Results 171 to 180 of about 1,278,750 (244)

Estrogen Receptor Beta Isoforms Interplay Integrates Nuclear and Extra‐Nuclear Signaling to Modulate Human Granulosa Cell Growth

The FASEB Journal, Volume 40, Issue 19, 15 October 2026.
Working model of ERβ isoform signaling in human granulosa cells. Upon E2 binding, ERβ1 activates ERE‐dependent transcription and represses AP‐1 activity through Jun/Fos interactions. In contrast, ERβ2, ERβ4, and ERβ5 lack E2 binding and ERE activity but promote AP‐1‐dependent transcription and counteract ERβ1 repression, including after phosphorylation
Clémentine Marie, Inza‐Noor Baskaran, Raphaël Corre, Anne Mayeur, Michaël Grynberg, Guillaume Chevreux, David L'Hôte, Joëlle Cohen‐Tannoudji, Stéphanie Chauvin   +8 more
wiley   +1 more source

Protective influence of hyaluronic acid on focal adhesion kinase activity in human skin fibroblasts exposed to ethanol

, 2017
Magdalena Donejko,1 Edyta Rysiak,2 Elżbieta Galicka,1 Robert Terlikowski,3 Edyta Katarzyna Głażewska,1 Andrzej Przylipiak1 1Department of Esthetic Medicine, 2Department of Medicinal Chemistry, Faculty of Pharmacy, 3Department of Health Restoration ...
Głażewska EK, Przylipiak A, Donejko M, Galicka E, Rysiak E, Terlikowski R   +5 more
core  

Focal adhesion kinase FAK interplays with ROR1 in the aggressiveness of chronic lymphocytic leukemia. [PDF]

BMC Med
Castronuovo M, Capasso G, Beltrame A, Mouawad N, Gramegna V, Fantato P, Pagnin E, Angotzi F, Cellini A, Serafin A, Facco M, Visentin A, Trentin L, Frezzato F.   +13 more
europepmc   +1 more source

Phagocyte Transcriptomic Analysis Reveals Focal Adhesion Kinase (FAK) and Heparan Sulfate Proteoglycans (HSPGs) as Major Regulators in Anti-bacterial Defense of Crassostrea hongkongensis. [PDF]

Front Immunol, 2020
Lin Y, Mao F, Wong NK, Zhang X, Liu K, Huang M, Ma H, Xiang Z, Li J, Xiao S, Zhang Y, Yu Z.   +11 more
europepmc   +1 more source

Inactivation of Focal Adhesion Kinase FAK Rapidly Abrogates Keratinocyte Entry in Mitosis via Rho-Associated Kinase, Resulting in Squamous Differentiation. [PDF]

FASEB J
Contreras L, García-Gaipo L, García-Reija F, Castro A, García-Pedrero JM, Lorca T, Gandarillas A.   +6 more
europepmc   +1 more source

Focal adhesion kinase (FAK): emerging target for drug-resistant malignant tumors. [PDF]

Mol Biol Rep
Aakriti J, Vithalkar MP, Maity S, Baby K, Nagareddy PR, Nayak Y.   +5 more
europepmc   +1 more source

Fascin Activates β-Catenin Signaling and Promotes Breast Cancer Stem Cell Function Mainly Through Focal Adhesion Kinase (FAK): Relation With Disease Progression. [PDF]

Front Oncol, 2020
Barnawi R, Al-Khaldi S, Bakheet T, Fallatah M, Alaiya A, Ghebeh H, Al-Alwan M.   +6 more
europepmc   +1 more source

Clinical Importance of Focal Adhesion Kinase (FAK)-Src and Paxillin Expression in Renal Cell Carcinoma. [PDF]

Cureus
Mitsos P, Anastasiou I, Constantinides C, Deligiannis D, Katafigiotis I, Papakonstantinou A, Tzotzola V, Mitropoulos D, Theocharis S.   +8 more
europepmc   +1 more source

Focal adhesion kinase inhibition induces membrane accumulation of aquaporin-2 in renal epithelial cells by actin depolymerization and endocytosis inhibition. [PDF]

Am J Physiol Renal Physiol
Tchakal-Mesbahi A, He J, Zhu S, Huang M, Fukushima K, Bouley R, Brown D, Lu HAJ.   +7 more
europepmc   +1 more source

Potential Role of Integrin α₅β₁/Focal Adhesion Kinase (FAK) and Actin Cytoskeleton in the Mechanotransduction and Response of Human Gingival Fibroblasts Cultured on a 3-Dimension Lactide-Co-Glycolide (3D PLGA) Scaffold. [PDF]

Med Sci Monit, 2020
Wei L, Chen Q, Zheng Y, Nan L, Liao N, Mo S.   +5 more
europepmc   +1 more source