Results 11 to 20 of about 13,911 (208)

FMDV 3A cooperates with PDCD10 to promote FMDV replication by inhibiting VISA-mediated innate immunity. [PDF]

J Virol
ABSTRACT RIG-I like receptors (RLRs) recognize RNA viruses and induce an innate immune response. Although many host factors strictly regulate the signal transduction of the RLR pathway, the mechanisms remain unclear. In the present study, we demonstrated that virus infection slightly increased
Li Q, Nian X, Shang X, Zeng Z, Luo Z, Du B, Ma M, Zhu Z, Yang F, Pei J, Cao W, Yan H, Li L, Xu Y, Ma X, Zheng H.   +15 more
europepmc   +2 more sources

Cloning and expression of non-structural 3ABC gene from FMD virus serotype O in Escherichia coli [PDF]

مجله بیوتکنولوژی کشاورزی, 2015
After about one hundred year after its identification, Foot and Mouth Disease (FMD) is the first viral disease in animals that impose a major risk to  the world's livestock industry.
Seyyed Amir Reza Parizadeh, Mohmmad Reza Nasiri, Saeid Zibaei, Mojtaba Tahmoures Pour, Mohmmad Reza Basami   +4 more
doaj   +1 more source

Comparative expression analysis of inflammatory and immune-related genes in cattle during acute infection with foot-and-mouth disease virus in Egypt

Journal of Veterinary Research, 2021
Foot-and-mouth disease is a highly infectious viral disease affecting all cloven-footed domestic animals. The three foot-and-mouth disease virus (FMDV) serotypes A, O and SAT2 are at present the greatest threat to susceptible animals in Egypt. The aim of
El Nahas Abeer F., Abd El Naby Walaa S.H., Khatab Shymaa A., Fergany Al-Zahraa A., Rashed Rashed R.   +4 more
doaj   +1 more source

The Carrier Conundrum; A Review of Recent Advances and Persistent Gaps Regarding the Carrier State of Foot-and-Mouth Disease Virus

Pathogens, 2020
The existence of a prolonged, subclinical phase of foot-and-mouth disease virus (FMDV) infection in cattle was first recognized in the 1950s. Since then, the FMDV carrier state has been a subject of controversy amongst scientists and policymakers.
Carolina Stenfeldt, Jonathan Arzt
doaj   +1 more source

Protein Coexpression Using FMDV 2A: Effect of “Linker” Residues [PDF]

BioMed Research International, 2013
Many biomedical applications absolutely require, or are substantially enhanced by, coexpression of multiple proteins from a single vector. Foot-and-mouth disease virus 2A (F2A) and “2A-like” sequences (e.g.,Thosea asignavirus 2A; T2A) are used widely for this purpose since multiple proteins can be coexpressed by linking open reading frames (ORFs) to ...
Minskaia, Ekaterina, Ryan, Martin D.
openaire   +4 more sources

Transient Expression of Coat Protein of Foot and Mouth Disease Virus (FMDV) in Alfalfa (Medicago sativa) by Agroinfiltration [PDF]

Journal of Cell and Molecular Research, 2016
An Agrobacterium-mediated transient gene expression assay was carried out in alfalfa (Medicago sativa) leaves for expression of a chimeric gene encoding a part of capsid protein of Foot and Mouth Disease virus called VP1.
Maziar Habibi-Pirkoohi, Saeid Malekzadeh-Shafaroudi, Hasan Marashi, Saeid Zibaee, Afsaneh Mohkami, Saba NejatizaXeh   +5 more
doaj   +1 more source

Heterogeneity and Recombination of Foot-and-Mouth Disease Virus during Multi-Strain Coinfection of Cattle

mSphere, 2023
Superinfection of cattle persistently infected with foot-and-mouth disease virus (FMDV), with a heterologous FMDV strain has been shown to generate novel recombinant viruses.
Carolina Stenfeldt, Ian Fish, Haillie C. Meek, Jonathan Arzt   +3 more
doaj   +1 more source

Recovery of viral RNA and infectious foot-and-mouth disease virus from positive lateral-flow devices [PDF]

, 2014
Foot-and-mouth disease Virus (FMDV) is an economically important, highly contagious picornavirus that affects both wild and domesticated cloven hooved animals. In developing countries, the effective laboratory diagnosis of foot-and-mouth disease (FMD) is
Armson, Bryony, Bankowski, Bartlomiej M., Barnett, Paul V., Di Nardo, Antonello, Ferris, Nigel P., Fowler, Veronica L., King, Donald P., Mioulet, Valerie, Reid, Scott M., Valdazo-Gonzalez, Begoña, Wadsworth, Jemma   +10 more
core   +2 more sources

Antiviral Activity Of Adamantane-Pyrazole Derivatives Against Foot And Mouth Disease Virus Infection In Vivo And In Vitro With Molecular Docking Study

Journal of Applied Veterinary Sciences, 2020
Foot-and-mouth disease (FMD) vaccine does not afford early effective protection until adaptive immune protection caused by the vaccination occurs. Therefore, an alternative prophylactic application of antiviral agents for inhibition of the FMD virus is ...
Mohammed M. S. Wassel, Wael M. Gamal El-Din , Ahmed Ragab, Gameel A. M. Elhag Ali, Yousry A. Ammar   +4 more
doaj   +1 more source

Picornavirus infection enhances aspartate by the SLC38A8 transporter to promote viral replication.

PLoS Pathogens, 2023
Foot-and-mouth disease, a class of animal diseases, is caused by foot-and-mouth disease virus (FMDV). The metabolic changes during FMDV infection remain unclear. Here, PK-15 cells, serum, and tonsils infected with FMDV were analyzed by metabolomics.
Huisheng Liu, Zixiang Zhu, Qiao Xue, Fan Yang, Weijun Cao, Zhaoning Xue, Xiangtao Liu, Haixue Zheng   +7 more
doaj   +1 more source