for foreign antigens or as ...
Chien-Der Lee   +3 more
semanticscholar   +1 more source

Use of Protein Pegylation to Prolong the Antiviral Effect of IFN Against FMDV [PDF]

open access: gold, 2021
Fayna Díaz-San Segundo   +9 more
openalex   +1 more source

A genome-wide CRISPR screening uncovers that TOB1 acts as a key host factor for FMDV infection via both IFN and EGFR mediated pathways.

open access: yesPLoS Pathogens
The interaction between foot-and-mouth disease virus (FMDV) and the host is extremely important for virus infection, but there are few researches on it, which is not conducive to vaccine development and FMD control.
Gaochuang Peng   +11 more
doaj   +1 more source

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