Results 11 to 20 of about 1,380 (137)

Osteogenic differentiation of mesenchymal stem cells in cell-laden culture of self-assembling peptide hydrogels [PDF]

OpenNano
Mesenchymal stem cell (MSC) osteogenic differentiation requires scaffolds to support multiple stages of growth and differentiation signals. Fluorenyl-9-methoxycarbonyl diphenylalanine (Fmoc-FF) peptides self-assemble to create 3D nanofibers.
Faye Fouladgar, Robert Powell, Vishalakshi Irukuvarjula, Akhila Joy, Xiao Li, Neda Habibi   +5 more
doaj   +2 more sources

Biomechanical Stimulation of Mesenchymal Stem Cells in 3D Peptide Nanofibers for Bone Differentiation [PDF]

Journal of Functional Biomaterials
Mechanical stimulation critically regulates mesenchymal stem cell (MSC) differentiation, yet its effects in three-dimensional (3D) environments remain poorly defined. Here, we developed a custom dynamic stretcher integrating poly(dimethylsiloxane) (PDMS)
Faye Fouladgar, Robert Powell, Emily Carney, Andrea Escobar Martinez, Amir Jafari, Neda Habibi   +5 more
doaj   +2 more sources

Peptide-Based Hydrogels and Nanogels for Delivery of Doxorubicin [PDF]

International Journal of Nanomedicine, 2021
Enrico Gallo,1 Carlo Diaferia,2 Elisabetta Rosa,2 Giovanni Smaldone,1 Giancarlo Morelli,2 Antonella Accardo2 1IRCCS SDN, Naples, 80143, Italy; 2Department of Pharmacy and Research Centre on Bioactive Peptides (CIRPeB), University of Naples &ldquo ...
Gallo E, Diaferia C, Rosa E, Smaldone G, Morelli G, Accardo A   +5 more
doaj   +3 more sources

Hydrogel as a Platform for Point-of-Care Calcium Determination in Blood [PDF]

Gels
Calcium is a key macroelement involved in a range of physiological processes in the body, and its concentration in blood is an important diagnostic indicator in various diseases. This work presents a novel rapid method for the point-of-care determination
Tatiana N. Tikhonova, Anastasia V. Barkovaya, Yuri M. Efremov, Vladimir I. Panov, Peter S. Timashev, Victor V. Fadeev   +5 more
doaj   +2 more sources

FmocFF Peptide Hydrogel Is a Promising Matrix for Encapsulation and Controlled Release of the Anticancer Peptide Drug Bortezomib [PDF]

Biomolecules
One major public health issue is cancer chemotherapy; despite constant progress in the area, administration of anticancer drugs to patients is often associated with serious side effects.
Peter Divanach, Antzela Noti, Panagiotis Vouvopoulos, Thanasis Athanasiou, Nikos Kountourakis, Vagelis Harmandaris, Anastassia N. Rissanou, Anna Mitraki   +7 more
doaj   +2 more sources

Gaseous Synergistic Self‐Assembly and Arraying to Develop Bio‐Organic Photocapacitors for Neural Photostimulation [PDF]

Advanced Science
Bioinspired supramolecular architectonics is attracting increasing interest due to their flexible organization and multifunctionality. However, state‐of‐the‐art bioinspired architectonics generally take place in solvent‐based circumstance, thus leading ...
Xinyuan Fan, Yiming Tang, Jiahao Zhang, Kang Ma, Zhengyu Xu, Yuying Liu, Bin Xue, Yi Cao, Deqing Mei, Wei Wang, Guanghong Wei, Kai Tao   +11 more
doaj   +2 more sources

Mesenchymal stem cells aligned and stretched in self-assembling peptide hydrogels [PDF]

Heliyon
The presented research highlights a novel approach using fmoc-protected peptide hydrogels for the encapsulation and stretching of mesenchymal stem cells (MSCs).
Farzaneh Fouladgar, Forough Ghasem Zadeh Moslabeh, Yashesh Varun Kasani, Nick Rogozinski, Marc Torres, Melanie Ecker, Huaxiao Yang, Yong Yang, Neda Habibi   +8 more
doaj   +2 more sources

Experimental and Computational Study of Injectable Iron(III)/Ultrashort Peptide Hydrogels: A Candidate for Ferroptosis‐Induced Treatment of Bacterial Infections [PDF]

Small Science
Injectable hydrogels are promising candidates as local drug delivery platforms for the treatment of infected wounds. Self‐assembled small peptide hydrogels are of interest due to their high biocompatibility, degradability, and ease of synthesis.
Capucine Loth, Florent Barbault, Cécile Guégan, Flora Lemaire, Christophe Contal, Alain Carvalho, Sophie Hellé, Marie Champion, Halima Kerdjoudj, Delphine Chan‐Seng, Lydie Ploux, Fouzia Boulmedais   +11 more
doaj   +2 more sources

Xeno-Free Biocompatible Peptide-Based Bioinks Reinforced with Cellulose Nanofibers for 3D Printing. [PDF]

Adv Healthc Mater
A xeno‐free bioink combining self‐assembled peptides and cellulose nanofibers is developed for 3D printing. The bioink forms a non‐cross‐linked 3D scaffold, mimicking the extracellular matrix and supporting over 95% cell viability. This approach offers enhanced biocompatibility and mechanical stability, advancing 3D printing for personalized medicine ...
Netti F, Tsuriano M, Rattner N, Altobelli V, Dan Y, Adler-Abramovich L.   +5 more
europepmc   +2 more sources

Differently N‐Capped Analogues of Fmoc‐FF

Chemistry – A European Journal, 2023
AbstractShort and ultra‐short peptides have been recently envisioned as excellent building blocks for the formulation of hydrogels with appealing properties. Due to its simplicity and capability to gel under physiological conditions, Fmoc‐FF (Nα‐fluorenylmethoxycarbonyl‐diphenylalanine), remains one of the most studied low molecular‐weight ...
Diaferia, Carlo, Rosa, Elisabetta, Gallo, Enrico, Morelli, Giancarlo, Accardo, Antonella   +4 more
openaire   +3 more sources