Results 171 to 180 of about 14,832,680 (288)

Follicular helper T cells: potential therapeutic targets in rheumatoid arthritis. [PDF]

Cell Mol Life Sci, 2021
Lu J, Wu J, Xia X, Peng H, Wang S.
europepmc   +1 more source

Treatment‐Driven Peripheral Blood Transcriptomic Remodeling and Baseline Predictors of ESSDAI and STAR Response to B Cell Therapy in Sjögren's Disease

Arthritis &Rheumatology, EarlyView.
Graphical Abstract Objective This study aimed to characterize whole blood transcriptomic profiles in adults with active Sjögren's disease (SjD) treated with anti‐CD20 or B lymphocyte stimulator/BAFF inhibition, identify markers of clinical response, and define inflammatory pathways linked to nonresponse. Methods Whole blood RNA sequencing was performed
Aimen Ibrahim, Junjie Peng, Eileen Tian, Lucia Martin‐Gutierrez, John Casement, Kyle Thompson, Wan‐Fai Ng, André van Maurik, Elizabeth C. Jury, Coziana Ciurtin   +9 more
wiley   +1 more source

Bcl6-Mediated Transcriptional Regulation of Follicular Helper T cells (T_FH). [PDF]

Trends Immunol, 2021
Choi J, Crotty S.
europepmc   +1 more source

Differentiation and Pathological Significance of Tissue‐Resident Memory‐Like CD8+ T Cells in Systemic Lupus Erythematosus

Arthritis &Rheumatology, Accepted Article.
Objective Tissue‐resident memory T (TRM) cells have been implicated in organ‐specific immune pathology; however, the pathological relevance of TRM‐like CD8+ T cells in systemic lupus erythematosus (SLE) remains unclear. We investigated their differentiation mechanisms and pathological significance in SLE, including associations with disease activity ...
Yuya Fujita, Kaoru Yamagata, Satoshi Kubo, Ippei Miyagawa, Koshiro Sonomoto, Yurie Satoh‐Kanda, Masanobu Ueno, Shumpei Kosaka, Aya Nawata, Yoshiya Tanaka, Shingo Nakayamada   +10 more
wiley   +1 more source

Editorial: Follicular helper T cells in immunity and autoimmunity, volume II. [PDF]

Front Immunol
Salek-Ardakani S, Fousteri G, Cicalese MP.   +2 more
europepmc   +1 more source

Status of oncology drugs with a conditional approval: A cross‐sectional comparison of the Food and Drug Administration and Health Canada

British Journal of Clinical Pharmacology, EarlyView.
Aims This study looks at the status of the same drugs conditionally approved by the Food and Drug Administration and Health Canada for the same oncology indication. Methods Lists of oncology drugs with a conditional approval from the Food and Drug Administration and Health Canada were generated and drug pairs with the same indication were matched ...
Joel Lexchin
wiley   +1 more source

Not Only Follicular Helper T-Cells but Also Peripheral Helper T-Cells Expanded Correlate With Disease Severity and B-Cell Differentiation in Graves' Disease. [PDF]

Int J Endocrinol
Huang Z, Jiang Y, Zhang X, Yang X, Song R, Zhang JA.   +5 more
europepmc   +1 more source

Lactobacillus improves the effects of prednisone on autoimmune hepatitis via gut microbiota-mediated follicular helper T cells. [PDF]

Cell Commun Signal, 2022
Ma L, Zhang L, Zhuang Y, Ding Y, Chen J.
europepmc   +1 more source

Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics

British Journal of Clinical Pharmacology, EarlyView.
Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay, Amandine Manon, Hunter Stephens, S. Y. Amy Cheung, Bart de Keizer, Erik T. te Beek   +5 more
wiley   +1 more source

Follicular Helper T Cells: Potential Interventional Targets in Atherosclerosis. [PDF]

J Immunol Res
Chen Y, Wang W, Xia X, Xu X, Wang S, Gurumallesh P.   +5 more
europepmc   +1 more source